T-Box 5 Produits
(T-Box 5 (TBX5))
Catégories
This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene is closely linked to related family member T-box 3 (ulnar mammary syndrome) on human chromosome 12. The encoded protein may play a role in heart development and specification of limb identity. Mutations in this gene have been associated with Holt-Oram syndrome, a developmental disorder affecting the heart and upper limbs. Several transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008].
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Catégories T-Box 5 en vedette
T-Box 5 Anticorps
High quality antibodies with extensive validation data.
T-Box 5 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
T-Box 5 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, ELISA, RNAi
Validations
- (3)
- (3)
N° du produit
ABIN563098
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC
Validations
- (3)
N° du produit
ABIN7239203
Quantité
200 μL
Fiche technique
Fiche technique
Reactivity
Bat, Chicken, Cow, Dog, Goat, Guinea Pig, Hamster, Horse, Human, Monkey, Mouse, Pig, Rabbit, Rat, Sheep, Xenopus laevis, Zebrafish (Danio rerio)
Application
WB, IHC, IHC (p)
Validations
- (3)
N° du produit
ABIN6741551
Quantité
100 μL
Fiche technique
Fiche technique
T-Box 5 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN6221767
Quantité
96 tests
Fiche technique
Fiche technique
T-Box 5 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1322304
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1322302
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7423756
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits T-Box 5
: "A Comprehensive TALEN-Based Knockout Library for Generating Human-Induced Pluripotent Stem Cell-Based Models for Cardiovascular Diseases." dans: Circulation research, Vol. 120, Issue 10, pp. 1561-1571, (2017) (PubMed).: "TBX5 mutations contribute to early-onset atrial fibrillation in Chinese and Caucasians." dans: Cardiovascular research, Vol. 109, Issue 3, pp. 442-50, (2016) (PubMed).
: "Single-Cell Expression Profiling Reveals a Dynamic State of Cardiac Precursor Cells in the Early Mouse Embryo." dans: PLoS ONE, Vol. 10, Issue 10, pp. e0140831, (2015) (PubMed).
: "Kctd10 regulates heart morphogenesis by repressing the transcriptional activity of Tbx5a in zebrafish." dans: Nature communications, Vol. 5, pp. 3153, (2014) (PubMed).
: "Holt-Oram syndrome with intermediate atrioventricular canal defect, and aortic coarctation: functional characterization of a de novo TBX5 mutation." dans: American journal of medical genetics. Part A, Vol. 164A, Issue 6, pp. 1419-24, (2014) (PubMed).
: "Directing cardiomyogenic differentiation of human pluripotent stem cells by plasmid-based transient overexpression of cardiac transcription factors." dans: Stem cells and development, Vol. 22, Issue 7, pp. 1112-25, (2013) (PubMed).
: "Phenanthrene exposure causes cardiac arrhythmia in embryonic zebrafish via perturbing calcium handling." dans: Aquatic toxicology (Amsterdam, Netherlands), Vol. 142-143, pp. 26-32, (2013) (PubMed).
: "Directed cardiomyocyte differentiation from human pluripotent stem cells by modulating Wnt/β-catenin signaling under fully defined conditions." dans: Nature protocols, Vol. 8, Issue 1, pp. 162-75, (2012) (PubMed).
: "Induction of apoptosis and inhibition of cell growth by tbx5 knockdown contribute to dysmorphogenesis in Zebrafish embryos." dans: Journal of biomedical science, Vol. 18, pp. 73, (2011) (PubMed).
: "Physical interaction between TBX5 and MEF2C is required for early heart development." dans: Molecular and cellular biology, Vol. 29, Issue 8, pp. 2205-18, (2009) (PubMed).
Synonymes et noms alternatifs relatifs à T-Box 5
T-box 5 (TBX5), T-box 5 (tbx5), T-box 5 L homeolog (tbx5.L), T-box 5 (Tbx5), T-box 5a (tbx5a), HOS, tbx-5, TBX5, tbx5, tbx5.1, xtbx-5, xtbx5, zf-tbx5, zTbx5Protein level used designations for T-Box 5
- T-box 5
- T-box protein 5
- T-box transcription factor 5
- T-box transcription factor TBX5
- T-box transcription factor TBX5-like
- t-box transcription factor TBX5-like
- T-box gene 5
- T-box gene 5.1
- T-box transcription factor TBX5-A
- etID310031.5
- heartstrings
- hst
- zftbx5a
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