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TBXAS1 Produits

(thromboxane A Synthase 1 (Platelet) (TBXAS1))

Catégories

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. However, this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity. This endoplasmic reticulum membrane protein catalyzes the conversion of prostglandin H2 to thromboxane A2, a potent vasoconstrictor and inducer of platelet aggregation. The enzyme plays a role in several pathophysiological processes including hemostasis, cardiovascular disease, and stroke. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008].

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Catégories TBXAS1 en vedette

TBXAS1 Anticorps

High quality antibodies with extensive validation data.

TBXAS1 Kits ELISA

Reliable ELISA kits for a wide range of species.

TBXAS1 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

TBXAS1 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Rat
Application WB, IHC, IF, IHC (p), FACS
Validations
  • (8)
N° du produit ABIN1501382
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC, IF, IHC (p), FACS
Validations
  • (6)
N° du produit ABIN1501383
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human, Mouse
Application WB, ELISA, IHC (p)
Validations
  • (3)
N° du produit ABIN752623
Quantité 100 μL
Fiche technique Fiche technique

TBXAS1 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6970643
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6970644
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Guinea Pig
Analytical Method Quantitative
Validations
N° du produit ABIN777809
Quantité 96 tests
Fiche technique Fiche technique

TBXAS1 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1322310
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7417933
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
N° du produit ABIN3097044
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits TBXAS1

Valkonen, Holopainen, Colas, Impola, Dalli, Käkelä, Siljander, Laitinen: "Lipid mediators in platelet concentrate and extracellular vesicles: Molecular mechanisms from membrane glycerophospholipids to bioactive molecules." dans: Biochimica et biophysica acta. Molecular and cell biology of lipids, Vol. 1864, Issue 8, pp. 1168-1182, (2019) (PubMed).

Minami, Takigawa, Kato, Kudo, Isozaki, Hashida, Harada, Ochi, Fujii, Kubo, Ohashi, Sato, Tanaka, Hotta, Tabata, Toyooka, Tanimoto, Kiura: "Downregulation of TBXAS1 in an iron-induced malignant mesothelioma model." dans: Cancer science, Vol. 106, Issue 10, pp. 1296-302, (2015) (PubMed).

Meling, Zelasko, Kambalyal, Roy, Das: "Functional role of the conserved i-helix residue I346 in CYP5A1-Nanodiscs." dans: Biophysical chemistry, Vol. 200-201, pp. 34-40, (2015) (PubMed).

Huang, Chu, Jiang, Chen, Zhang, Zeng: "Glycyrrhizin suppresses lung adenocarcinoma cell growth through inhibition of thromboxane synthase." dans: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, Vol. 33, Issue 2, pp. 375-88, (2014) (PubMed).

Das, Varma, Mularczyk, Meling: "Functional investigations of thromboxane synthase (CYP5A1) in lipid bilayers of nanodiscs." dans: Chembiochem : a European journal of chemical biology, Vol. 15, Issue 6, pp. 892-9, (2014) (PubMed).

Huang, Chu, Huang, Chen, Jiang, Zhang, Zeng: "18β-Glycyrrhetinic acid suppresses cell proliferation through inhibiting thromboxane synthase in non-small cell lung cancer." dans: PLoS ONE, Vol. 9, Issue 4, pp. e93690, (2014) (PubMed).

Synonymes et noms alternatifs relatifs à TBXAS1

thromboxane-A synthase (PTRG_00454), thromboxane-A synthase (PTRG_06796), Thromboxane-A synthase (thas), thromboxane A synthase 1 (TBXAS1), thromboxane A synthase 1 (platelet) (tbxas1), thromboxane A synthase 1, platelet (Tbxas1), thromboxane A synthase 1 (Tbxas1), BDPLT14, CYP5, CYP5A1, GHOSAL, TBXAS1, thas, THAS, TS, TXAS, TXS, wu:fk19d08, zgc:136708

Protein level used designations for TBXAS1

  • thromboxane-A synthase
  • Thromboxane-A synthase
  • thromboxane A synthase 1 (platelet, cytochrome P450, family 5, subfamily A)
  • thromboxane A synthase 1 (platelet)
  • thromboxane-A synthase-like
  • TXA synthase
  • cytochrome P450 5A1
  • cytochrome P450, family 5, subfamily A, polypeptide 1
  • platelet, cytochrome P450, subfamily V
  • TXS
  • thromboxane A synthase 1, platelet
  • ThromboxA ane synthase 1
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