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TDO2 Produits

(Tryptophan 2,3-Dioxygenase (TDO2))

Catégories

This gene encodes a heme enzyme that plays a critical role in tryptophan metabolism by catalyzing the first and rate-limiting step of the kynurenine pathway. Increased activity of the encoded protein and subsequent kynurenine production may also play a role in cancer through the suppression of antitumor immune responses, and single nucleotide polymorphisms in this gene may be associated with autism. [provided by RefSeq, Feb 2012].

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Catégories TDO2 en vedette

TDO2 Anticorps

High quality antibodies with extensive validation data.

TDO2 Kits ELISA

Reliable ELISA kits for a wide range of species.

TDO2 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

TDO2 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC, IHC (p)
Validations
  • (10)
N° du produit ABIN1501352
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Dog, Human, Pig
Application WB, IHC
Validations
  • (7)
N° du produit ABIN2782334
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB
Validations
  • (1)
  • (3)
N° du produit ABIN520811
Quantité 50 μg
Fiche technique Fiche technique

TDO2 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6970915
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6960224
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method Quantitative Competition ELISA
Validations
N° du produit ABIN511131
Quantité 96 tests
Fiche technique Fiche technique

TDO2 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1322430
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1322432
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (2)
N° du produit ABIN2733390
Quantité 20 μg
Fiche technique Fiche technique

Dernières publications sur nos produits TDO2

Hao, Huang, Feng, Li, Wang, Wang, Wu, Wan, Zhang, Zhang: "Non-NF2 mutations have a key effect on inhibitory immune checkpoints and tumor pathogenesis in skull base meningiomas." dans: Journal of neuro-oncology, Vol. 144, Issue 1, pp. 11-20, (2019) (PubMed).

Wang, Do, Liu, Wang, Qu, Ke, Luo, Tang, Tang, Hu, Anderson, Liu, Gao: "Functional role of kynurenine and aryl hydrocarbon receptor axis in chronic rhinosinusitis with nasal polyps." dans: The Journal of allergy and clinical immunology, Vol. 141, Issue 2, pp. 586-600.e6, (2018) (PubMed).

Woodling, Colas, Wang, Minhas, Panchal, Liang, Mhatre, Brown, Ko, Zagol-Ikapitte, van der Hart, Khroyan, Chuluun, Priyam, Milne, Rassoulpour, Boutaud, Manning-Boğ, Heller, Andreasson: "Cyclooxygenase inhibition targets neurons to prevent early behavioural decline in Alzheimer's disease model mice." dans: Brain : a journal of neurology, Vol. 139, Issue Pt 7, pp. 2063-81, (2016) (PubMed).

Guastella, Michelhaugh, Klinger, Kupsky, Polin, Muzik, Juhász, Mittal: "Tryptophan PET Imaging of the Kynurenine Pathway in Patient-Derived Xenograft Models of Glioblastoma." dans: Molecular imaging, Vol. 15, (2016) (PubMed).

Novikov, Wang, Stanford, Parks, Ramirez-Cardenas, Landesman, Laklouk, Sarita-Reyes, Gusenleitner, Li, Monti, Manteiga, Lee, Sherr: "An Aryl Hydrocarbon Receptor-Mediated Amplification Loop That Enforces Cell Migration in ER-/PR-/Her2- Human Breast Cancer Cells." dans: Molecular pharmacology, Vol. 90, Issue 5, pp. 674-688, (2016) (PubMed).

Bosnyák, Kamson, Guastella, Varadarajan, Robinette, Kupsky, Muzik, Michelhaugh, Mittal, Juhász: "Molecular imaging correlates of tryptophan metabolism via the kynurenine pathway in human meningiomas." dans: Neuro-oncology, Vol. 17, Issue 9, pp. 1284-92, (2015) (PubMed).

Xiao, Li, Jones-Brando, Yolken: "Abnormalities of neurotransmitter and neuropeptide systems in human neuroepithelioma cells infected by three Toxoplasma strains." dans: Journal of neural transmission (Vienna, Austria : 1996), Vol. 120, Issue 12, pp. 1631-9, (2013) (PubMed).

Ohira, Hagihara, Toyama, Takao, Kanai, Funakoshi, Nakamura, Miyakawa: "Expression of tryptophan 2,3-dioxygenase in mature granule cells of the adult mouse dentate gyrus." dans: Molecular brain, Vol. 3, Issue 1, pp. 26, (2010) (PubMed).

Synonymes et noms alternatifs relatifs à TDO2

tryptophan 2,3-dioxygenase b (tdo2b), tryptophan 2,3-dioxygenase (tdo2), tryptophan 2,3-dioxygenase (TDO2), tryptophan 2,3-dioxygenase (MADE_02822), tryptophan 2,3-dioxygenase (CtCNB1_3657), tryptophan 2,3-dioxygenase a (tdo2a), tryptophan 2,3-dioxygenase (CNC04830), tryptophan 2,3-dioxygenase (tdo), tryptophan 2,3-dioxygenase (Mrub_2119), tryptophan 2,3-dioxygenase (Deipr_2235), tryptophan 2,3-dioxygenase (Acav_1166), tryptophan 2,3-dioxygenase (Mesop_4278), tryptophan 2,3-dioxygenase (Tdo2), tryptophan 2,3-dioxygenase L homeolog (tdo2.L), AA407491, chky, DDBDRAFT_0190495, DDBDRAFT_0231363, DDB_0190495, DDB_0231363, fb62b10, fi30d08, TDO, Tdo, Tdo2, TDO2, tdo2, tdo2l, TO, TPH2, TRPO, wu:fb62b10, wu:fi30d08, zgc:63488, zgc:103693

Protein level used designations for TDO2

  • TDO-B
  • TO-B
  • TRPO-B
  • tryptamin 2,3-dioxygenase B
  • tryptophan 2,3-dioxygenase B
  • tryptophan 2,3-dioxygenase, like
  • tryptophan oxygenase B
  • tryptophan pyrrolase B
  • tryptophanase B
  • TDO
  • TO
  • TRPO
  • tryptamin 2,3-dioxygenase
  • tryptophan oxygenase
  • tryptophan pyrrolase
  • tryptophanase
  • tryptophan 2,3-dioxygenase
  • TDO-A
  • TO-A
  • TRPO-A
  • tryptamin 2,3-dioxygenase A
  • tryptophan 2,3-dioxygenase A
  • tryptophan oxygenase A
  • tryptophan pyrrolase A
  • tryptophanase A
  • tdo variant1
  • tdo variant2
  • tryptophan-2,3-dioxygenase
  • tryptophan-23-dioxygenase
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