TERT Produits
(Telomerase Reverse Transcriptase (TERT))
Catégories
Telomerase is a ribonucleoprotein polymerase that maintains telomere ends by addition of the telomere repeat TTAGGG. The enzyme consists of a protein component with reverse transcriptase activity, encoded by this gene, and an RNA component which serves as a template for the telomere repeat. Telomerase expression plays a role in cellular senescence, as it is normally repressed in postnatal somatic cells resulting in progressive shortening of telomeres. Deregulation of telomerase expression in somatic cells may be involved in oncogenesis. Studies in mouse suggest that telomerase also participates in chromosomal repair, since de novo synthesis of telomere repeats may occur at double-stranded breaks. Alternatively spliced variants encoding different isoforms of telomerase reverse transcriptase have been identified\; the full-length sequence of some variants has not been determined. Alternative splicing at this locus is thought to be one mechanism of regulation of telomerase activity. [provided by RefSeq, Jul 2008].
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Catégories TERT en vedette
TERT Anticorps
High quality antibodies with extensive validation data.
TERT Kits ELISA
Reliable ELISA kits for a wide range of species.
TERT Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
TERT recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC, IP, FM
Validations
- (20)
- (8)
N° du produit
ABIN6655270
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
- (3)
- (5)
N° du produit
ABIN726650
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC, FACS, ICC
Validations
- (6)
N° du produit
ABIN5542472
Quantité
100 μL
Fiche technique
Fiche technique
TERT recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
N° du produit
ABIN6962962
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
N° du produit
ABIN6961943
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
N° du produit
ABIN6973670
Quantité
96 tests
Fiche technique
Fiche technique
TERT recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN7125334
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7396088
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7404335
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits TERT
: "Maternal neglect results in reduced telomerase activity and increased oxidative load in rats." dans: Stress (Amsterdam, Netherlands), pp. 1-5, (2020) (PubMed).: "Beneficial Effects of Fermented Papaya Preparation (FPP®) Supplementation on Redox Balance and Aging in a Mouse Model." dans: Antioxidants (Basel, Switzerland), Vol. 9, Issue 2, (2020) (PubMed).
: "Ganoderic Acid D Protects Human Amniotic Mesenchymal Stem Cells against Oxidative Stress-Induced Senescence through the PERK/NRF2 Signaling Pathway." dans: Oxidative medicine and cellular longevity, Vol. 2020, pp. 8291413, (2020) (PubMed).
: "Telomerase Reverse Transcriptase (TERT) Expression, Telomerase Activity, and Expression of Matrix Metalloproteinases (MMP)-1/-2/-9 in Feline Oral Squamous Cell Carcinoma Cell Lines Associated With ..." dans: Frontiers in veterinary science, Vol. 7, pp. 148, (2020) (PubMed).
: "Anti-senescence role of heterozygous fumarate hydratase gene knockout in rat lung fibroblasts in vitro." dans: Aging, Vol. 11, Issue 2, pp. 573-589, (2020) (PubMed).
: "Stabilization of Reversed Replication Forks by Telomerase Drives Telomere Catastrophe." dans: Cell, Vol. 172, Issue 3, pp. 439-453.e14, (2019) (PubMed).
: "Telomerase level increase is related to n-3 polyunsaturated fatty acid efficacy in first episode schizophrenia: Secondary outcome analysis of the OFFER randomized clinical trial." dans: Progress in neuro-psychopharmacology & biological psychiatry, Vol. 83, pp. 142-148, (2019) (PubMed).
: "Generation of an immortalized human choroid endothelial cell line (iChEC-1) using an endothelial cell specific promoter." dans: Microvascular research, Vol. 123, pp. 50-57, (2019) (PubMed).
: "Prognostic impact and concordance of TERT promoter mutation and protein expression in matched primary and metastatic cutaneous melanoma." dans: British journal of cancer, Vol. 118, Issue 1, pp. 98-105, (2019) (PubMed).
: "Increased expression of NAF1 contributes to malignant phenotypes of glioma cells through promoting protein synthesis and associates with poor patient survival." dans: Oncogenesis, Vol. 8, Issue 4, pp. 25, (2019) (PubMed).
Synonymes et noms alternatifs relatifs à TERT
telomerase reverse transcriptase (TERT), Telomerase Reverse Transcriptase (trt-1), telomerase reverse transcriptase (Tert), telomerase reverse transcriptase (tert), Tertp (TERT), telomerase reverse transcriptase (CMU_003490), telomerase reverse transcriptase (VDBG_04487), Telomerase catalytic subunit (GL50803_16225), telomerase reverse transcriptase L homeolog (tert.L), ATTERT, chTERT, CMM9, DKCA2, DKCB4, EST2, est2, F5E19.190, F5E19_190, hEST2, hTRT, PFBMFT1, TCS1, tcs1, telomerase, telomerase reverse transcriptase, Tert, tert, tert-A, TP2, tp2, TR, TRT, trt, xTERTProtein level used designations for TERT
- telomerase catalytic subunit
- telomerase-associated protein 2
- Telomerase Reverse Transcriptase family member (trt-1)
- telomerase reverse transcriptase
- hypothetical protein
- telomerase reverse transcriptase beta
- Telomerase catalytic subunit
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