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TFAM Produits

(Transcription Factor A, Mitochondrial (TFAM))

Catégories

This gene encodes a key mitochondrial transcription factor containing two high mobility group motifs. The encoded protein also functions in mitochondrial DNA replication and repair. Sequence polymorphisms in this gene are associated with Alzheimer's and Parkinson's diseases. There are pseudogenes for this gene on chromosomes 6, 7, and 11. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012].

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Catégories TFAM en vedette

TFAM Anticorps

High quality antibodies with extensive validation data.

TFAM Kits ELISA

Reliable ELISA kits for a wide range of species.

TFAM Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

TFAM recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit
Application WB
Validations
  • (10)
  • (6)
N° du produit ABIN2777277
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Mouse
Application WB, IHC, IP, ICC
Validations
  • (6)
N° du produit ABIN7438793
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC (p), FACS
Validations
  • (6)
N° du produit ABIN654229
Quantité 400 μL
Fiche technique Fiche technique

TFAM recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
N° du produit ABIN6960059
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6960058
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN4973162
Quantité 96 tests
Fiche technique Fiche technique

TFAM recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN7125440
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN2132113
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7408864
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits TFAM

Yamanishi, Doe, Mukai, Ikubo, Hashimoto, Uwa, Sumida, El-Darawish, Gamachi, Li, Kuwahara-Otani, Maeda, Watanabe, Hayakawa, Yamanishi, Matsuyama, Yagi, Okamura, Matsunaga: "Interleukin-18-deficient mice develop hippocampal abnormalities related to possible depressive-like behaviors." dans: Neuroscience, Vol. 408, pp. 147-160, (2019) (PubMed).

Manczak, Kandimalla, Yin, Reddy: "Mitochondrial division inhibitor 1 reduces dynamin-related protein 1 and mitochondrial fission activity." dans: Human molecular genetics, Vol. 28, Issue 2, pp. 177-199, (2019) (PubMed).

Kamel, Abdelkader, Abd El-Rahman, Emara, Zaki, Khattab: "Stimulation of ACE2/ANG(1-7)/Mas Axis by Diminazene Ameliorates Alzheimer's Disease in the D-Galactose-Ovariectomized Rat Model: Role of PI3K/Akt Pathway." dans: Molecular neurobiology, Vol. 55, Issue 10, pp. 8188-8202, (2018) (PubMed).

Widdrington, Gomez-Duran, Pyle, Ruchaud-Sparagano, Scott, Baudouin, Rostron, Lovat, Chinnery, Simpson: "Exposure of Monocytic Cells to Lipopolysaccharide Induces Coordinated Endotoxin Tolerance, Mitochondrial Biogenesis, Mitophagy, and Antioxidant Defenses." dans: Frontiers in immunology, Vol. 9, pp. 2217, (2018) (PubMed).

Huang, Wang, Yang, Chiou, Tan, Lin, Huang: "Gastrodia elata alleviates mutant huntingtin aggregation through mitochondrial function and biogenesis mediation." dans: Phytomedicine : international journal of phytotherapy and phytopharmacology, Vol. 39, pp. 75-84, (2018) (PubMed).

Dlasková, Engstová, Špaček, Kahancová, Pavluch, Smolková, Špačková, Bartoš, Hlavatá, Ježek: "3D super-resolution microscopy reflects mitochondrial cristae alternations and mtDNA nucleoid size and distribution." dans: Biochimica et biophysica acta. Bioenergetics, Vol. 1859, Issue 9, pp. 829-844, (2018) (PubMed).

Yang, Li, Zhu, Cao, Kroemer, Zeh, Tang, Kang: "TFAM is a novel mediator of immunogenic cancer cell death." dans: Oncoimmunology, Vol. 7, Issue 6, pp. e1431086, (2018) (PubMed).

Yan, Liu, Guan, Guo: "Deferoxamine ameliorates adipocyte dysfunction by modulating iron metabolism in ob/ob mice." dans: Endocrine connections, Vol. 7, Issue 4, pp. 604-616, (2018) (PubMed).

Wu, Zhao, Xiao, Peng, Chen, He: "Roles of mitochondrial transcription factor A and microRNA‑590‑3p in the development of colon cancer." dans: Molecular medicine reports, Vol. 14, Issue 6, pp. 5475-5480, (2017) (PubMed).

Mastrocola, Penna, Tullio, Femminò, Nigro, Chiazza, Serpe, Collotta, Alloatti, Cocco, Bertinaria, Pagliaro, Aragno, Collino: "Pharmacological Inhibition of NLRP3 Inflammasome Attenuates Myocardial Ischemia/Reperfusion Injury by Activation of RISK and Mitochondrial Pathways." dans: Oxidative medicine and cellular longevity, Vol. 2016, pp. 5271251, (2017) (PubMed).

Synonymes et noms alternatifs relatifs à TFAM

transcription factor A, mitochondrial (TFAM), transcription factor A, mitochondrial L homeolog (tfam.L), transcription factor A, mitochondrial (tfam), transcription factor A, mitochondrial (Tfam), AI661103, Hmgts, MGC153358, mttf1, MTTF1, mttfa, MTTFA, mtTFA, Mttfa, mttfa-A, tcf6, TCF6, tcf6l1, TCF6L1, tcf6l2, TCF6L2, tcf6l3, TCF6L3, tsHMG, xl-mtTFA, zgc:153358

Protein level used designations for TFAM

  • transcription factor A, mitochondrial
  • HMG box mitochondrial transcription factor
  • mitochondrial transcription factor 1
  • mitochondrial transcription factor A
  • transcription factor 6
  • transcription factor 6-like 1
  • transcription factor 6-like 2 (mitochondrial transcription factor)
  • transcription factor 6-like 3
  • mtTFA
  • transcription factor 6-like 2
  • TS-HMG
  • testis-specific HMG-box protein m-tsHMG
  • testis-specific high mobility group protein
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