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TGF-beta Produits

(TGF-beta (TGFb))
This gene encodes a member of the transforming growth factor beta (TGFB) family of cytokines, which are multifunctional peptides that regulate proliferation, differentiation, adhesion, migration, and other functions in many cell types. Many cells have TGFB receptors, and the protein positively and negatively regulates many other growth factors. The secreted protein is cleaved into a latency-associated peptide (LAP) and a mature TGFB1 peptide, and is found in either a latent form composed of a TGFB1 homodimer, a LAP homodimer, and a latent TGFB1-binding protein, or in an active form composed of a TGFB1 homodimer. The mature peptide may also form heterodimers with other TGFB family members. This gene is frequently upregulated in tumor cells, and mutations in this gene result in Camurati-Engelmann disease.[provided by RefSeq, Oct 2009].

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Catégories TGF-beta en vedette

TGF-beta Anticorps

High quality antibodies with extensive validation data.

TGF-beta Kits ELISA

Reliable ELISA kits for a wide range of species.

TGF-beta Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

TGF-beta recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Mouse, Rabbit, Rat, Sheep
Application WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
  • (2)
N° du produit ABIN707021
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human, Mammalian, Mouse, Rabbit, Rat
Application WB, ELISA, IHC (p)
Validations
  • (3)
  • (1)
N° du produit ABIN2476753
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Cow, Dog, Hamster, Human, Monkey, Mouse, Rat
Application ELISA, Func, D, ELISA (Capture)
Validations
  • (1)
N° du produit ABIN6940723
Quantité 100 μg
Fiche technique Fiche technique

TGF-beta recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Monkey
Analytical Method Quantitative Competition ELISA
Validations
N° du produit ABIN1059453
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Sheep
Analytical Method Quantitative Competition ELISA
Validations
N° du produit ABIN1059454
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Chicken
Analytical Method Competition ELISA
Validations
N° du produit ABIN1059452
Quantité 96 tests
Fiche technique Fiche technique

TGF-beta recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Hi-5 Cells
Validations
N° du produit ABIN2469123
Quantité 0.002 mg
Fiche technique Fiche technique

Dernières publications sur nos produits TGF-beta

Baumeier, Escher, Aleshcheva, Pietsch, Schultheiss: "Plasminogen activator inhibitor-1 reduces cardiac fibrosis and promotes M2 macrophage polarization in inflammatory cardiomyopathy." dans: Basic research in cardiology, Vol. 116, Issue 1, pp. 1, (2021) (PubMed).

Playford, Cattell, Marchbank: "Marked variability in bioactivity between commercially available bovine colostrum for human use; implications for clinical trials." dans: PLoS ONE, Vol. 15, Issue 6, pp. e0234719, (2020) (PubMed).

Sunil Gowda, Rajasowmiya, Vadivel, Banu Devi, Celestin Jerald, Marimuthu, Devipriya: "Gallic acid-coated sliver nanoparticle alters the expression of radiation-induced epithelial-mesenchymal transition in non-small lung cancer cells." dans: Toxicology in vitro : an international journal published in association with BIBRA, Vol. 52, pp. 170-177, (2018) (PubMed).

Xia, Ren, Zhu, Yu, Zhang, Sun, Zhao, Chen: "Downregulation of miR-145 in venous malformations: Its association with disorganized vessels and sclerotherapy." dans: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, Vol. 100, pp. 126-131, (2017) (PubMed).

Chen, Ren, Zhang, Sun, Wang, Li, Zhang, Zhao: "Disorganized vascular structures in sporadic venous malformations: a possible correlation with balancing effect between Tie2 and TGF-β." dans: Scientific reports, Vol. 4, pp. 5457, (2016) (PubMed).

Polichnowski, Lan, Geng, Griffin, Venkatachalam, Bidani: "Severe renal mass reduction impairs recovery and promotes fibrosis after AKI." dans: Journal of the American Society of Nephrology : JASN, Vol. 25, Issue 7, pp. 1496-507, (2014) (PubMed).

Bob, Gluhovschi, Herman, Petrica, Bozdog, Gluhovschi, Velciov, Gadalean, Timar, Potencz, Dema, Schiller: "Immunohistochemical study of tubular epithelial cells and vascular endothelial cells in glomerulonephritis." dans: Renal failure, Vol. 36, Issue 8, pp. 1208-14, (2014) (PubMed).

Moore, Sawyer, Charokopos, Skokos, Kyriakides: "Loss of monocyte chemoattractant protein-1 alters macrophage polarization and reduces NF?B activation in the foreign body response." dans: Acta biomaterialia, Vol. 11, pp. 37-47, (2014) (PubMed).

Geng, Lan, Singha, Gilchrist, Weinreb, Violette, Weinberg, Saikumar, Venkatachalam: "Lysophosphatidic acid increases proximal tubule cell secretion of profibrotic cytokines PDGF-B and CTGF through LPA2- and G?q-mediated Rho and ?v?6 integrin-dependent activation of TGF-?." dans: The American journal of pathology, Vol. 181, Issue 4, pp. 1236-49, (2012) (PubMed).

Mortarini, Vegetti, Molla, Arienti, Ravagnani, Maurichi, Patuzzo, Santinami, Anichini: "Impaired STAT phosphorylation in T cells from melanoma patients in response to IL-2: association with clinical stage." dans: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 15, Issue 12, pp. 4085-94, (2009) (PubMed).

Synonymes et noms alternatifs relatifs à TGF-beta

transforming growth factor beta 1 (TGFB1), transforming growth factor beta-1 (TGFB1), transforming growth factor beta 1 (Tgfb1), transforming growth factor, beta 1 (Tgfb1), CED, DPD1, LAP, TGF-beta, TGF-BETA-1, TGF-beta1, TGFB, Tgfb, Tgfb-1, TGFbeta, TGFbeta1

Protein level used designations for TGF-beta

  • TGF-beta 1 protein
  • TGF-beta-1
  • latency-associated peptide
  • transforming growth factor beta-1
  • transforming growth factor, beta 1 (Camurati-Engelmann disease)
  • transforming growth factor-beta 1
  • transforming growth factor beta 1
  • transforming growth factor-beta
  • transforming growth factor beta1
  • transforming growth factor-beta-1
  • TGF-beta 1
  • regulatory protein
  • transforming growth factor, beta-1
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