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TGFBR2 Produits

(Transforming Growth Factor, beta Receptor II (70/80kDa) (TGFBR2))
This gene encodes a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. The encoded protein is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with another receptor protein, and binds TGF-beta. This receptor/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation. Mutations in this gene have been associated with Marfan Syndrome, Loeys-Deitz Aortic Aneurysm Syndrome, and the development of various types of tumors. Alternatively spliced transcript variants encoding different isoforms have been characterized. [provided by RefSeq, Jul 2008].

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Catégories TGFBR2 en vedette

TGFBR2 Anticorps

High quality antibodies with extensive validation data.

TGFBR2 Kits ELISA

Reliable ELISA kits for a wide range of species.

TGFBR2 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

TGFBR2 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Mouse
Application WB, IF, IHC (p)
Validations
  • (1)
  • (7)
N° du produit ABIN655799
Quantité 400 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC, IF
Validations
  • (6)
N° du produit ABIN6149084
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Cow, Human, Mouse, Rabbit, Rat
Application WB, ELISA, IF (cc), IF (p), IHC (p), FACS, IHC (fro)
Validations
  • (4)
  • (3)
N° du produit ABIN725225
Quantité 100 μL
Fiche technique Fiche technique

TGFBR2 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
N° du produit ABIN6960105
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6970806
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6970807
Quantité 96 tests
Fiche technique Fiche technique

TGFBR2 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (4)
N° du produit ABIN7275717
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (4)
N° du produit ABIN7275719
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (3)
N° du produit ABIN7275718
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits TGFBR2

Thepmalee, Panya, Junking, Chieochansin, Yenchitsomanus: "Inhibition of IL-10 and TGF-β receptors on dendritic cells enhances activation of effector T-cells to kill cholangiocarcinoma cells." dans: Human vaccines & immunotherapeutics, Vol. 14, Issue 6, pp. 1423-1431, (2019) (PubMed).

Lou, Li, Zhou, Chen, Weng, Zou, Tang, Bu, Yin: "(+)-Isobicyclogermacrenal and spathulenol from Aristolochia yunnanensis alleviate cardiac fibrosis by inhibiting transforming growth factor β/small mother against decapentaplegic signaling pathway." dans: Phytotherapy research : PTR, Vol. 33, Issue 1, pp. 214-223, (2019) (PubMed).

Lam, van den Bosch, Wegrzyn, Parker, Ibrahim, Slowski, Chang, Martinez-Høyer, Condorelli, Boldin, Deng, Umlandt, Fuller, Karsan: "miR-143/145 differentially regulate hematopoietic stem and progenitor activity through suppression of canonical TGFβ signaling." dans: Nature communications, Vol. 9, Issue 1, pp. 2418, (2018) (PubMed).

Zhang, Wang, Xue, Lai, Ji, Jin, Chen: "Nicousamide protects kidney podocyte by inhibiting the TGFβ receptor II phosphorylation and AGE-RAGE signaling." dans: American journal of translational research, Vol. 9, Issue 1, pp. 115-125, (2017) (PubMed).

Olsen, Skjærvik, Størdal, Sundan, Holien: "TGF-β contamination of purified recombinant GDF15." dans: PLoS ONE, Vol. 12, Issue 11, pp. e0187349, (2017) (PubMed).

Jiang, Wei, Zhu, Wu, Wang: "Aspirin Inhibits LPS-Induced Expression of PI3K/Akt, ERK, NF-κB, CX3CL1, and MMPs in Human Bronchial Epithelial Cells." dans: Inflammation, Vol. 39, Issue 2, pp. 643-50, (2017) (PubMed).

Choi, Ahn, Kim, Bae, Lee, You, Cho: "TGF-β Signaling Regulates Cementum Formation through Osterix Expression." dans: Scientific reports, Vol. 6, pp. 26046, (2016) (PubMed).

Wu, Majeed, Evans, Camus, Wong, Schollmeier, Park, Muppidi, Reboldi, Parham, Cyster, Brodsky: "Clathrin light chains' role in selective endocytosis influences antibody isotype switching." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 113, Issue 35, pp. 9816-21, (2016) (PubMed).

Boyan, Hyzy, Pan, Scott, Coutts, Healey, Schwartz: "24R,25-Dihydroxyvitamin D3 Protects against Articular Cartilage Damage following Anterior Cruciate Ligament Transection in Male Rats." dans: PLoS ONE, Vol. 11, Issue 8, pp. e0161782, (2016) (PubMed).

Lewis, Wehrens, Labarta-Bajo, Streeck, Zuniga: "TGF-β receptor maintains CD4 T helper cell identity during chronic viral infections." dans: The Journal of clinical investigation, Vol. 126, Issue 10, pp. 3799-3813, (2016) (PubMed).

Synonymes et noms alternatifs relatifs à TGFBR2

transforming growth factor beta receptor 2 (TGFBR2), transforming growth factor, beta receptor II (Tgfbr2), transforming growth factor, beta receptor 2 (Tgfbr2), transforming growth factor beta receptor 2b (tgfbr2b), transforming growth factor beta receptor 2 (Tgfbr2), 1110020H15Rik, AAT3, AU042018, cb537, DNIIR, FAA3, LDS1B, LDS2B, MFS2, RIIC, RIIDN, TAAD2, TBETA-RII, TbetaR-II, TbetaRII, TBR-II, TGF-beta 2, TGFbeta-RII, TGFBR2, tgfbr2, Tgfbr2T, TGFBRII, TGFR-2, wu:fj05c10, zgc:110498

Protein level used designations for TGFBR2

  • TGF-beta receptor type II
  • TGF-beta receptor type-2
  • TGF-beta type II receptor
  • TGFR-2
  • tbetaR-II
  • transforming growth factor-beta receptor type II
  • transforming growth factor-beta type II receptor
  • TGF-beta receptor type IIB
  • transforming growth factor beta receptor type IIC
  • TGF-beta receptor II
  • transforming growth factor, beta receptor II (70/80kDa)
  • transforming growth factor beta type II receptor
  • transforming growth factor, beta receptor II
  • transforming growth factor beta receptor 2
  • TGF beta receptor type II
  • TGF-beta receptor type-2-like
  • transforming growth factor beta receptor type II
  • transforming growth factor beta, receptor 2
  • transforming growth factor, beta receptor 2
  • transforming growth factor, beta receptor IIT
  • transforming growth factor-b type II receptor
  • TGF-beta receptor 2
  • transforming growth factor-beta receptor 2
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