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Thyroid Hormone Receptor, beta Produits

(Thyroid Hormone Receptor, beta (THRB))
The protein encoded by this gene is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of thyroid hormone. Knockout studies in mice suggest that the different receptors, while having certain extent of redundancy, may mediate different functions of thyroid hormone. Mutations in this gene are known to be a cause of generalized thyroid hormone resistance (GTHR), a syndrome characterized by goiter and high levels of circulating thyroid hormone (T3-T4), with normal or slightly elevated thyroid stimulating hormone (TSH). Several alternatively spliced transcript variants encoding the same protein have been observed for this gene. [provided by RefSeq, Jul 2008].

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Catégories Thyroid Hormone Receptor, beta en vedette

Thyroid Hormone Receptor, beta Anticorps

High quality antibodies with extensive validation data.

Thyroid Hormone Receptor, beta Kits ELISA

Reliable ELISA kits for a wide range of species.

Thyroid Hormone Receptor, beta Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

Thyroid Hormone Receptor, beta recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC, IF, ICC, IHC (p)
Validations
  • (4)
N° du produit ABIN467595
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (3)
N° du produit ABIN7172152
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA
Validations
  • (3)
  • (2)
N° du produit ABIN349600
Quantité 100 μg
Fiche technique Fiche technique

Thyroid Hormone Receptor, beta recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6959962
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Analytical Method Qualitative Cell ELISA
Validations
N° du produit ABIN5648298
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Analytical Method Qualitative DNA-Binding ELISA
Validations
N° du produit ABIN5648643
Quantité 96 tests
Fiche technique Fiche technique

Thyroid Hormone Receptor, beta recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1322721
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7415668
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
N° du produit ABIN3074033
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits Thyroid Hormone Receptor, beta

Fozzatti, Park, Zhao, Willingham, Cheng: "Oncogenic Actions of the Nuclear Receptor Corepressor (NCOR1) in a Mouse Model of Thyroid Cancer." dans: PLoS ONE, Vol. 8, Issue 6, pp. e67954, (2017) (PubMed).

Dong, You, Williams, Wade, Yauk, Thomas Zoeller et al.: "Transient Maternal Hypothyroxinemia Potentiates the Transcriptional Response to Exogenous Thyroid Hormone in the Fetal Cerebral Cortex Before the Onset of Fetal Thyroid Function: A Messenger and ..." dans: Cerebral cortex (New York, N.Y. : 1991), Vol. 25, Issue 7, pp. 1735-45, (2015) (PubMed).

Wang, Wei, Guan, Xue: "Triiodothyronine regulates distribution of thyroid hormone receptors by activating AMP-activated protein kinase in 3T3-L1 adipocytes and induces uncoupling protein-1 expression." dans: Molecular and cellular biochemistry, Vol. 393, Issue 1-2, pp. 247-54, (2014) (PubMed).

Zhao, Zhu, Won Park, Fozzatti, Willingham, Cheng: "Role of TSH in the spontaneous development of asymmetrical thyroid carcinoma in mice with a targeted mutation in a single allele of the thyroid hormone-β receptor." dans: Endocrinology, Vol. 153, Issue 10, pp. 5090-100, (2012) (PubMed).

Mascanfroni, Montesinos, Alamino, Susperreguy, Nicola, Ilarregui, Masini-Repiso, Rabinovich, Pellizas: "Nuclear factor (NF)-kappaB-dependent thyroid hormone receptor beta1 expression controls dendritic cell function via Akt signaling." dans: The Journal of biological chemistry, Vol. 285, Issue 13, pp. 9569-82, (2010) (PubMed).

Iizuka, Endo, Tsubochi, Nokubi, Matsuura, Sohara: "[Massive hemoptysis due to traction bronchiectasis caused by thoracic radiotherapy 23 years earlier]" dans: Kyobu geka. The Japanese journal of thoracic surgery, Vol. 61, Issue 3, pp. 226-9, (2008) (PubMed).

Kim, Park, Baek, Kim, Yoo, Park: "A newly identified insertion mutation in the thyroid hormone receptor-beta gene in a Korean family with generalized thyroid hormone resistance." dans: Journal of Korean medical science, Vol. 22, Issue 3, pp. 560-3, (2007) (PubMed).

Nascimento, Dias, Nunes, Aparício, Ambrosio, Bleicher, Figueira, Santos, de Oliveira Neto, Fischer, Togashi, Craievich, Garratt, Baxter, Webb, Polikarpov: "Structural rearrangements in the thyroid hormone receptor hinge domain and their putative role in the receptor function." dans: Journal of molecular biology, Vol. 360, Issue 3, pp. 586-98, (2006) (PubMed).

Ambrogini, Cuppini, Ferri, Mancini, Ciaroni, Voci, Gerdoni, Gallo: "Thyroid hormones affect neurogenesis in the dentate gyrus of adult rat." dans: Neuroendocrinology, Vol. 81, Issue 4, pp. 244-53, (2005) (PubMed).

Constantinou, Margarity, Valcana: "Region-specific effects of hypothyroidism on the relative expression of thyroid hormone receptors in adult rat brain." dans: Molecular and cellular biochemistry, Vol. 278, Issue 1-2, pp. 93-100, (2005) (PubMed).

Synonymes et noms alternatifs relatifs à Thyroid Hormone Receptor, beta

thyroid hormone receptor beta (THRB), thyroid hormone receptor beta (Thrb), thyroid hormone receptor beta (thrb), thyroid hormone receptor, beta (thrb), thyroid hormone receptor, beta S homeolog (thrb.S), thyroid hormone receptor, beta L homeolog (thrb.L), C-ERBA-2, C-ERBA-BETA, C-erba-beta, c-erbAbeta, CTR BETA 2, ERBA2, fj24f03, GRTH, LOC734147, NR1A2, Nr1a2, PRTH, RATT3REC, T3Rbeta, T3rec, T3R[b], THR, THR1, thrb, THRB, THRB1, Thrb1, THRB2, Thrb2, TR-beta, TR-BETA, trb, TRbeta, TRbeta1, TR[b]1, wu:fj24f03

Protein level used designations for Thyroid Hormone Receptor, beta

  • nuclear receptor subfamily 1 group A member 2
  • oncogene ERBA2
  • thyroid hormone nuclear receptor beta variant 1
  • thyroid hormone receptor beta
  • thyroid hormone receptor, beta (erythroblastic leukemia viral (v-erb-a) oncogene homolog 2, avian)
  • TR beta
  • c-erbA-2
  • c-erbA-beta
  • TRbeta1
  • thyroid hormone receptor beta 1
  • thyroid hormone receptor beta 2
  • thyroid hormone receptor beta-1
  • beta-thyroid hormone receptor
  • thyroid hormone receptor beta isoform
  • TRbeta2Delta
  • thyroid hormone receptor beta 3
  • thyroid hormone receptor beta2delta
  • thyroid hormone receptor, beta (avian erythroblastic leukemia viral (v-erb-a) oncogene homolog 2)
  • thyroid hormone receptor beta2
  • TRbetaB
  • nuclear receptor subfamily 1 group A member 2-B
  • thyroid hormone receptor beta-B
  • TRbetaA
  • nuclear receptor subfamily 1 group A member 2-A
  • xTR
  • LOW QUALITY PROTEIN: thyroid hormone receptor beta
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