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TIA1 Produits

(TIA1 Cytotoxic Granule-Associated RNA Binding Protein (TIA1))

Catégories

The product encoded by this gene is a member of a RNA-binding protein family and possesses nucleolytic activity against cytotoxic lymphocyte (CTL) target cells. It has been suggested that this protein may be involved in the induction of apoptosis as it preferentially recognizes poly(A) homopolymers and induces DNA fragmentation in CTL targets. The major granule-associated species is a 15-kDa protein that is thought to be derived from the carboxyl terminus of the 40-kDa product by proteolytic processing. Alternative splicing resulting in different isoforms of this gene product has been described in the literature. [provided by RefSeq, Jul 2008].

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Catégories TIA1 en vedette

TIA1 Anticorps

High quality antibodies with extensive validation data.

TIA1 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

TIA1 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC, ELISA, FACS, ICC
Validations
  • (6)
N° du produit ABIN7193566
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC, IHC (p)
Validations
  • (8)
N° du produit ABIN1501387
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Application WB, IHC, IF
Validations
  • (5)
N° du produit ABIN7262058
Quantité 200 μL
Fiche technique Fiche technique

TIA1 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN6231628
Quantité 96 tests
Fiche technique Fiche technique

TIA1 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN7125397
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1322742
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
N° du produit ABIN3073943
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits TIA1

Hu, Wang, Tang, Yang, Qin, Chen: "Inclusion bodies of human parainfluenza virus type 3 inhibit antiviral stress granule formation by shielding viral RNAs." dans: PLoS pathogens, Vol. 14, Issue 3, pp. e1006948, (2018) (PubMed).

Hackman, Sarparanta, Lehtinen, Vihola, Evilä, Jonson, Luque, Kere, Screen, Chinnery, Åhlberg, Edström, Udd: "Welander distal myopathy is caused by a mutation in the RNA-binding protein TIA1." dans: Annals of neurology, Vol. 73, Issue 4, pp. 500-9, (2014) (PubMed).

Klar, Sobol, Melberg, Mäbert, Ameur, Johansson, Feuk, Entesarian, Orlén, Casar-Borota, Dahl: "Welander distal myopathy caused by an ancient founder mutation in TIA1 associated with perturbed splicing." dans: Human mutation, Vol. 34, Issue 4, pp. 572-7, (2013) (PubMed).

Yang, Peng, Murray, Otsuka, Kedersha, Schoenberg: "Polysome-bound endonuclease PMR1 is targeted to stress granules via stress-specific binding to TIA-1." dans: Molecular and cellular biology, Vol. 26, Issue 23, pp. 8803-13, (2006) (PubMed).

Synonymes et noms alternatifs relatifs à TIA1

nucleolysin TIA-1 isoform p40 (PTRG_10065), hypothetical protein (PGTG_08590), nucleolysin TIAR (LOC5568274), nucleolysin tia-1 (CpipJ_CPIJ013665), nucleolysin TIA-1 (VDBG_07004), nucleolysin TIA-1 (MGYG_03339), nucleolysin TIA-1 (Tsp_15456), cytotoxic granule-associated RNA binding protein 1 (tia1), cytotoxic granule-associated RNA binding protein 1 (Tia1), TIA1 cytotoxic granule associated RNA binding protein (TIA1), TIA1 cytotoxic granule-associated RNA binding protein (Tia1), TIA1 cytotoxic granule-associated RNA binding protein L homeolog (tia1.L), 2310050N03Rik, AI256674, mTIA-1, TIA-1, tia-1, tia1, TIAL1, TIAR, WDM

Protein level used designations for TIA1

  • nucleolysin TIA-1 isoform p40
  • nucleolysin tia-1
  • nucleolysin TIA-1
  • TIA1 cytotoxic granule-associated RNA binding protein
  • Nucleolysin TIA-1
  • RNA-binding protein TIA-1
  • T-cell-restricted intracellular antigen-1
  • cytotoxic granule-associated RNA-binding protein 1
  • p40-TIA-1 (containing p15-TIA-1)
  • TIA1 cytotoxic granule-associated RNA binding protein-like 1
  • nucleolysin TIAR
  • cytotoxic granule-associated RNA binding protein 1
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