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TIE1 Produits

(tyrosine Kinase with Immunoglobulin-Like and EGF-Like Domains 1 (TIE1))
This gene encodes a member of the tyrosine protein kinase family. The encoded protein plays a critical role in angiogenesis and blood vessel stability by inhibiting angiopoietin 1 signaling through the endothelial receptor tyrosine kinase Tie2. Ectodomain cleavage of the encoded protein relieves inhibition of Tie2 and is mediated by multiple factors including vascular endothelial growth factor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011].

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Catégories TIE1 en vedette

TIE1 Anticorps

High quality antibodies with extensive validation data.

TIE1 Kits ELISA

Reliable ELISA kits for a wide range of species.

TIE1 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

TIE1 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (6)
N° du produit ABIN2683015
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IHC (p), ICC, IHC (fro)
Validations
  • (4)
N° du produit ABIN7442504
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IHC (p), ICC, IHC (fro)
Validations
  • (3)
N° du produit ABIN7431122
Quantité 100 μL
Fiche technique Fiche technique

TIE1 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (6)
N° du produit ABIN6730883
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6960330
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Zebrafish (Danio rerio)
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN1572722
Quantité 96 tests
Fiche technique Fiche technique

TIE1 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Insect Cells
Validations
N° du produit ABIN1589962
Quantité 20 μg
Fiche technique Fiche technique
Reactivity Mouse
Source Insect Cells
Validations
N° du produit ABIN1589958
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Mouse
Source CHO Cells
Validations
N° du produit ABIN1589960
Quantité 20 μg
Fiche technique Fiche technique

Dernières publications sur nos produits TIE1

Leppänen, Saharinen, Alitalo: "Structural basis of Tie2 activation and Tie2/Tie1 heterodimerization." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 114, Issue 17, pp. 4376-4381, (2017) (PubMed).

Morooka, Futaki, Sato-Nishiuchi, Nishino, Totani, Shimono, Nakano, Nakajima, Mochizuki, Sekiguchi: "Polydom Is an Extracellular Matrix Protein Involved in Lymphatic Vessel Remodeling." dans: Circulation research, Vol. 120, Issue 8, pp. 1276-1288, (2017) (PubMed).

Hakanpaa, Sipila, Leppanen, Gautam, Nurmi, Jacquemet, Eklund, Ivaska, Alitalo, Saharinen: "Endothelial destabilization by angiopoietin-2 via integrin β1 activation." dans: Nature communications, Vol. 6, pp. 5962, (2015) (PubMed).

Saulle, Guerriero, Petronelli, Coppotelli, Gabbianelli, Morsilli, Spinello, Pelosi, Castelli, Testa, Coppola: "Autocrine role of angiopoietins during megakaryocytic differentiation." dans: PLoS ONE, Vol. 7, Issue 7, pp. e39796, (2012) (PubMed).

Marron, Singh, Tahir, Kavumkal, Kim, Koh, Brindle: "Regulated proteolytic processing of Tie1 modulates ligand responsiveness of the receptor-tyrosine kinase Tie2." dans: The Journal of biological chemistry, Vol. 282, Issue 42, pp. 30509-17, (2007) (PubMed).

Kim, Shin, Kim, Choi, Byun, Jeon, Suh, Kim: "Interaction between Tie receptors modulates angiogenic activity of angiopoietin2 in endothelial progenitor cells." dans: Cardiovascular research, Vol. 72, Issue 3, pp. 394-402, (2006) (PubMed).

Lin, Lee, Sun: "Functions of the activation loop in Csk protein-tyrosine kinase." dans: The Journal of biological chemistry, Vol. 278, Issue 26, pp. 24072-7, (2003) (PubMed).

Huang, Chen, Inoue, Chen: "Tyrosine phosphorylation of I-kappa B kinase alpha/beta by protein kinase C-dependent c-Src activation is involved in TNF-alpha-induced cyclooxygenase-2 expression." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 170, Issue 9, pp. 4767-75, (2003) (PubMed).

Natarajan, Rajala, Chodosh: "Corneal IL-8 expression following adenovirus infection is mediated by c-Src activation in human corneal fibroblasts." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 170, Issue 12, pp. 6234-43, (2003) (PubMed).

Danet, Pan, Luongo, Bonnet, Simon: "Expansion of human SCID-repopulating cells under hypoxic conditions." dans: The Journal of clinical investigation, Vol. 112, Issue 1, pp. 126-35, (2003) (PubMed).

Synonymes et noms alternatifs relatifs à TIE1

tyrosine kinase with immunoglobulin like and EGF like domains 1 (TIE1), tyrosine kinase with immunoglobulin-like and EGF-like domains 1 (Tie1), tyrosine-protein kinase receptor Tie-1 (CpipJ_CPIJ018933), endothelium-specific receptor tyrosine kinase 1 (tie1), D430008P04Rik, JTK14, TIE, tie-1

Protein level used designations for TIE1

  • tyrosine kinase with immunoglobulin and epidermal growth factor homology domains 1
  • tyrosine-protein kinase receptor Tie-1
  • tyrosine kinase receptor 1
  • tyrosine kinase with immunoglobulin and epidermal growth factor homology domains
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