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TIGIT Produits

(T Cell Immunoreceptor with Ig and ITIM Domains (TIGIT))

Catégories

This gene encodes a member of the PVR (poliovirus receptor) family of immunoglobin proteins. The product of this gene is expressed on several classes of T cells including follicular B helper T cells (TFH). The protein has been shown to bind PVR with high affinity\; this binding is thought to assist interactions between TFH and dendritic cells to regulate T cell dependent B cell responses.[provided by RefSeq, Sep 2009].

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Catégories TIGIT en vedette

TIGIT Anticorps

High quality antibodies with extensive validation data.

TIGIT Kits ELISA

Reliable ELISA kits for a wide range of species.

TIGIT Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

TIGIT recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC, ICC, IP
Validations
  • (5)
N° du produit ABIN7439486
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application ELISA, FACS
Validations
  • (4)
N° du produit ABIN7193227
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application ELISA, IHC, FACS, Coat, StM
Validations
  • (4)
N° du produit ABIN6939305
Quantité 100 μg
Fiche technique Fiche technique

TIGIT recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6959836
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN6730832
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN4884793
Quantité 96 tests
Fiche technique Fiche technique

TIGIT recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (6)
N° du produit ABIN7275729
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (6)
N° du produit ABIN7275728
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (4)
N° du produit ABIN7275730
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits TIGIT

Bai, Gao, Hu, Liu, Li, Dong, Huang, Zhu, Zhou, Li, Shao: "Self-Assembled Multivalent Aptamer Nanoparticles with Potential CAR-like Characteristics Could Activate T Cells and Inhibit Melanoma Growth." dans: Molecular therapy oncolytics, Vol. 17, pp. 9-20, (2020) (PubMed).

Brockmann, Soukou, Steglich, Czarnewski, Zhao, Wende, Bedke, Ergen, Manthey, Agalioti, Geffken, Seiz, Parigi, Sorini, Geginat, Fujio, Jacobs, Roesch, Izbicki, Lohse, Flavell, Krebs, Gustafsson et al.: "Molecular and functional heterogeneity of IL-10-producing CD4+ T cells. ..." dans: Nature communications, Vol. 9, Issue 1, pp. 5457, (2019) (PubMed).

Nuñez, Ziblat, Secchiari, Torres, Sierra, Raffo Iraolagoitia, Araya, Domaica, Fuertes, Zwirner: "Human M2 Macrophages Limit NK Cell Effector Functions through Secretion of TGF-β and Engagement of CD85j." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 200, Issue 3, pp. 1008-1015, (2018) (PubMed).

Downs-Canner, Berkey, Delgoffe, Edwards, Curiel, Odunsi, Bartlett, Obermajer: "Suppressive IL-17A+Foxp3+and ex-Th17 IL-17AnegFoxp3+Tregcells are a source of tumour-associated Tregcells." dans: Nature communications, Vol. 8, pp. 14649, (2017) (PubMed).

Yasuma, Yasunaga, Takemoto, Sugata, Mitobe, Takenouchi, Nakagawa, Suzuki, Matsuoka: "HTLV-1 bZIP Factor Impairs Anti-viral Immunity by Inducing Co-inhibitory Molecule, T Cell Immunoglobulin and ITIM Domain (TIGIT)." dans: PLoS pathogens, Vol. 12, Issue 1, pp. e1005372, (2016) (PubMed).

Gur, Ibrahim, Isaacson, Yamin, Abed, Gamliel, Enk, Bar-On, Stanietsky-Kaynan, Coppenhagen-Glazer, Shussman, Almogy, Cuapio, Hofer, Mevorach, Tabib, Ortenberg, Markel, Miklić, Jonjic, Brennan, Garrett et al.: "Binding of the Fap2 protein of Fusobacterium nucleatum to human inhibitory receptor TIGIT protects tumors from immune cell attack. ..." dans: Immunity, Vol. 42, Issue 2, pp. 344-55, (2015) (PubMed).

Zhang, Wang, Zhou, Liang, Bai, Yang, Gu, Gao, Dong, Zhu, Chen: "Increased expression of TIGIT on CD4+ T cells ameliorates immune-mediated bone marrow failure of aplastic anemia." dans: Journal of cellular biochemistry, Vol. 115, Issue 11, pp. 1918-27, (2014) (PubMed).

Stanietsky, Rovis, Glasner, Seidel, Tsukerman, Yamin, Enk, Jonjic, Mandelboim: "Mouse TIGIT inhibits NK-cell cytotoxicity upon interaction with PVR." dans: European journal of immunology, Vol. 43, Issue 8, pp. 2138-50, (2013) (PubMed).

Synonymes et noms alternatifs relatifs à TIGIT

T-cell immunoreceptor with Ig and ITIM domains (TIGIT), T cell immunoreceptor with Ig and ITIM domains (Tigit), ENSMUSG00000071552, RGD1563191, VSIG9, VSTM3, Vstm3, WUCAM

Protein level used designations for TIGIT

  • T-cell immunoreceptor with Ig and ITIM domains
  • V-set and immunoglobulin domain containing 9
  • V-set and immunoglobulin domain-containing protein 9
  • V-set and transmembrane domain containing 3
  • V-set and transmembrane domain-containing protein 3
  • Washington University cell adhesion molecule
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