TIRAP Produits
(Toll-Interleukin 1 Receptor (TIR) Domain Containing Adaptor Protein (TIRAP))
Catégories
The innate immune system recognizes microbial pathogens through Toll-like receptors (TLRs), which identify pathogen-associated molecular patterns. Different TLRs recognize different pathogen-associated molecular patterns and all TLRs have a Toll-interleukin 1 receptor (TIR) domain, which is responsible for signal transduction. The protein encoded by this gene is a TIR adaptor protein involved in the TLR4 signaling pathway of the immune system. It activates NF-kappa-B, MAPK1, MAPK3 and JNK, which then results in cytokine secretion and the inflammatory response. Alternative splicing of this gene results in several transcript variants\; however, not all variants have been fully described. [provided by RefSeq, Jul 2008].
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Catégories TIRAP en vedette
TIRAP Anticorps
High quality antibodies with extensive validation data.
TIRAP Kits ELISA
Reliable ELISA kits for a wide range of species.
TIRAP Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
TIRAP recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC (p), IHC (fro), ICC
Validations
- (8)
N° du produit
ABIN7441712
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IF
Validations
- (1)
- (5)
N° du produit
ABIN6149192
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (3)
N° du produit
ABIN7172290
Quantité
100 μL
Fiche technique
Fiche technique
TIRAP recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6970732
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6960023
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN6223712
Quantité
96 tests
Fiche technique
Fiche technique
TIRAP recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1322812
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7409917
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN2132191
Quantité
50 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits TIRAP
: "Proximity Ligation Assays for In Situ Detection of Innate Immune Activation: Focus on In Vitro-Transcribed mRNA." dans: Molecular therapy. Nucleic acids, Vol. 14, pp. 52-66, (2019) (PubMed).: "Toll-Like Receptor 4 Mediates Methamphetamine-Induced Neuroinflammation through Caspase-11 Signaling Pathway in Astrocytes." dans: Frontiers in molecular neuroscience, Vol. 10, pp. 409, (2017) (PubMed).
: "Heterodimer-specific TLR2 stimulation results in divergent functional outcomes in B-cell precursor acute lymphoblastic leukemia." dans: European journal of immunology, Vol. 45, Issue 7, pp. 1980-90, (2015) (PubMed).
: "Chemoprevention Activity of Dipyridamole in the MMTV-PyMT Transgenic Mouse Model of Breast Cancer." dans: Cancer prevention research (Philadelphia, Pa.), Vol. 6, Issue 5, pp. 437-47, (2013) (PubMed).
: "Phosphatidylinositol 4-phosphate 5-kinase ? facilitates Toll-like receptor 4-mediated microglial inflammation through regulation of the Toll/interleukin-1 receptor domain-containing adaptor protein ..." dans: The Journal of biological chemistry, Vol. 288, Issue 8, pp. 5645-59, (2013) (PubMed).
: "Preferential expression and function of Toll-like receptor 3 in human astrocytes." dans: Journal of neuroimmunology, Vol. 159, Issue 1-2, pp. 12-9, (2005) (PubMed).
: "Advantages and disadvantages of cytidine deamination." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 172, Issue 11, pp. 6513-8, (2004) (PubMed).
: "Distinct pathways of LPS-induced NF-kappa B activation and cytokine production in human myeloid and nonmyeloid cells defined by selective utilization of MyD88 and Mal/TIRAP." dans: Blood, Vol. 103, Issue 6, pp. 2229-37, (2004) (PubMed).
: "TLRs: differential adapter utilization by toll-like receptors mediates TLR-specific patterns of gene expression." dans: Molecular interventions, Vol. 3, Issue 8, pp. 466-77, (2004) (PubMed).
: "The expanding family of MyD88-like adaptors in Toll-like receptor signal transduction." dans: Molecular immunology, Vol. 41, Issue 6-7, pp. 577-82, (2004) (PubMed).
Synonymes et noms alternatifs relatifs à TIRAP
toll-interleukin 1 receptor (TIR) domain containing adaptor protein (tirap), TIR domain containing adaptor protein (TIRAP), toll-interleukin 1 receptor (TIR) domain containing adaptor protein L homeolog (tirap.L), TIR domain containing adaptor protein (Tirap), toll-interleukin 1 receptor (TIR) domain-containing adaptor protein (Tirap), AA407980, BACTS1, C130027E04Rik, mal, Mal, MyD88-2, Tlr4ap, wyatt, WyattProtein level used designations for TIRAP
- MyD88 adapter-like protein
- Toll-interleukin 1 receptor domain-containing adaptor protein
- toll/interleukin-1 receptor domain-containing adapter protein
- TIR domain-containing adaptor protein
- Toll-like receptor adaptor protein
- adapter protein wyatt
- adaptor protein Wyatt
- toll-interleukin 1 receptor domain-containing adaptor protein
- TIR domain-containing adapter protein
- Toll-like receptor 4 adaptor protein
- myD88 adapter-like protein
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