TLR3 Produits
(Toll-Like Receptor 3 (TLR3))
Catégories
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor is most abundantly expressed in placenta and pancreas, and is restricted to the dendritic subpopulation of the leukocytes. It recognizes dsRNA associated with viral infection, and induces the activation of NF-kappaB and the production of type I interferons. It may thus play a role in host defense against viruses. Use of alternative polyadenylation sites to generate different length transcripts has been noted for this gene. [provided by RefSeq, Jul 2008].
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Catégories TLR3 en vedette
TLR3 Anticorps
High quality antibodies with extensive validation data.
TLR3 Kits ELISA
Reliable ELISA kits for a wide range of species.
TLR3 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
TLR3 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (7)
N° du produit
ABIN7434491
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC, IF
Validations
- (7)
N° du produit
ABIN6149219
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro)
Validations
- (4)
- (4)
N° du produit
ABIN686617
Quantité
100 μL
Fiche technique
Fiche technique
TLR3 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (6)
N° du produit
ABIN6720574
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (3)
- (1)
N° du produit
ABIN6960031
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6970740
Quantité
96 tests
Fiche technique
Fiche technique
TLR3 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
HEK-293 Cells
Validations
- (4)
N° du produit
ABIN7275746
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Cynomolgus
Source
HEK-293 Cells
Validations
- (2)
N° du produit
ABIN7275745
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
HEK-293 Cells
Validations
- (2)
N° du produit
ABIN7275748
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits TLR3
: "Bronchial mucosal IFN-α/β and pattern recognition receptor expression in patients with experimental rhinovirus-induced asthma exacerbations." dans: The Journal of allergy and clinical immunology, Vol. 143, Issue 1, pp. 114-125.e4, (2019) (PubMed).: "Vinpocetine regulates levels of circulating TLRs in Parkinson's disease patients." dans: Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, Vol. 40, Issue 1, pp. 113-120, (2019) (PubMed).
: "Toll-like receptor 3 controls QT interval on the electrocardiogram by targeting the degradation of Kv4.2/4.3 channels in the endoplasmic reticulum." dans: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 33, Issue 5, pp. 6197-6208, (2019) (PubMed).
: "Loss of TLR3 and its downstream signaling accelerates acinar cell damage in the acute phase of pancreatitis." dans: Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.], Vol. 19, Issue 1, pp. 149-157, (2019) (PubMed).
: "Anti-tumour activity of oncolytic reovirus against canine histiocytic sarcoma cells." dans: Veterinary and comparative oncology, Vol. 17, Issue 2, pp. 184-193, (2019) (PubMed).
: "Activation of Toll-like receptor 3 promotes pathological corneal neovascularization by enhancement of SDF-1-mediated endothelial progenitor cell recruitment." dans: Experimental eye research, Vol. 178, pp. 177-185, (2019) (PubMed).
: "Calcium/Calmodulin-Dependent Protein Kinase IV Mediates IFN-γ-Induced Immune Behaviors in Skeletal Muscle Cells." dans: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, Vol. 46, Issue 1, pp. 351-364, (2018) (PubMed).
: "Daily oscillations in expression and responsiveness of Toll-like receptors in splenic immune cells." dans: Heliyon, Vol. 4, Issue 3, pp. e00579, (2018) (PubMed).
: "Substance P represents a novel first-line defense mechanism in the nose." dans: The Journal of allergy and clinical immunology, (2017) (PubMed).
: "Central role of the TIR-domain-containing adaptor-inducing interferon-β (TRIF) adaptor protein in murine sterile liver injury." dans: Hepatology (Baltimore, Md.), Vol. 65, Issue 4, pp. 1336-1351, (2017) (PubMed).
Synonymes et noms alternatifs relatifs à TLR3
toll like receptor 3 (TLR3), toll-like receptor 3 (Tlr3), toll like receptor 3 (Tlr3), toll-like receptor 3 (tlr3), AI957183, CD283, IIAE2, zgc:123006Protein level used designations for TLR3
- toll-like receptor 3
- toll-like receptor 3-like
- toll-like receptor 3 variant 1
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