TLR8 Produits
(Toll-Like Receptor 8 (TLR8))
Catégories
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is predominantly expressed in lung and peripheral blood leukocytes, and lies in close proximity to another family member, TLR7, on chromosome X. [provided by RefSeq, Jul 2008].
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Catégories TLR8 en vedette
TLR8 Anticorps
High quality antibodies with extensive validation data.
TLR8 Kits ELISA
Reliable ELISA kits for a wide range of species.
TLR8 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
TLR8 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IHC, IF
Validations
- (8)
N° du produit
ABIN3022015
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA
Validations
- (1)
- (3)
N° du produit
ABIN526632
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Application
WB, IHC, ELISA, ICC, IF
Validations
- (4)
N° du produit
ABIN6265604
Quantité
100 μL
Fiche technique
Fiche technique
TLR8 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
N° du produit
ABIN6960040
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6970748
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Dog
Analytical Method
Quantitative
Validations
N° du produit
ABIN1059329
Quantité
96 tests
Fiche technique
Fiche technique
TLR8 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1322888
Quantité
25 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
N° du produit
ABIN5569497
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7395563
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits TLR8
: "Impaired expression and function of TLR8 in chronic HBV infection and its association with treatment responses during peg-IFN-α-2a antiviral therapy." dans: Clinics and research in hepatology and gastroenterology, (2017) (PubMed).: "The Expression of Toll-like Receptors in Normal Human and Murine Gastrointestinal Organs and the Effect of Microbiome and Cancer." dans: The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, Vol. 64, Issue 8, pp. 470-82, (2017) (PubMed).
: "FcγRIIIa Signaling Modulates Endosomal TLR Responses in Human CD4+T Cells." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 198, Issue 12, pp. 4596-4606, (2017) (PubMed).
: "Pellino-1 confers chemoresistance in lung cancer cells by upregulating cIAP2 through Lys63-mediated polyubiquitination." dans: Oncotarget, Vol. 7, Issue 27, pp. 41811-41824, (2016) (PubMed).
: "Localization of nucleic acid-sensing toll-like receptors in human and mouse pancreas." dans: APMIS : acta pathologica, microbiologica, et immunologica Scandinavica, Vol. 125, Issue 2, pp. 85-92, (2016) (PubMed).
: "Direct Toll-Like Receptor 8 signaling increases the functional avidity of human CD8+ T lymphocytes generated for adoptive T cell therapy strategies." dans: Immunity, inflammation and disease, Vol. 3, Issue 1, pp. 1-13, (2015) (PubMed).
: "TLR8 Senses Staphylococcus aureus RNA in Human Primary Monocytes and Macrophages and Induces IFN-β Production via a TAK1-IKKβ-IRF5 Signaling Pathway." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 195, Issue 3, pp. 1100-11, (2015) (PubMed).
: "Chromatin remodelling and autocrine TNFα are required for optimal interleukin-6 expression in activated human neutrophils." dans: Nature communications, Vol. 6, pp. 6061, (2015) (PubMed).
: "Toll-like receptor 3 expression and function in childhood idiopathic nephrotic syndrome." dans: Clinical and experimental immunology, Vol. 182, Issue 3, pp. 332-45, (2015) (PubMed).
: "Functional polymorphisms of TLR8 are associated with hepatitis C virus infection." dans: Immunology, Vol. 141, Issue 4, pp. 540-8, (2014) (PubMed).
Synonymes et noms alternatifs relatifs à TLR8
toll like receptor 8 (TLR8), toll-like receptor 8 (Tlr8), toll like receptor 8 (Tlr8), toll-like receptor 8 (TLR8), CD288
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