TMED10 Produits
(Transmembrane Emp24-Like Trafficking Protein 10 (TMED10))
Catégories
This gene is a member of the EMP24/GP25L/p24 family and encodes a protein with a GOLD domain. This type I membrane protein is localized to the plasma membrane and golgi cisternae and is involved in vesicular protein trafficking. The protein is also a member of a heteromeric secretase complex and regulates the complex's gamma-secretase activity without affecting its epsilon-secretase activity. Mutations in this gene have been associated with early-onset familial Alzheimer's disease. This gene has a pseudogene on chromosome 8. [provided by RefSeq, Jul 2008].
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Catégories TMED10 en vedette
TMED10 Anticorps
High quality antibodies with extensive validation data.
TMED10 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
TMED10 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human, Mouse
Application
WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro), ICC
Validations
- (2)
N° du produit
ABIN1386483
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
ELISA, IF, FACS
Validations
- (2)
N° du produit
ABIN190858
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB
Validations
- (1)
N° du produit
ABIN1536747
Quantité
400 μL
Fiche technique
Fiche technique
TMED10 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN6387259
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN2132195
Quantité
20 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits TMED10
: "TMP21 is a presenilin complex component that modulates gamma-secretase but not epsilon-secretase activity." dans: Nature, Vol. 440, Issue 7088, pp. 1208-12, (2006) (PubMed).: "Functional reconstitution of gamma-secretase through coordinated expression of presenilin, nicastrin, Aph-1, and Pen-2." dans: Journal of neuroscience research, Vol. 77, Issue 3, pp. 309-22, (2004) (PubMed).
: "The cell biology of beta-amyloid precursor protein and presenilin in Alzheimer's disease." dans: Trends in cell biology, Vol. 8, Issue 11, pp. 447-53, (1999) (PubMed).
Synonymes et noms alternatifs relatifs à TMED10
transmembrane p24 trafficking protein 10 L homeolog (tmed10.L), transmembrane p24 trafficking protein 10 (TMED10), transmembrane p24 trafficking protein 10 (Tmed10), transmembrane p24 trafficking protein 10 (tmed10), 1110014C03Rik, fe06g04, p23, P24(DELTA), p24delta1, S31I125, S31III125, Tmp-21-I, tmp21, TMP21, Tmp21, wu:fb98e10, wu:fe06g04, zgc:85681Protein level used designations for TMED10
- transmembrane protein tmp21
- 21 kDa transmembrane trafficking protein
- 21 kDa transmembrane-trafficking protein
- p24 family protein delta-1
- p24delta
- p24delta1
- transmembrane emp24 domain-containing protein 10
- transmembrane protein Tmp21
- transmembrane trafficking protein
- integral membrane protein Tmp21-I (p23)
- transmembrane trafficking protein 21
- p24 delta 1
- integral membrane protein p23
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