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TNFRSF10B Produits

(Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B))

Catégories

The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene. [provided by RefSeq, Mar 2009].

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Catégories TNFRSF10B en vedette

TNFRSF10B Anticorps

High quality antibodies with extensive validation data.

TNFRSF10B Kits ELISA

Reliable ELISA kits for a wide range of species.

TNFRSF10B Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

TNFRSF10B recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (7)
N° du produit ABIN7442663
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC, IF
Validations
  • (4)
N° du produit ABIN7271062
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Application WB, IHC (p)
Validations
  • (1)
  • (4)
N° du produit ABIN5518794
Quantité 100 μg
Fiche technique Fiche technique

TNFRSF10B recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6970967
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6960278
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6960279
Quantité 96 tests
Fiche technique Fiche technique

TNFRSF10B recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (4)
N° du produit ABIN7275780
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Mouse
Source HEK-293 Cells
Validations
  • (3)
N° du produit ABIN7275784
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (3)
N° du produit ABIN7275779
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits TNFRSF10B

Fang, Lu, Wang, Wu, Mei, Zheng, Xu, Lenahan, Chen, Zhang, Hong: "HIF-1α Mediates TRAIL-Induced Neuronal Apoptosis via Regulating DcR1 Expression Following Traumatic Brain Injury." dans: Frontiers in cellular neuroscience, Vol. 14, pp. 192, (2020) (PubMed).

Yang, Park, Kim, Lee, Lee, Jang: "LY3009120, a pan-Raf kinase inhibitor, inhibits adipogenesis of 3T3-L1 cells by controlling the expression and phosphorylation of C/EBP-α, PPAR-γ, STAT‑3, FAS, ACC, perilipin A, and AMPK." dans: International journal of molecular medicine, Vol. 42, Issue 6, pp. 3477-3484, (2019) (PubMed).

Luo, Pan, Liu, Yuan, Yan: "Sphingomyelin synthase 2 overexpression promotes cisplatin-induced apoptosis of HepG2 cells." dans: Oncology letters, Vol. 15, Issue 1, pp. 483-488, (2018) (PubMed).

Park, Park, Ramalingam, Yadav, Cho, Hong, More, Bae, Bishop-Bailey, Kano, Noguchi, Jang, Lee, Lee, Choi, Jang: "Meridianin C inhibits the growth of YD-10B human tongue cancer cells through macropinocytosis and the down-regulation of Dickkopf-related protein-3." dans: Journal of cellular and molecular medicine, Vol. 22, Issue 12, pp. 5833-5846, (2018) (PubMed).

Mettler Izquierdo, Varela, Park, Collarini, Lu, Pramanick, Rucker, Lopalco, Etches, Harriman: "High-efficiency antibody discovery achieved with multiplexed microscopy." dans: Microscopy (Oxford, England), Vol. 65, Issue 4, pp. 341-52, (2018) (PubMed).

Hutt, Fellermeier-Kopf, Seifert, Schmitt, Pfizenmaier, Kontermann: "Targeting scFv-Fc-scTRAIL fusion proteins to tumor cells." dans: Oncotarget, Vol. 9, Issue 13, pp. 11322-11335, (2018) (PubMed).

Shlyakhtina, Pavet, Gronemeyer: "Dual role of DR5 in death and survival signaling leads to TRAIL resistance in cancer cells." dans: Cell death & disease, Vol. 8, Issue 8, pp. e3025, (2018) (PubMed).

Lee, Hyun, Kim, Kang, Kim: "Potential Role of CD133 Expression in the Susceptibility of Human Liver Cancer Stem-Like Cells to TRAIL." dans: Oncology research, Vol. 24, Issue 6, pp. 495-509, (2017) (PubMed).

Hartwig, Montinaro, von Karstedt, Sevko, Surinova, Chakravarthy, Taraborrelli, Draber, Lafont, Arce Vargas, El-Bahrawy, Quezada, Walczak: "The TRAIL-Induced Cancer Secretome Promotes a Tumor-Supportive Immune Microenvironment via CCR2." dans: Molecular cell, Vol. 65, Issue 4, pp. 730-742.e5, (2017) (PubMed).

Rivoltini, Chiodoni, Squarcina, Tortoreto, Villa, Vergani, Bürdek, Botti, Arioli, Cova, Mauri, Vergani, Bianchi, Della Mina, Cantone, Bollati, Zaffaroni, Gianni, Colombo, Huber: "TNF-Related Apoptosis-Inducing Ligand (TRAIL)-Armed Exosomes Deliver Proapoptotic Signals to Tumor Site." dans: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 22, Issue 14, pp. 3499-512, (2016) (PubMed).

Synonymes et noms alternatifs relatifs à TNFRSF10B

tumor necrosis factor receptor superfamily, member 10b (Tnfrsf10b), tumor necrosis factor receptor superfamily, member 10b (TNFRSF10B), tumor necrosis factor receptor superfamily member 10b S homeolog (tnfrsf10b.S), tumor necrosis factor receptor superfamily member 10b L homeolog (tnfrsf10b.L), tumor necrosis factor receptor superfamily member 10b (tnfrsf10b), TNF receptor superfamily member 10b (TNFRSF10B), cd262, CD262, dr5, DR5, killer, KILLER, KILLER/DR5, Ly98, MK, TNFRSF10B, TRAIL-R2, trailr2, TRAILR2, trick2, TRICK2, trick2a, TRICK2A, trick2b, TRICK2B, trickb, TRICKB, xDR-M1, xDR-M2, ztnfr9, ZTNFR9

Protein level used designations for TNFRSF10B

  • tumor necrosis factor receptor superfamily, member 10b
  • death receptor-M2
  • death receptor-M1
  • Fas-like protein
  • TNF-related apoptosis-inducing ligand receptor 2
  • apoptosis inducing protein TRICK2A/2B
  • apoptosis inducing receptor TRAIL-R2
  • cytotoxic TRAIL receptor-2
  • death domain containing receptor for TRAIL/Apo-2L
  • death receptor 5
  • p53-regulated DNA damage-inducible cell death receptor(killer)
  • tumor necrosis factor receptor superfamily member 10B
  • tumor necrosis factor receptor-like protein ZTNFR9
  • KILLER/DR5 TRAIL death-inducing receptor
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