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TNFSF15 Produits

(Tumor Necrosis Factor (Ligand) Superfamily, Member 15 (TNFSF15))

Catégories

The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is abundantly expressed in endothelial cells, but is not expressed in either B or T cells. The expression of this protein is inducible by TNF and IL-1 alpha. This cytokine is a ligand for receptor TNFRSF25 and decoy receptor TNFRSF21/DR6. It can activate NF-kappaB and MAP kinases, and acts as an autocrine factor to induce apoptosis in endothelial cells. This cytokine is also found to inhibit endothelial cell proliferation, and thus may function as an angiogenesis inhibitor. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2011].

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Catégories TNFSF15 en vedette

TNFSF15 Anticorps

High quality antibodies with extensive validation data.

TNFSF15 Kits ELISA

Reliable ELISA kits for a wide range of species.

TNFSF15 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

TNFSF15 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Mouse
Application WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro)
Validations
  • (1)
  • (4)
N° du produit ABIN709556
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application IHC, StM
Validations
  • (5)
N° du produit ABIN6941291
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application IHC, StM
Validations
  • (4)
N° du produit ABIN6941290
Quantité 100 μg
Fiche technique Fiche technique

TNFSF15 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6970946
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6960752
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6974123
Quantité 96 tests
Fiche technique Fiche technique

TNFSF15 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (3)
N° du produit ABIN7274680
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Mouse
Source HEK-293 Cells
Validations
  • (3)
N° du produit ABIN7274686
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Mouse
Source HEK-293 Cells
Validations
  • (2)
N° du produit ABIN7274685
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits TNFSF15

Pham, ODonnell, Al-Shamkhani, Kerrinnes, Tsolis, McSorley: "T cell expression of IL-18R and DR3 is essential for non-cognate stimulation of Th1 cells and optimal clearance of intracellular bacteria." dans: PLoS pathogens, Vol. 13, Issue 8, pp. e1006566, (2017) (PubMed).

?lebioda, Bojarska-Junak, Stanis?awowski, Cyman, Wierzbicki, Roli?ski, Celi?ski, Kmie?: "TL1A as a potential local inducer of IL17A Expression in colon mucosa of inflammatory bowel disease patients." dans: Scandinavian journal of immunology, (2015) (PubMed).

Qin, Xu, Qi, Yang, Zhang, Liu, Xu, Xiang, Xiao, Cao, Wei, Zhang, Li: "Tumour necrosis factor superfamily member 15 (Tnfsf15) facilitates lymphangiogenesis via up-regulation of Vegfr3 gene expression in lymphatic endothelial cells." dans: The Journal of pathology, Vol. 237, Issue 3, pp. 307-18, (2015) (PubMed).

Liu, Wang, Ming, Song, Zhang, Chen, Zeng, Mao: "S100A9: A Potential Biomarker for the Progression of Non-Alcoholic Fatty Liver Disease and the Diagnosis of Non-Alcoholic Steatohepatitis." dans: PLoS ONE, Vol. 10, Issue 5, pp. e0127352, (2015) (PubMed).

Khan, Tsai, Schreiber, Wolf, Deyev, Podack: "Cloning, expression, and functional characterization of TL1A-Ig." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 190, Issue 4, pp. 1540-50, (2013) (PubMed).

Wen, Zhuang, Luo, Wei: "TL1A-induced NF-kappaB activation and c-IAP2 production prevent DR3-mediated apoptosis in TF-1 cells." dans: The Journal of biological chemistry, Vol. 278, Issue 40, pp. 39251-8, (2003) (PubMed).

Bamias, Martin, Marini, Hoang, Mishina, Ross, Sachedina, Friel, Mize, Bickston, Pizarro, Wei, Cominelli: "Expression, localization, and functional activity of TL1A, a novel Th1-polarizing cytokine in inflammatory bowel disease." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 171, Issue 9, pp. 4868-74, (2003) (PubMed).

Puthalakath, Villunger, OReilly, Beaumont, Coultas, Cheney, Huang, Strasser: "Bmf: a proapoptotic BH3-only protein regulated by interaction with the myosin V actin motor complex, activated by anoikis." dans: Science (New York, N.Y.), Vol. 293, Issue 5536, pp. 1829-32, (2001) (PubMed).

Hunt, Evan: "Apoptosis. Till death us do part." dans: Science (New York, N.Y.), Vol. 293, Issue 5536, pp. 1784-5, (2001) (PubMed).

Bodmer, Burns, Schneider, Hofmann, Steiner, Thome, Bornand, Hahne, Schröter, Becker, Wilson, French, Browning, MacDonald, Tschopp: "TRAMP, a novel apoptosis-mediating receptor with sequence homology to tumor necrosis factor receptor 1 and Fas(Apo-1/CD95)." dans: Immunity, Vol. 6, Issue 1, pp. 79-88, (1997) (PubMed).

Synonymes et noms alternatifs relatifs à TNFSF15

tumor necrosis factor superfamily member 15 (TNFSF15), TNF superfamily member 15 (TNFSF15), tumor necrosis factor (ligand) superfamily, member 15 (Tnfsf15), TNF superfamily member 15 (Tnfsf15), TL1, Tl1, TL1A, Tl1a, TTPAL, VEGI, Vegi, VEGI192A

Protein level used designations for TNFSF15

  • tumor necrosis factor ligand superfamily member 15
  • vascular endothelial growth inhibitor
  • tocopherol (alpha) transfer protein-like
  • TNF ligand-related molecule 1
  • TNF superfamily ligand TL1A
  • vascular endothelial cell growth inhibitor
  • vascular endothelial growth inhibitor-192A
  • bM20K13.3 (tumor necrosis factor (ligand) superfamily, member 15)
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