TNK1 Produits
(Tyrosine Kinase, Non-Receptor, 1 (TNK1))
Catégories
The protein encoded by this gene belongs to the tyrosine protein kinase family. Tyrosine protein kinases are important regulators of intracellular signal transduction pathways, mediating cellular proliferation, survival, and development. This gene is highly expressed in fetal tissues and at lower levels in few adult tissues, thus may function in signaling pathways utilized broadly during fetal development, and more selectively in adult tissues. It plays a negative regulatory role in the Ras-Raf1-MAPK pathway, and knockout mice have been shown to develop spontaneous tumors, suggesting a role as a tumor suppressor gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011].
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Catégories TNK1 en vedette
TNK1 Anticorps
High quality antibodies with extensive validation data.
TNK1 Kits ELISA
Reliable ELISA kits for a wide range of species.
TNK1 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
TNK1 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IHC (p)
Validations
- (1)
- (2)
N° du produit
ABIN392113
Quantité
400 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (2)
N° du produit
ABIN7192841
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
ELISA
Validations
- (2)
- (1)
N° du produit
ABIN1724711
Quantité
100 μL
Fiche technique
Fiche technique
TNK1 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Semi-Quantitative Sandwich ELISA
Validations
N° du produit
ABIN4886327
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN5593936
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Validations
N° du produit
ABIN2870179
Quantité
96 tests
Fiche technique
Fiche technique
TNK1 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Cell-free protein synthesis (CFPS)
Validations
N° du produit
ABIN3074517
Quantité
250 μg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
Cell-free protein synthesis (CFPS)
Validations
N° du produit
ABIN3136967
Quantité
250 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits TNK1
: "High-throughput RNAi screening identifies a role for TNK1 in growth and survival of pancreatic cancer cells." dans: Molecular cancer research : MCR, Vol. 9, Issue 6, pp. 724-32, (2011) (PubMed).: "Thirty-eight-negative kinase 1 (TNK1) facilitates TNFalpha-induced apoptosis by blocking NF-kappaB activation." dans: Oncogene, Vol. 26, Issue 45, pp. 6536-45, (2007) (PubMed).
: "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). ..." dans: Genome research, Vol. 14, Issue 10B, pp. 2121-7, (2004) (PubMed).
: "Kos1, a nonreceptor tyrosine kinase that suppresses Ras signaling." dans: Oncogene, Vol. 22, Issue 23, pp. 3562-77, (2003) (PubMed).
: "Phosphoinositide 3-kinase signalling pathways." dans: Journal of cell science, Vol. 114, Issue Pt 8, pp. 1439-45, (2001) (PubMed).
: "Oncogenic kinase signalling." dans: Nature, Vol. 411, Issue 6835, pp. 355-65, (2001) (PubMed).
: "The RET proto-oncogene in human cancers." dans: Oncogene, Vol. 19, Issue 49, pp. 5590-7, (2000) (PubMed).
: "Characterization of the tyrosine kinase Tnk1 and its binding with phospholipase C-gamma1." dans: Biochemical and biophysical research communications, Vol. 273, Issue 1, pp. 294-301, (2000) (PubMed).
Synonymes et noms alternatifs relatifs à TNK1
tyrosine kinase non receptor 1 (TNK1), tyrosine kinase, non-receptor, 1 (Tnk1), tyrosine kinase non receptor 1 (Tnk1), Ack-like, Kos1, Tnk1a, Tnk1bProtein level used designations for TNK1
- kinase of embryonic stem cells
- non-receptor tyrosine kinase
- non-receptor tyrosine-protein kinase TNK1
- CD38 negative kinase 1
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