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TNNI1 Produits

(Slow Skeletal Troponin I (TNNI1))
Troponin proteins associate with tropomyosin and regulate the calcium sensitivity of the myofibril contractile apparatus of striated muscles. Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit\; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. The TnI-fast and TnI-slow genes are expressed in fast-twitch and slow-twitch skeletal muscle fibers, respectively, while the TnI-cardiac gene is expressed exclusively in cardiac muscle tissue. This gene encodes the Troponin-I-skeletal-slow-twitch protein. This gene is expressed in cardiac and skeletal muscle during early development but is restricted to slow-twitch skeletal muscle fibers in adults. The encoded protein prevents muscle contraction by inhibiting calcium-mediated conformational changes in actin-myosin complexes. [provided by RefSeq, Jul 2008].

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Catégories TNNI1 en vedette

TNNI1 Anticorps

High quality antibodies with extensive validation data.

TNNI1 Kits ELISA

Reliable ELISA kits for a wide range of species.

TNNI1 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

TNNI1 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Rat
Application WB, IHC, IP, ICC
Validations
  • (4)
N° du produit ABIN7435427
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Cow, Dog, Goat, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Application WB, IHC
Validations
  • (1)
  • (4)
N° du produit ABIN2777151
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (3)
N° du produit ABIN7435424
Quantité 100 μL
Fiche technique Fiche technique

TNNI1 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
N° du produit ABIN6960188
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6970874
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6962286
Quantité 96 tests
Fiche technique Fiche technique

TNNI1 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN7125117
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1323277
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7397315
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits TNNI1

Fan, Long, Yan, Wang, Shi, Bao, Hu, Li, Chen, Zheng, Yan: "Dietary leucine supplementation alters energy metabolism and induces slow-to-fast transitions in longissimus dorsi muscle of weanling piglets." dans: The British journal of nutrition, Vol. 117, Issue 9, pp. 1222-1234, (2017) (PubMed).

Park, Choi, Jung, Yu, Ryu, Kim, Jo, Choi, Jung: "Myogenic differentiation potential of human tonsil-derived mesenchymal stem cells and their potential for use to promote skeletal muscle regeneration." dans: International journal of molecular medicine, Vol. 37, Issue 5, pp. 1209-20, (2016) (PubMed).

Salzler, Shah, Doré, Bauerlein, Miloscio, Latres, Papadopoulos, Olson, MacDonald, Duan: "Myostatin deficiency but not anti-myostatin blockade induces marked proteomic changes in mouse skeletal muscle." dans: Proteomics, Vol. 16, Issue 14, pp. 2019-27, (2016) (PubMed).

Ma, Zheng, Hu, Wang, Yang, Jiang: "Dietary L-arginine supplementation affects the skeletal longissimus muscle proteome in finishing pigs." dans: PLoS ONE, Vol. 10, Issue 1, pp. e0117294, (2015) (PubMed).

Vyatchin, Shevchenko, Lazarev, Matusovsky, Sheludko: "Troponin-like regulation in muscle thin filaments of the mussel Crenomytilus grayanus (Bivalvia: Mytiloida)." dans: Biochimica et biophysica acta, Vol. 1854, Issue 10 Pt A, pp. 1444-50, (2015) (PubMed).

Stadler, Rexhepaj, Singan, Murphy, Pepperkok, Uhlén, Simpson, Lundberg: "Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells." dans: Nature methods, Vol. 10, Issue 4, pp. 315-23, (2013) (PubMed).

Chakraborty, Sengupta, Yutzey: "Tbx20 promotes cardiomyocyte proliferation and persistence of fetal characteristics in adult mouse hearts." dans: Journal of molecular and cellular cardiology, Vol. 62, pp. 203-13, (2013) (PubMed).

Harmelink, Peng, DeBenedittis, Chen, Shou, Jiao: "Myocardial Mycn is essential for mouse ventricular wall morphogenesis." dans: Developmental biology, Vol. 373, Issue 1, pp. 53-63, (2012) (PubMed).

Lichtenauer, Mildner, Hoetzenecker, Zimmermann, Podesser, Sipos, Berényi, Dworschak, Tschachler, Gyöngyösi, Ankersmit: "Secretome of apoptotic peripheral blood cells (APOSEC) confers cytoprotection to cardiomyocytes and inhibits tissue remodelling after acute myocardial infarction: a preclinical study." dans: Basic research in cardiology, Vol. 106, Issue 6, pp. 1283-97, (2011) (PubMed).

Engel, Kobayashi, Biesiadecki, Davis, Tikunova, Wu, Solaro: "Identification of a region of troponin I important in signaling cross-bridge-dependent activation of cardiac myofilaments." dans: The Journal of biological chemistry, Vol. 282, Issue 1, pp. 183-93, (2007) (PubMed).

Synonymes et noms alternatifs relatifs à TNNI1

troponin T1, slow skeletal type (TNNT1), troponin I1, slow skeletal type (TNNI1), troponin I, skeletal, slow 1 (Tnni1), troponin I1, slow skeletal type (Tnni1), troponin T1, skeletal, slow (Tnnt1), troponin T1, slow skeletal type (Tnnt1), troponin I1, slow skeletal type S homeolog (tnni1.S), troponin I type 1 (skeletal, slow) (TNNI1), troponin I4b, tandem duplicate 2 (tnni4b.2), 2700018B22Rik, AI747285, ANM, AW146156, Fang2, NEM5, SSTNI, ssTnI, ssTnT, STNT, sTnT, TnI-S4, TNN1, TNT, Tnt, TNTS, tnTs, troponin 1, zgc:86895

Protein level used designations for TNNI1

  • nemaline myopathy type 5
  • slow skeletal muscle troponin T
  • troponin T, slow skeletal muscle
  • troponin-T1, skeletal, slow
  • sTnT
  • tnTs
  • troponin T1, skeletal, slow
  • troponin T slow type isoform sTnT1
  • troponin I, slow skeletal muscle
  • troponin I, slow-twitch isoform
  • Troponin I, slow isoform
  • troponin I, skeletal, slow 1
  • skeletal muscle slow-twitch TnT
  • TnnI1
  • Troponin I, slow skeletal muscle
  • troponin I type 1 (skeletal, slow)
  • troponin I, skeletal, slow
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