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TNR1A Protein (AA 31-210) (GST tag)

TNR1A Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 90 % SDS
N° du produit ABIN5712514
  • Antigène
    TNR1A (Tumor Necrosis Factor Receptor Superfamily Member 1A (TNR1A))
    Type de proteíne
    Recombinant
    Attributs du protein
    AA 31-210
    Origine
    Humain
    Source
    Escherichia coli (E. coli)
    Purification/Conjugué
    Cette TNR1A protéine est marqué à la GST tag.
    Application
    SDS-PAGE (SDS)
    Séquence
    VPHLGDREKR DSVCPQGKYI HPQNNSICCT KCHKGTYLYN DCPGPGQDTD CRECESGSFT ASENHLRHCL SCSKCRKEMG QVEISSCTVD RDTVCGCRKN QYRHYWSENL FQCFNCSLCL NGTVHLSCQE KQNTVCTCHA GFFLRENECV SCSNCKKSLE CTKLCLPQIE NVKGTEDSGT
    Purification
    SDS-PAGE
    Pureté
    > 90 %
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.1-2 mg/mL
    Buffer
    20 mM Tris-HCl based buffer, pH 8.0
    Stock
    -80 °C,4 °C,-20 °C
    Stockage commentaire
    Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Antigène
    TNR1A (Tumor Necrosis Factor Receptor Superfamily Member 1A (TNR1A))
    Autre désignation
    TNR1A
    Sujet
    Receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Contributes to the induction of non-cytocidal TNF effects including anti-viral state and activation of the acid sphingomyelinase.
    Poids moléculaire
    47.6 kDa
    UniProt
    P19438
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