TNRC6A Anticorps
(Trinucleotide Repeat Containing 6A (TNRC6A))
This gene encodes a member of the trinucleotide repeat containing 6 protein family. The protein functions in post-transcriptional gene silencing through the RNA interference (RNAi) and microRNA pathways. The protein associates with messenger RNAs and Argonaute proteins in cytoplasmic bodies known as GW-bodies or P-bodies. Inhibiting expression of this gene delocalizes other GW-body proteins and impairs RNAi and microRNA-induced gene silencing. [provided by RefSeq, Jul 2008].
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TNRC6A recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
ELISA, IHC, IF
Validations
- (2)
N° du produit
ABIN7357482
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB
Validations
- (1)
N° du produit
ABIN6243375
Quantité
200 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
ELISA
Validations
N° du produit
ABIN7357485
Quantité
50 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits TNRC6A
: "Crosstalk between alternative polyadenylation and miRNAs in the regulation of protein translational efficiency." dans: Genome research, Vol. 28, Issue 11, pp. 1656-1663, (2019) (PubMed).: "Reassessment of Exosome Composition." dans: Cell, Vol. 177, Issue 2, pp. 428-445.e18, (2019) (PubMed).
: "Regulation of MicroRNA Machinery and Development by Interspecies S-Nitrosylation." dans: Cell, Vol. 176, Issue 5, pp. 1014-1025.e12, (2019) (PubMed).
: "MicroRNAs of miR-17-92 cluster increase gene expression by targeting mRNA-destabilization pathways." dans: Biochimica et biophysica acta. Gene regulatory mechanisms, Vol. 1861, Issue 7, pp. 603-612, (2018) (PubMed).
: "NMDAR-dependent Argonaute 2 phosphorylation regulates miRNA activity and dendritic spine plasticity." dans: The EMBO journal, Vol. 37, Issue 11, (2018) (PubMed).
: "MicroRNAs recruit eIF4E2 to repress translation of target mRNAs." dans: Protein & cell, Vol. 8, Issue 10, pp. 750-761, (2017) (PubMed).
: "CK2 targeted RNAi therapeutic delivered via malignant cell-directed tenfibgen nanocapsule: dose and molecular mechanisms of response in xenograft prostate tumors." dans: Oncotarget, Vol. 7, Issue 38, pp. 61789-61805, (2016) (PubMed).
: "Human 4E-T represses translation of bound mRNAs and enhances microRNA-mediated silencing." dans: Nucleic acids research, Vol. 42, Issue 5, pp. 3298-313, (2014) (PubMed).
: "Ethanol facilitates hepatitis C virus replication via up-regulation of GW182 and heat shock protein 90 in human hepatoma cells." dans: Hepatology (Baltimore, Md.), Vol. 57, Issue 1, pp. 70-80, (2013) (PubMed).
: "Translational repression and eIF4A2 activity are critical for microRNA-mediated gene regulation." dans: Science (New York, N.Y.), Vol. 340, Issue 6128, pp. 82-5, (2013) (PubMed).
Synonymes et noms alternatifs relatifs à TNRC6A
trinucleotide repeat containing 6a (Tnrc6a), trinucleotide repeat containing 6A (TNRC6A), 2010321I05Rik, 3110054G10Rik, AW557223, CAGH26, D130023A07Rik, GW1, GW182, Tnrc6, TNRC6Protein level used designations for TNRC6A
- trinucleotide repeat-containing gene 6A protein
- GW182 autoantigen
- CAG repeat protein 26
- EDIE
- EMSY interactor protein
- glycine-tryptophan protein of 182 kDa
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