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TOPBP1 Produits

(Topoisomerase (DNA) II Binding Protein 1 (TOPBP1))
This gene encodes a binding protein which interacts with the C-terminal region of topoisomerase II beta. This interaction suggests a supportive role for this protein in the catalytic reactions of topoisomerase II beta through transient breakages of DNA strands. [provided by RefSeq, Jul 2008].

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Catégories TOPBP1 en vedette

TOPBP1 Anticorps

High quality antibodies with extensive validation data.

TOPBP1 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

TOPBP1 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB
Validations
  • (1)
  • (4)
N° du produit ABIN6149398
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human, Mouse
Application WB, IHC, IF
Validations
  • (3)
N° du produit ABIN7261736
Quantité 200 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA
Validations
  • (3)
N° du produit ABIN1774839
Quantité 100 μg
Fiche technique Fiche technique

TOPBP1 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1323353
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7419580
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7419823
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits TOPBP1

Wang, Wang, Xin, Wang, Wang, Xu, Jia, Yue, Wang, Song: "Two novel LRR-only proteins in Chlamys farreri: Similar in structure, yet different in expression profile and pattern recognition." dans: Developmental and comparative immunology, Vol. 59, pp. 99-109, (2017) (PubMed).

Choe, Nicolae, Constantin, Imamura Kawasawa, Delgado-Diaz, De, Freire, Smits, Moldovan: "HUWE1 interacts with PCNA to alleviate replication stress." dans: EMBO reports, Vol. 17, Issue 6, pp. 874-86, (2016) (PubMed).

Kumar, Mazzanti, Mistrik, Kosar, Beznoussenko, Mironov, Garrè, Parazzoli, Shivashankar, Scita, Bartek, Foiani: "ATR mediates a checkpoint at the nuclear envelope in response to mechanical stress." dans: Cell, Vol. 158, Issue 3, pp. 633-46, (2014) (PubMed).

Liu, Graves, Scott, Li, Lin: "Akt switches TopBP1 function from checkpoint activation to transcriptional regulation through phosphoserine binding-mediated oligomerization." dans: Molecular and cellular biology, Vol. 33, Issue 23, pp. 4685-700, (2013) (PubMed).

Tomida, Itaya, Shigechi, Unno, Uchida, Ikura, Masuda, Matsuda, Adachi, Kobayashi, Meetei, Maehara, Yamamoto, Kamiya, Matsuura, Matsuda, Ikura, Ishiai, Takata: "A novel interplay between the Fanconi anemia core complex and ATR-ATRIP kinase during DNA cross-link repair." dans: Nucleic acids research, Vol. 41, Issue 14, pp. 6930-41, (2013) (PubMed).

Kuhnert, Schmidt, Monajembashi, Franke, Schlott, Grosse, Greulich, Saluz, Hänel: "Proteomic identification of PSF and p54(nrb) as TopBP1-interacting proteins." dans: Journal of cellular biochemistry, Vol. 113, Issue 5, pp. 1744-53, (2012) (PubMed).

Ohlenschläger, Kuhnert, Schneider, Haumann, Bellstedt, Keller, Saluz, Hortschansky, Hänel, Grosse, Görlach, Pospiech: "The N-terminus of the human RecQL4 helicase is a homeodomain-like DNA interaction motif." dans: Nucleic acids research, Vol. 40, Issue 17, pp. 8309-24, (2012) (PubMed).

Lee, Katyal, Downing, Zhao, Russell, McKinnon: "Neurogenesis requires TopBP1 to prevent catastrophic replicative DNA damage in early progenitors." dans: Nature neuroscience, Vol. 15, Issue 6, pp. 819-26, (2012) (PubMed).

Al-Khalaf, Hendrayani, Aboussekhra: "The atr protein kinase controls UV-dependent upregulation of p16INK4A through inhibition of Skp2-related polyubiquitination/degradation." dans: Molecular cancer research : MCR, Vol. 9, Issue 3, pp. 311-9, (2011) (PubMed).

Forrester, Sedgwick, Thomas, Blackford, Speiseder, Dobner, Byrd, Stewart, Turnell, Grand: "Serotype-specific inactivation of the cellular DNA damage response during adenovirus infection." dans: Journal of virology, Vol. 85, Issue 5, pp. 2201-11, (2011) (PubMed).

Synonymes et noms alternatifs relatifs à TOPBP1

DNA topoisomerase II binding protein 1 (Topbp1), DNA topoisomerase II binding protein 1 (topbp1), topoisomerase (DNA) II binding protein 1 (TOPBP1), DNA topoisomerase II binding protein 1 (TOPBP1), dna topoisomerase ii binding protein 1 (IC) (topbp1), transcription coactivator (MEI1), topoisomerase (DNA) II binding protein 1 (Topbp1), DNA topoisomerase II binding protein 1 L homeolog (topbp1.L), 1110031N14Rik, 2810429C13Rik, AI256758, cut5, D430026L04Rik, F2P24.3, F2P24_3, meiosis defective 1, mKIAA0259, mus101, RGD1562949, TOP2BP1, top2bp1, TOPBP1, TopBP1-A, TopBP1-B, Xmus101, XtopBP

Protein level used designations for TOPBP1

  • DNA topoisomerase 2-binding protein 1
  • topoisomerase (DNA) II beta binding protein
  • topoisomerase (DNA) II binding protein 1
  • dna topoisomerase ii binding protein 1 (IC)
  • DNA topoisomerase 2-binding protein 1-like
  • DNA topoisomerase II-beta-binding protein 1
  • DNA topoisomerase II-binding protein 1
  • Cut5-related protein
  • DNA topoisomerase 2-binding protein 1-A
  • DNA topoisomerase 2-binding protein 1-B
  • DNA topoisomerase II-binding protein 1-A
  • DNA topoisomerase II-binding protein 1-B
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