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Topoisomerase I Produits

(Topoisomerase (DNA) I (TOP1))
This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus altering the topology of DNA. This gene is localized to chromosome 20 and has pseudogenes which reside on chromosomes 1 and 22. [provided by RefSeq, Jul 2008].

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Catégories Topoisomerase I en vedette

Topoisomerase I Anticorps

High quality antibodies with extensive validation data.

Topoisomerase I Kits ELISA

Reliable ELISA kits for a wide range of species.

Topoisomerase I Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

Topoisomerase I recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, ELISA, IHC (p)
Validations
  • (1)
  • (8)
N° du produit ABIN563222
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC, IF, IP
Validations
  • (7)
N° du produit ABIN7270850
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IHC, IP, FACS
Validations
  • (5)
N° du produit ABIN7127850
Quantité 100 μL
Fiche technique Fiche technique

Topoisomerase I recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
N° du produit ABIN6960049
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6970752
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6970753
Quantité 96 tests
Fiche technique Fiche technique

Topoisomerase I recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1323345
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7413022
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7396097
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits Topoisomerase I

Kim, Tan, Liu, Trahair, Liu, Haber, Norris, Marshall, Cheung: "High TDP43 expression is required for TRIM16-induced inhibition of cancer cell growth and correlated with good prognosis of neuroblastoma and breast cancer patients." dans: Cancer letters, Vol. 374, Issue 2, pp. 315-23, (2016) (PubMed).

Xu, Chen, Wang, Xu, Yuan, Li, Bai, Xue: "Inhibitory effects of lapachol on rat C6 glioma in vitro and in vivo by targeting DNA topoisomerase I and topoisomerase II." dans: Journal of experimental & clinical cancer research : CR, Vol. 35, Issue 1, pp. 178, (2016) (PubMed).

Kim, Rahmanto, Tan, Norris, Haber, Marshall, Cheung: "TRIM16 overexpression induces apoptosis through activation of caspase-2 in cancer cells." dans: Apoptosis : an international journal on programmed cell death, Vol. 18, Issue 5, pp. 639-51, (2013) (PubMed).

Kobayashi, Aida, Nagaoka, Begum, Kitawaki, Nakata, Stanlie, Doi, Kato, Okazaki, Shinkura, Muramatsu, Kinoshita, Honjo: "AID-induced decrease in topoisomerase 1 induces DNA structural alteration and DNA cleavage for class switch recombination." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 52, pp. 22375-80, (2010) (PubMed).

Deloukas, Matthews, Ashurst, Burton, Gilbert, Jones, Stavrides, Almeida, Babbage, Bagguley, Bailey, Barlow, Bates, Beard, Beare, Beasley, Bird, Blakey, Bridgeman, Brown, Buck, Burrill, Butler, Carder et al.: "The DNA sequence and comparative analysis of human chromosome 20. ..." dans: Nature, Vol. 414, Issue 6866, pp. 865-71, (2002) (PubMed).

Tazi, Rossi, Labourier, Gallouzi, Brunel, Antoine: "DNA topoisomerase I: customs officer at the border between DNA and RNA worlds?" dans: Journal of molecular medicine (Berlin, Germany), Vol. 75, Issue 11-12, pp. 786-800, (1998) (PubMed).

Kunze, Yang, Dölberg, Sundarp, Knippers, Richter: "Structure of the human type I DNA topoisomerase gene." dans: The Journal of biological chemistry, Vol. 266, Issue 15, pp. 9610-6, (1991) (PubMed).

Sugimoto, Tsukahara, Oh-hara, Isoe, Tsuruo: "Decreased expression of DNA topoisomerase I in camptothecin-resistant tumor cell lines as determined by a monoclonal antibody." dans: Cancer research, Vol. 50, Issue 21, pp. 6925-30, (1990) (PubMed).

Synonymes et noms alternatifs relatifs à Topoisomerase I

Topoisomerase 1 (Top1), DNA topoisomerase I (top1), DNA topoisomerase I (topA), DNA topoisomerase I (ZMO1193), DNA topoisomerase I (MRAD2831_RS63095), DNA topoisomerase I (Lferr_0016), DNA topoisomerase I (PC1_2015), DNA topoisomerase I (Za10_0136), DNA topoisomerase I (Gbro_0575), DNA topoisomerase I (Dd586_2108), DNA topoisomerase I (Kvar_3044), DNA topoisomerase I (Alvin_2069), DNA topoisomerase I (Dacet_0849), DNA topoisomerase I (Mrub_1615), DNA topoisomerase I (Arnit_2962), DNA topoisomerase I (Ndas_4953), DNA topoisomerase I (Trad_2377), DNA topoisomerase I (Acear_1653), DNA topoisomerase I (Mahau_0844), DNA topoisomerase I (Mesop_4109), DNA topoisomerase I (Thein_1586), DNA topoisomerase I (Theth_0241), DNA topoisomerase I alpha (TOP1ALPHA), DNA topoisomerase 1 (top-1), DNA topoisomerase I (TOP1), topoisomerase (DNA) I (Top1), DNA topoisomerase I (Top1), DNA topoisomerase I, gene 1 L homeolog (top1.1.L), Ab2-086, AI467334, CG6146, D130064I21Rik, Dmel\\CG6146, DNA topoisomerase 1 beta, DNA topoisomerase I alpha, dTopoI, l(1)G0134, l(1)G0201, l(1)G0229, l(1)G0278, l(1)top1, MGO1, MGOUN 1, MTE17.1, MTE17_1, Top-1, TOP1, top1, TOP1BETA, TopI, TOPI, topi, Topo I, TopoI, topo I, topoI, TOPOISOMERASE 1

Protein level used designations for Topoisomerase I

  • CG6146-PA
  • CG6146-PB
  • CG6146-PC
  • CG6146-PD
  • Top1-PA
  • Top1-PB
  • Top1-PC
  • Top1-PD
  • topoisomerase 1
  • topoisomerase I
  • topoisomerase1
  • type I topoisomerase
  • DNA topoisomerase I
  • DNA topoisomerase 1
  • type I DNA topoisomerase
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