TPMT Produits
(Thiopurine S-Methyltransferase (TPMT))
Catégories
This gene encodes the enzyme that metabolizes thiopurine drugs via S-adenosyl-L-methionine as the S-methyl donor and S-adenosyl-L-homocysteine as a byproduct. Thiopurine drugs such as 6-mercaptopurine are used as chemotherapeutic agents. Genetic polymorphisms that affect this enzymatic activity are correlated with variations in sensitivity and toxicity to such drugs within individuals. A pseudogene for this locus is located on chromosome 18q. [provided by RefSeq, Jul 2008].
antibodies-online.com est synonyme de produits de recherche de haute qualité. Cherchez, trouvez et commandez des outils avec des données de validation étendues, des images, des références. Notre service clientèle scientifique est toujours à votre disposition si vous avez des questions sur la sélection ou l'application de nos produits.
Catégories TPMT en vedette
TPMT Anticorps
High quality antibodies with extensive validation data.
TPMT Kits ELISA
Reliable ELISA kits for a wide range of species.
TPMT Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
TPMT recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (7)
N° du produit
ABIN7435148
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, IF, IHC (p)
Validations
- (2)
- (5)
N° du produit
ABIN563239
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Dog, Human
Application
WB, IHC, IHC (p), FACS
Validations
- (6)
N° du produit
ABIN1501480
Quantité
100 μL
Fiche technique
Fiche technique
TPMT recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6970609
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6962695
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6959901
Quantité
96 tests
Fiche technique
Fiche technique
TPMT recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1323441
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN934951
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7396802
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits TPMT
: "Sorting nexin 27 interacts with multidrug resistance-associated protein 4 (MRP4) and mediates internalization of MRP4." dans: The Journal of biological chemistry, Vol. 287, Issue 18, pp. 15054-65, (2012) (PubMed).: "S-adenosylmethionine regulates thiopurine methyltransferase activity and decreases 6-mercaptopurine cytotoxicity in MOLT lymphoblasts." dans: Biochemical pharmacology, Vol. 77, Issue 12, pp. 1845-53, (2009) (PubMed).
: "A novel gene delivery system for stable transfection of thiopurine-S-methyltransferase gene in versatile cell types." dans: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V, Vol. 69, Issue 1, pp. 23-30, (2008) (PubMed).
: "Human thiopurine S-methyltransferase pharmacogenetics: variant allozyme misfolding and aggresome formation." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 102, Issue 26, pp. 9394-9, (2005) (PubMed).
: "Stimulation of E2F1/DP1 transcriptional activity by MDM2 oncoprotein." dans: Nature, Vol. 375, Issue 6533, pp. 691-4, (1995) (PubMed).
Synonymes et noms alternatifs relatifs à TPMT
thiopurine S-methyltransferase L homeolog (tpmt.L), thiopurine S-methyltransferase, tandem duplicate 2 (tpmt.2), thiopurine S-methyltransferase TpmT (tpmT), thiopurine S-methyltransferase (MCA0794), thiopurine S-methyltransferase (Pnap_4948), thiopurine S-methyltransferase (Hhal_1383), thiopurine S-methyltransferase (TK90_1044), thiopurine S-methyltransferase (Slit_1144), thiopurine S-methyltransferase (Tint_0842), Thiopurine S-methyltransferase (Fbal_3334), thiopurine S-methyltransferase (Celly_3188), thiopurine S-methyltransferase (Weevi_1737), Thiopurine S-methyltransferase (Psefu_2696), Thiopurine S-methyltransferase (Metme_3860), thiopurine methyltransferase (Tpmt), thiopurine S-methyltransferase (TPMT), thiopurine S-methyltransferase (Tpmt), AW106912, MGC84277, NHLRC1Protein level used designations for TPMT
- thiopurine S-methyltransferase
- Thiopurine S-methyltransferase
- S-adenosyl-L-methionine:thiopurine S-methyltransferase
- thiopurine methyltransferase
- NHL repeat containing 1
Vous êtes ici:
