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TRAF3 Produits

(TNF Receptor-Associated Factor 3 (TRAF3))

Catégories

The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from, members of the TNF receptor (TNFR) superfamily. This protein participates in the signal transduction of CD40, a TNFR family member important for the activation of the immune response. This protein is found to be a critical component of the lymphotoxin-beta receptor (LTbetaR) signaling complex, which induces NF-kappaB activation and cell death initiated by LTbeta ligation. Epstein-Barr virus encoded latent infection membrane protein-1 (LMP1) can interact with this and several other members of the TRAF family, which may be essential for the oncogenic effects of LMP1. Several alternatively spliced transcript variants encoding three distinct isoforms have been reported. [provided by RefSeq, Dec 2010].

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Catégories TRAF3 en vedette

TRAF3 Anticorps

High quality antibodies with extensive validation data.

TRAF3 Kits ELISA

Reliable ELISA kits for a wide range of species.

TRAF3 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

TRAF3 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Mouse
Application WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
  • (5)
N° du produit ABIN738921
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IF
Validations
  • (2)
N° du produit ABIN7172236
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human, Mouse
Application WB
Validations
  • (2)
N° du produit ABIN657866
Quantité 400 μL
Fiche technique Fiche technique

TRAF3 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6960018
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN5690963
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Semi-Quantitative Sandwich ELISA
Validations
N° du produit ABIN6385595
Quantité 96 tests
Fiche technique Fiche technique

TRAF3 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN7125408
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1323499
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1323497
Quantité 10 μg
Fiche technique Fiche technique

Dernières publications sur nos produits TRAF3

Agrawal, Rastogi, Dogra, Pandey, Basu, Singh: "Chandipura virus changes cellular miRNome in human microglial cells." dans: Journal of medical virology, (2019) (PubMed).

Lin, Yi, Stunz, Maine, Sherman, Bishop: "The adaptor protein TRAF3 inhibits interleukin-6 receptor signaling in B cells to limit plasma cell development." dans: Science signaling, Vol. 8, Issue 392, pp. ra88, (2015) (PubMed).

Yi, Lin, Stunz, Bishop: "The adaptor TRAF3 restrains the lineage determination of thymic regulatory T cells by modulating signaling via the receptor for IL-2." dans: Nature immunology, Vol. 15, Issue 9, pp. 866-74, (2014) (PubMed).

Tsao, Lodish, Fruebis: "ACRP30, a new hormone controlling fat and glucose metabolism." dans: European journal of pharmacology, Vol. 440, Issue 2-3, pp. 213-21, (2002) (PubMed).

Zapata, Krajewska, Krajewski, Kitada, Welsh, Monks, McCloskey, Gordon, Kipps, Gascoyne, Shabaik, Reed: "TNFR-associated factor family protein expression in normal tissues and lymphoid malignancies." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 165, Issue 9, pp. 5084-96, (2000) (PubMed).

van Eyndhoven, Gamper, Cho, Mackus, Lederman: "TRAF-3 mRNA splice-deletion variants encode isoforms that induce NF-kappaB activation." dans: Molecular immunology, Vol. 36, Issue 10, pp. 647-58, (1999) (PubMed).

Xu, Cheng, Baltimore: "Targeted disruption of TRAF3 leads to postnatal lethality and defective T-dependent immune responses." dans: Immunity, Vol. 5, Issue 5, pp. 407-15, (1997) (PubMed).

Cheng, Cleary, Ye, Hong, Lederman, Baltimore: "Involvement of CRAF1, a relative of TRAF, in CD40 signaling." dans: Science (New York, N.Y.), Vol. 267, Issue 5203, pp. 1494-8, (1995) (PubMed).

Synonymes et noms alternatifs relatifs à TRAF3

TNF receptor associated factor 3 (TRAF3), TNF receptor-associated factor 3 (Traf3), Tnf receptor-associated factor 3 (Traf3), AI528849, amn, CAP-1, CAP1, CD40bp, CRAF1, IIAE5, LAP1, T-BAM

Protein level used designations for TRAF3

  • CD40 associated protein 1
  • CD40 binding protein
  • CD40 receptor associated factor 1
  • LMP1-associated protein 1
  • CD40 receptor-associated factor 1
  • TRAFAMN
  • TNF receptor-associated factor 3
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