Transforming Growth Factor, beta 2 Produits
(Transforming Growth Factor, beta 2 (TGFB2))
Catégories
This gene encodes a member of the transforming growth factor beta (TGFB) family of cytokines, which are multifunctional peptides that regulate proliferation, differentiation, adhesion, migration, and other functions in many cell types by transducing their signal through combinations of transmembrane type I and type II receptors (TGFBR1 and TGFBR2) and their downstream effectors, the SMAD proteins. Disruption of the TGFB/SMAD pathway has been implicated in a variety of human cancers. The encoded protein is secreted and has suppressive effects of interleukin-2 dependent T-cell growth. Translocation t(1\;7)(q41\;p21) between this gene and HDAC9 is associated with Peters' anomaly, a congenital defect of the anterior chamber of the eye. The knockout mice lacking this gene show perinatal mortality and a wide range of developmental, including cardiac, defects. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Sep 2010].
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Catégories Transforming Growth Factor, beta 2 en vedette
Transforming Growth Factor, beta 2 Anticorps
High quality antibodies with extensive validation data.
Transforming Growth Factor, beta 2 Kits ELISA
Reliable ELISA kits for a wide range of species.
Transforming Growth Factor, beta 2 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
Transforming Growth Factor, beta 2 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IHC, ELISA, IF
Validations
- (6)
N° du produit
ABIN3029221
Quantité
0.4 mL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (4)
N° du produit
ABIN7429457
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Rat
Application
WB, IHC, IP, ICC
Validations
- (4)
N° du produit
ABIN7429460
Quantité
100 μL
Fiche technique
Fiche technique
Transforming Growth Factor, beta 2 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Competition ELISA
Validations
- (1)
- (1)
N° du produit
ABIN6960089
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
N° du produit
ABIN6960093
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6960096
Quantité
96 tests
Fiche technique
Fiche technique
Transforming Growth Factor, beta 2 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Tobacco (Nicotiana benthamiana)
Validations
- (4)
- (2)
N° du produit
ABIN1112028
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
HEK-293 Cells
Validations
- (2)
N° du produit
ABIN7275710
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
HEK-293 Cells
Validations
- (2)
N° du produit
ABIN7275711
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits Transforming Growth Factor, beta 2
: "Crystallins Play a Crucial Role in Glaucoma and Promote Neuronal Cell Survival in an In Vitro Model Through Modulating Müller Cell Secretion." dans: Investigative ophthalmology & visual science, Vol. 63, Issue 8, pp. 3, (2022) (PubMed).: "Angiocrine signals regulate quiescence and therapy resistance in bone metastasis." dans: JCI insight, Vol. 4, Issue 13, (2020) (PubMed).
: "GFI1 downregulation promotes inflammation-linked metastasis of colorectal cancer." dans: Cell death and differentiation, Vol. 24, Issue 5, pp. 929-943, (2018) (PubMed).
: "A microfluidic device for studying chemotaxis mechanism of bacterial cancer targeting." dans: Scientific reports, Vol. 8, Issue 1, pp. 6394, (2018) (PubMed).
: "Plasminogen Activator Inhibitor-1 Protects Mice Against Cardiac Fibrosis by Inhibiting Urokinase-type Plasminogen Activator-mediated Plasminogen Activation." dans: Scientific reports, Vol. 7, Issue 1, pp. 365, (2017) (PubMed).
: "Effects of ranibizumab on TGF-β1 and TGF-β2 production by human Tenon's fibroblasts: An in vitro study." dans: Molecular vision, Vol. 21, pp. 1191-200, (2016) (PubMed).
: "SP600125 promotes resolution of allergic airway inflammation via TLR9 in an OVA-induced murine acute asthma model." dans: Molecular immunology, (2015) (PubMed).
: "Influence of the Expression Level of O6-Alkylguanine-DNA Alkyltransferase on the Formation of DNA Interstrand Crosslinks Induced by Chloroethylnitrosoureas in Cells: A Quantitation Using ..." dans: PLoS ONE, Vol. 10, Issue 3, pp. e0121225, (2015) (PubMed).
: "MicroRNA-26a modulates transforming growth factor beta-1-induced proliferation in human fetal lung fibroblasts." dans: Biochemical and biophysical research communications, Vol. 454, Issue 4, pp. 512-517, (2014) (PubMed).
: "Elevated PLGF contributes to small-cell lung cancer brain metastasis." dans: Oncogene, Vol. 32, Issue 24, pp. 2952-62, (2013) (PubMed).
Synonymes et noms alternatifs relatifs à Transforming Growth Factor, beta 2
transforming growth factor beta 2 (TGFB2), transforming growth factor beta 2 L homeolog (tgfb2.L), transforming growth factor, beta 2 (Tgfb2), transforming growth factor, beta receptor 2 (Tgfbr2), transforming growth factor, beta 2 (tgfb2), transforming growth factor beta 2 (Tgfb2), BB105277, LDS4, MGF, TGF-B2, TGF-beta2, tgf-beta2, Tgf-beta2, TGF-beta 2, Tgfb-2, TGFB2, tgfb2-A, TGFbeta2, Tgfbr2TProtein level used designations for Transforming Growth Factor, beta 2
- BSC-1 cell growth inhibitor
- G-TSF
- cetermin
- glioblastoma-derived T-cell suppressor factor
- polyergin
- transforming growth factor beta-2
- TGF-beta 2
- TGF-beta-2
- prepro-polypeptide
- Transforming growth factor beta-2
- transforming growth factor beta 2
- TGF-beta receptor type II
- TGF-beta receptor type-2
- TGF-beta type II receptor
- TGFR-2
- tbetaR-II
- transforming growth factor beta receptor type II
- transforming growth factor beta, receptor 2
- transforming growth factor, beta receptor 2
- transforming growth factor, beta receptor IIT
- transforming growth factor-b type II receptor
- transforming growth factor-beta receptor type II
- transforming growth factor-beta type II receptor
- tgf beta 2
- transforming growth factor, beta 2
- milk growth factor
- transforming growth factor-beta 2
- transforming growth factor beta-2-like
- TGF beta 2 protein
- transforming growth factor-beta2
- TGF beta 2
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