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TREM2 Produits

(Triggering Receptor Expressed On Myeloid Cells 2 (TREM2))

Catégories

This gene encodes a membrane protein that forms a receptor signaling complex with the TYRO protein tyrosine kinase binding protein. The encoded protein functions in immune response and may be involved in chronic inflammation by triggering the production of constitutive inflammatory cytokines. Defects in this gene are a cause of polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Nov 2012].

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Catégories TREM2 en vedette

TREM2 Anticorps

High quality antibodies with extensive validation data.

TREM2 Kits ELISA

Reliable ELISA kits for a wide range of species.

TREM2 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

TREM2 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Rat
Application WB, IHC, IP, ICC
Validations
  • (5)
N° du produit ABIN7443632
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human, Mouse, Pig, Rat
Application WB, ELISA, ICC, IHC (p), IF (p), IHC (fro), IF (cc)
Validations
  • (3)
  • (4)
N° du produit ABIN749678
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Mouse
Application WB, IHC (p)
Validations
  • (4)
N° du produit ABIN1539189
Quantité 400 μL
Fiche technique Fiche technique

TREM2 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6974840
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6999586
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6960173
Quantité 96 tests
Fiche technique Fiche technique

TREM2 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (3)
N° du produit ABIN7275789
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (3)
N° du produit ABIN7275790
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Cynomolgus
Source HEK-293 Cells
Validations
  • (2)
N° du produit ABIN7275786
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits TREM2

Abdi, Pasbakhsh, Shabani, Nekoonam, Sadeghi, Fathi, Abouzaripour, Mohamed, Zibara, Kashani, Zendedel: "Metformin Therapy Attenuates Pro-inflammatory Microglia by Inhibiting NF-κB in Cuprizone Demyelinating Mouse Model of Multiple Sclerosis." dans: Neurotoxicity research, (2021) (PubMed).

Banerjee, Ambler, Keshavan, Paterson, Foiani, Toombs, Heslegrave, Dickson, Fraioli, Groves, Lunn, Fox, Zetterberg, Schott, Werring: "Cerebrospinal Fluid Biomarkers in Cerebral Amyloid Angiopathy." dans: Journal of Alzheimer's disease : JAD, Vol. 74, Issue 4, pp. 1189-1201, (2020) (PubMed).

Manich, Gómez-López, Almolda, Villacampa, Recasens, Shrivastava, González, Castellano: "Differential Roles of TREM2+ Microglia in Anterograde and Retrograde Axonal Injury Models." dans: Frontiers in cellular neuroscience, Vol. 14, pp. 567404, (2020) (PubMed).

Hall, Agrawal: "Increased TREM-2 expression on the subsets of CD11c+ cells in the lungs and lymph nodes during allergic airway inflammation." dans: Scientific reports, Vol. 7, Issue 1, pp. 11853, (2019) (PubMed).

Henjum, Quist-Paulsen, Zetterberg, Blennow, Nilsson, Watne: "CSF sTREM2 in delirium-relation to Alzheimer's disease CSF biomarkers Aβ42, t-tau and p-tau." dans: Journal of neuroinflammation, Vol. 15, Issue 1, pp. 304, (2019) (PubMed).

Zhong, Xu, Zhuo, Wang, Wang, Huang, Wang, Gao, Zhu, Sheng, Chen, Wang, Zhu, Can, Marten, Shinohara, Liu, Du, Sun, Wen, Xu, Bu, Chen: "Soluble TREM2 ameliorates pathological phenotypes by modulating microglial functions in an Alzheimer's disease model." dans: Nature communications, Vol. 10, Issue 1, pp. 1365, (2019) (PubMed).

Jensen, Bahl, Østergaard, Høgh, Wermuth, Heslegrave, Zetterberg, Heegaard, Hasselbalch, Simonsen: "Exercise as a potential modulator of inflammation in patients with Alzheimer's disease measured in cerebrospinal fluid and plasma." dans: Experimental gerontology, Vol. 121, pp. 91-98, (2019) (PubMed).

Nordengen, Kirsebom, Henjum, Selnes, Gísladóttir, Wettergreen, Torsetnes, Grøntvedt, Waterloo, Aarsland, Nilsson, Fladby: "Glial activation and inflammation along the Alzheimer's disease continuum." dans: Journal of neuroinflammation, Vol. 16, Issue 1, pp. 46, (2019) (PubMed).

Lee, Daggett, Gu, Jiang, Langfelder, Li, Wang, Zhao, Park, Cooper, Ferando, Mody, Coppola, Xu, Yang: "Elevated TREM2 Gene Dosage Reprograms Microglia Responsivity and Ameliorates Pathological Phenotypes in Alzheimer's Disease Models." dans: Neuron, Vol. 97, Issue 5, pp. 1032-1048.e5, (2019) (PubMed).

Zhao, Wu, Li, Jiang, Gui, Liu, Sun, Zhu, Piña-Crespo, Zhang, Zhang, Chen, Bu, An, Huang, Xu: "TREM2 Is a Receptor for β-Amyloid that Mediates Microglial Function." dans: Neuron, Vol. 97, Issue 5, pp. 1023-1031.e7, (2019) (PubMed).

Synonymes et noms alternatifs relatifs à TREM2

triggering receptor expressed on myeloid cells 2 (TREM2), triggering receptor expressed on myeloid cells 2 (trem2), trem-like transcript 2 protein (LOC100228399), triggering receptor expressed on myeloid cells 2 (Trem2), trem-2, TREM-2, TREM-A1, TREM-B1, TREM2, trem2a, Trem2a, trem2b, Trem2b, trem2c, Trem2c

Protein level used designations for TREM2

  • triggering receptor expressed on myeloid cells 2
  • triggering receptor expressed on monocytes 2
  • triggering receptor expressed on myeloid cells 2a
  • triggering receptor expressed on myeloid cells 2b
  • triggering receptor expressed on myeloid cells 2c
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