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TRIB2 Produits

(Tribbles Pseudokinase 2 (TRIB2))

Catégories

This gene encodes one of three members of the Tribbles family. The Tribbles members share a Trb domain, which is homologous to protein serine-threonine kinases, but lacks the active site lysine and probably lacks a catalytic function. The Tribbles proteins interact and modulate the activity of signal transduction pathways in a number of physiological and pathological processes. This Tribbles member induces apoptosis of cells mainly of the hematopoietic origin. It has been identified as a protein up-regulated by inflammatory stimuli in myeloid (THP-1) cells, and also as an oncogene that inactivates the transcription factor C/EBPalpha (CCAAT/enhancer-binding protein alpha) and causes acute myelogenous leukemia. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2009].

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Catégories TRIB2 en vedette

TRIB2 Anticorps

High quality antibodies with extensive validation data.

TRIB2 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

TRIB2 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, ELISA, IHC (p), RNAi
Validations
  • (3)
  • (6)
N° du produit ABIN565396
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
  • (3)
N° du produit ABIN716546
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC (p), FACS
Validations
  • (3)
N° du produit ABIN652876
Quantité 400 μL
Fiche technique Fiche technique

TRIB2 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN6209170
Quantité 96 tests
Fiche technique Fiche technique

TRIB2 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
N° du produit ABIN1323589
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1323591
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Baculovirus infected Insect Cells
Validations
  • (1)
N° du produit ABIN7198335
Quantité 50 μg
Fiche technique Fiche technique

Dernières publications sur nos produits TRIB2

Xu, Tong, Huang, Zhang, Qiao, Weng, Liu, Wang, Sun: "TRIB2 inhibits Wnt/?-Catenin/TCF4 signaling through its associated ubiquitin E3 ligases, ?-TrCP, COP1 and Smurf1, in liver cancer cells." dans: FEBS letters, Vol. 588, Issue 23, pp. 4334-41, (2014) (PubMed).

Sung, Francis, Arnold, Holland, Ernst, Angyal, Kiss-Toth: "Enhanced macrophage tribbles-1 expression in murine experimental atherosclerosis." dans: Biology, Vol. 1, Issue 1, pp. 43-57, (2014) (PubMed).

Wang, Zhang, Weng, Qiao, Ma, Xiao, Yu, Pan, Sun et al.: "Impaired phosphorylation and ubiquitination by p70 S6 kinase (p70S6K) and Smad ubiquitination regulatory factor 1 (Smurf1) promote tribbles homolog 2 (TRIB2) stability and carcinogenic property in ..." dans: The Journal of biological chemistry, Vol. 288, Issue 47, pp. 33667-81, (2013) (PubMed).

Qiao, Zhang, Wang: "Ubiquitin E3 ligase SCF(?-TRCP) regulates TRIB2 stability in liver cancer cells." dans: Biochemical and biophysical research communications, Vol. 441, Issue 3, pp. 555-9, (2013) (PubMed).

Synonymes et noms alternatifs relatifs à TRIB2

tribbles pseudokinase 2 (TRIB2), tribbles pseudokinase 2 (trib2), tribbles pseudokinase 2 S homeolog (trib2.S), tribbles pseudokinase 2 (Trib2), AW319517, c5fw, C5FW, gs3955, GS3955, RGD1564451, TRB-2, Trb2, trb2, TRB2, TRIB2, xtrb2, Xtrbl

Protein level used designations for TRIB2

  • tribbles homolog 2 (Drosophila)
  • tribbles homolog 2-like
  • tribbles homolog 2
  • serine/threonine protein kinase
  • tribbles-like protein 2
  • TRB-2
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