TRIB2 Produits
(Tribbles Pseudokinase 2 (TRIB2))
Catégories
This gene encodes one of three members of the Tribbles family. The Tribbles members share a Trb domain, which is homologous to protein serine-threonine kinases, but lacks the active site lysine and probably lacks a catalytic function. The Tribbles proteins interact and modulate the activity of signal transduction pathways in a number of physiological and pathological processes. This Tribbles member induces apoptosis of cells mainly of the hematopoietic origin. It has been identified as a protein up-regulated by inflammatory stimuli in myeloid (THP-1) cells, and also as an oncogene that inactivates the transcription factor C/EBPalpha (CCAAT/enhancer-binding protein alpha) and causes acute myelogenous leukemia. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2009].
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Catégories TRIB2 en vedette
TRIB2 Anticorps
High quality antibodies with extensive validation data.
TRIB2 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
TRIB2 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC (p), RNAi
Validations
- (3)
- (6)
N° du produit
ABIN565396
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
- (3)
N° du produit
ABIN716546
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC (p), FACS
Validations
- (3)
N° du produit
ABIN652876
Quantité
400 μL
Fiche technique
Fiche technique
TRIB2 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN6209170
Quantité
96 tests
Fiche technique
Fiche technique
TRIB2 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
- (1)
N° du produit
ABIN1323589
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1323591
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Baculovirus infected Insect Cells
Validations
- (1)
N° du produit
ABIN7198335
Quantité
50 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits TRIB2
: "TRIB2 inhibits Wnt/?-Catenin/TCF4 signaling through its associated ubiquitin E3 ligases, ?-TrCP, COP1 and Smurf1, in liver cancer cells." dans: FEBS letters, Vol. 588, Issue 23, pp. 4334-41, (2014) (PubMed).: "Enhanced macrophage tribbles-1 expression in murine experimental atherosclerosis." dans: Biology, Vol. 1, Issue 1, pp. 43-57, (2014) (PubMed).
: "Impaired phosphorylation and ubiquitination by p70 S6 kinase (p70S6K) and Smad ubiquitination regulatory factor 1 (Smurf1) promote tribbles homolog 2 (TRIB2) stability and carcinogenic property in ..." dans: The Journal of biological chemistry, Vol. 288, Issue 47, pp. 33667-81, (2013) (PubMed).
: "Ubiquitin E3 ligase SCF(?-TRCP) regulates TRIB2 stability in liver cancer cells." dans: Biochemical and biophysical research communications, Vol. 441, Issue 3, pp. 555-9, (2013) (PubMed).
Synonymes et noms alternatifs relatifs à TRIB2
tribbles pseudokinase 2 (TRIB2), tribbles pseudokinase 2 (trib2), tribbles pseudokinase 2 S homeolog (trib2.S), tribbles pseudokinase 2 (Trib2), AW319517, c5fw, C5FW, gs3955, GS3955, RGD1564451, TRB-2, Trb2, trb2, TRB2, TRIB2, xtrb2, XtrblProtein level used designations for TRIB2
- tribbles homolog 2 (Drosophila)
- tribbles homolog 2-like
- tribbles homolog 2
- serine/threonine protein kinase
- tribbles-like protein 2
- TRB-2
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