TRIM5 Produits
(Tripartite Motif Containing 5 (TRIM5))
Catégories
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein forms homo-oligomers via the coilel-coil region and localizes to cytoplasmic bodies. It appears to function as a E3 ubiquitin-ligase and ubiqutinates itself to regulate its subcellular localization. It may play a role in retroviral restriction. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Dec 2009].
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Catégories TRIM5 en vedette
TRIM5 Anticorps
High quality antibodies with extensive validation data.
TRIM5 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
TRIM5 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (7)
N° du produit
ABIN184983
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB
Validations
- (6)
N° du produit
ABIN2778419
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (3)
- (3)
N° du produit
ABIN969443
Quantité
100 μL
Fiche technique
Fiche technique
TRIM5 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN6211786
Quantité
96 tests
Fiche technique
Fiche technique
TRIM5 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1323702
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1323704
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7319116
Quantité
50 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits TRIM5
: "Stabilized human TRIM5α protects human T cells from HIV-1 infection." dans: Molecular therapy : the journal of the American Society of Gene Therapy, Vol. 22, Issue 6, pp. 1084-95, (2014) (PubMed).: "Type I interferon responses in rhesus macaques prevent SIV infection and slow disease progression. ..." dans: Nature, Vol. 511, Issue 7511, pp. 601-5, (2014) (PubMed).
: "Determinants of the higher order association of the restriction factor TRIM5alpha and other tripartite motif (TRIM) proteins." dans: The Journal of biological chemistry, Vol. 286, Issue 32, pp. 27959-70, (2011) (PubMed).
: "Restriction of foamy viruses by primate Trim5alpha." dans: Journal of virology, Vol. 82, Issue 11, pp. 5429-39, (2008) (PubMed).
: "The design of artificial retroviral restriction factors." dans: Virology, Vol. 365, Issue 2, pp. 302-14, (2007) (PubMed).
: "All three variable regions of the TRIM5alpha B30.2 domain can contribute to the specificity of retrovirus restriction." dans: Journal of virology, Vol. 80, Issue 17, pp. 8554-65, (2006) (PubMed).
: "Retrovirus restriction by TRIM5alpha variants from Old World and New World primates." dans: Journal of virology, Vol. 79, Issue 7, pp. 3930-7, (2005) (PubMed).
: "Cyclophilin A is required for TRIM5{alpha}-mediated resistance to HIV-1 in Old World monkey cells." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 102, Issue 41, pp. 14849-53, (2005) (PubMed).
: "The human and African green monkey TRIM5alpha genes encode Ref1 and Lv1 retroviral restriction factor activities." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 29, pp. 10780-5, (2004) (PubMed).
: "The cytoplasmic body component TRIM5alpha restricts HIV-1 infection in Old World monkeys." dans: Nature, Vol. 427, Issue 6977, pp. 848-53, (2004) (PubMed).
Synonymes et noms alternatifs relatifs à TRIM5
tripartite motif containing 5 (TRIM5), tripartite motif-containing 5 (Trim5), EG667823, Gm8833, RGD1304579, RNF88, TRIM5, TRIM5alphaProtein level used designations for TRIM5
- tripartite motif-containing 5
- TRIM5alpha
- tripartite motif-containing 5 alpha
- tripartite motif-containing protein 5
- tri-partite motif protein 5
- ring finger protein 88
- tripartite motif containing 5 transcript variant iota
- tripartite motif containing 5 transcript variant kappa
- tripartite motif protein TRIM5
- tripartite motif-containing protein 5 isoform alpha
- TRIM5 alpha
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