TRPM2 Produits
(Transient Receptor Potential Cation Channel, Subfamily M, Member 2 (TRPM2))
Catégories
The protein encoded by this gene is a calcium-permeable cation channel that is regulated by free intracellular ADP-ribose. The encoded protein is activated by oxidative stress and confers susceptibility to cell death. Several alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Jul 2008].
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Catégories TRPM2 en vedette
TRPM2 Anticorps
High quality antibodies with extensive validation data.
TRPM2 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
IHC, WB, ELISA, IF
Validations
- (6)
N° du produit
ABIN7172859
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
IHC, WB, ELISA
Validations
- (3)
N° du produit
ABIN7172857
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC (p)
Validations
- (3)
N° du produit
ABIN2856853
Quantité
100 μL
Fiche technique
Fiche technique
Dernières publications sur nos produits TRPM2
: "Novel CaM-binding motif in its NudT9H domain contributes to temperature sensitivity of TRPM2." dans: Biochimica et biophysica acta. Molecular cell research, (2018) (PubMed).: "Paradoxical lower sensitivity of Locus Coeruleus than Substantia Nigra pars compacta neurons to acute actions of rotenone." dans: Experimental neurology, Vol. 287, Issue Pt 1, pp. 34-43, (2016) (PubMed).
: "The role of TRPM2 in hydrogen peroxide-induced expression of inflammatory cytokine and chemokine in rat trigeminal ganglia." dans: Neuroscience, Vol. 297, pp. 160-9, (2015) (PubMed).
: "ADP-ribose/TRPM2-mediated Ca2+ signaling is essential for cytolytic degranulation and antitumor activity of natural killer cells." dans: Scientific reports, Vol. 5, pp. 9482, (2015) (PubMed).
: "The enzymatic activities of CD38 enhance CLL growth and trafficking: implications for therapeutic targeting." dans: Leukemia, Vol. 29, Issue 2, pp. 356-68, (2015) (PubMed).
: "TNF-α-mediated caspase-8 activation induces ROS production and TRPM2 activation in adult ventricular myocytes." dans: Cardiovascular research, Vol. 103, Issue 1, pp. 90-9, (2014) (PubMed).
: "Oxidative stress increases pulmonary vascular permeability in diabetic rats through activation of transient receptor potential melastatin 2 channels." dans: Microcirculation (New York, N.Y. : 1994), Vol. 21, Issue 8, pp. 754-60, (2014) (PubMed).
: "Structure-activity relationship of adenosine 5'-diphosphoribose at the transient receptor potential melastatin 2 (TRPM2) channel: rational design of antagonists." dans: Journal of medicinal chemistry, Vol. 56, Issue 24, pp. 10079-102, (2013) (PubMed).
: "TRPM2 cation channels modulate T cell effector functions and contribute to autoimmune CNS inflammation." dans: PLoS ONE, Vol. 7, Issue 10, pp. e47617, (2012) (PubMed).
: "Expression and functional properties of TRPM2 channels in dopaminergic neurons of the substantia nigra of the rat." dans: Journal of neurophysiology, Vol. 106, Issue 6, pp. 2865-75, (2011) (PubMed).
Synonymes et noms alternatifs relatifs à TRPM2
transient receptor potential cation channel subfamily M member 2 (TRPM2), transient receptor potential cation channel, subfamily M, member 2 (Trpm2), transient receptor potential cation channel, subfamily M, member 2 (trpm2), transient receptor potential cation channel subfamily C member 7 (TRPC7), transient receptor potential cation channel subfamily M member 2 (trpm2), transient receptor potential cation channel subfamily M member 2 (Trpm2), 9830168K16Rik, C79133, EREG1, KNP3, LTRPC2, NUDT9H, NUDT9L1, si:ch73-263b18.1, Trp7, TRPC7, TRPM2, Trpm2-predicted, Trrp7Protein level used designations for TRPM2
- LTrpC-2
- estrogen-responsive element-associated gene 1 protein
- long transient receptor potential channel 2
- transient receptor potential cation channel subfamily M member 2
- transient receptor potential channel 7
- transient receptor potential melastatin family 2
- transient receptor potential cation channel, subfamily M, member 2
- transient receptor potential cation channel, subfamily C, member 7
- transient receptor potential cation channel, subfamily C, member 7-like
- transient receptor potential cation channel subfamily M member 2-like
- transient receptor protein 7
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