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TRPM6 Produits

(Transient Receptor Potential Cation Channel, Subfamily M, Member 6 (TRPM6))
This gene is predominantly expressed in the kidney and colon, and encodes a protein containing an ion channel domain and a protein kinase domain. It is crucial for magnesium homeostasis, and plays an essential role in epithelial magnesium transport and in the active magnesium absorption in the gut and kidney. Mutations in this gene are associated with hypomagnesemia with secondary hypocalcemia. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Apr 2010].

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Catégories TRPM6 en vedette

TRPM6 Anticorps

High quality antibodies with extensive validation data.

TRPM6 Kits ELISA

Reliable ELISA kits for a wide range of species.

TRPM6 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

TRPM6 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC (p)
Validations
  • (3)
  • (2)
N° du produit ABIN392616
Quantité 400 μL
Fiche technique Fiche technique
Reactivity Human
Application IHC, ELISA, IF
Validations
  • (2)
N° du produit ABIN7172868
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application IHC, ELISA, WB
Validations
  • (3)
N° du produit ABIN3029237
Quantité 0.4 mL
Fiche technique Fiche technique

TRPM6 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6960126
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN5674671
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN5674672
Quantité 96 tests
Fiche technique Fiche technique

TRPM6 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7398629
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN6383237
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits TRPM6

Furukawa, Fujii, Manabe, Matsunaga, Endo, Hasegawa, Ito, Yamaguchi, Yamazaki, Ikari: "Up-Regulation of Transient Receptor Potential Melastatin 6 Channel Expression by Tumor Necrosis Factor-α in the Presence of Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor." dans: Journal of cellular physiology, Vol. 232, Issue 10, pp. 2841-2850, (2017) (PubMed).

Lee, Chen, Ng, Lai, Lien: "Renal adaptation to gentamicin-induced mineral loss." dans: American journal of nephrology, Vol. 35, Issue 3, pp. 279-86, (2012) (PubMed).

Ikari, Okude, Sawada, Takahashi, Sugatani, Miwa: "Down-regulation of TRPM6-mediated magnesium influx by cyclosporin A." dans: Naunyn-Schmiedeberg's archives of pharmacology, Vol. 377, Issue 4-6, pp. 333-43, (2008) (PubMed).

Ikari, Okude, Sawada, Yamazaki, Sugatani, Miwa: "TRPM6 expression and cell proliferation are up-regulated by phosphorylation of ERK1/2 in renal epithelial cells." dans: Biochemical and biophysical research communications, Vol. 369, Issue 4, pp. 1129-33, (2008) (PubMed).

Cantrell: "Phosphoinositide 3-kinase signalling pathways." dans: Journal of cell science, Vol. 114, Issue Pt 8, pp. 1439-45, (2001) (PubMed).

Blume-Jensen, Hunter: "Oncogenic kinase signalling." dans: Nature, Vol. 411, Issue 6835, pp. 355-65, (2001) (PubMed).

Jhiang: "The RET proto-oncogene in human cancers." dans: Oncogene, Vol. 19, Issue 49, pp. 5590-7, (2000) (PubMed).

Synonymes et noms alternatifs relatifs à TRPM6

transient receptor potential cation channel subfamily M member 6 (TRPM6), transient receptor potential cation channel, subfamily M, member 6 (Trpm6), CHAK2, HMGX, HOMG, HOMG1, HSH, TRPM6, TRPM6/CHAK2

Protein level used designations for TRPM6

  • transient receptor potential cation channel, subfamily M, member 6
  • channel kinase 2
  • melastatin-related TRP cation channel 6
  • transient receptor potential cation channel subfamily M member 6
  • transient receptor potential cation channel 6/channel-kinase 2
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