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TSH receptor Produits

(Thyroid Stimulating Hormone Receptor (TSHR))

Catégories

The protein encoded by this gene is a membrane protein and a major controller of thyroid cell metabolism. The encoded protein is a receptor for thyrothropin and thyrostimulin, and its activity is mediated by adenylate cyclase. Defects in this gene are a cause of several types of hyperthyroidism. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008].

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Catégories TSH receptor en vedette

TSH receptor Anticorps

High quality antibodies with extensive validation data.

TSH receptor Kits ELISA

Reliable ELISA kits for a wide range of species.

TSH receptor Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

TSH receptor recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC
Validations
  • (1)
  • (5)
N° du produit ABIN6149622
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Application WB, ELISA, FACS, IHC (p)
Validations
  • (5)
N° du produit ABIN668901
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Bacteria, Human, Rat
Application ELISA, IHC (p)
Validations
  • (4)
N° du produit ABIN723470
Quantité 100 μL
Fiche technique Fiche technique

TSH receptor recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6970681
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6959969
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Goat
Analytical Method
Validations
N° du produit ABIN996270
Quantité 96 tests
Fiche technique Fiche technique

TSH receptor recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (2)
N° du produit ABIN7491755
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN7125394
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (2)
N° du produit ABIN1330596
Quantité 10 μg
Fiche technique Fiche technique

Dernières publications sur nos produits TSH receptor

Yang, Yi, Zhang, He, He, Wu, Xu, Li, Fan, Zhu, Xue, Zhou: "Generation and characterization of a hypothyroidism rat model with truncated thyroid stimulating hormone receptor." dans: Scientific reports, Vol. 8, Issue 1, pp. 4004, (2018) (PubMed).

Kumata, Nagata, Matsushita, Kuwamoto, Kato, Murakami, Fukata, Hayashi et al.: "Thyrotropin Receptor Antibody (TRAb)-IgM Levels Are Markedly Higher Than TRAb-IgG Levels in Graves' Disease Patients and Controls, and TRAb-IgM Production Is Related to Epstein-Barr Virus ..." dans: Viral immunology, Vol. 29, Issue 8, pp. 459-463, (2016) (PubMed).

Nagata, Nakayama, Higaki, Ochi, Kanai, Matsushita, Kuwamoto, Kato, Murakami, Iwasaki, Nanba, Kimura, Hayashi: "Reactivation of persistent Epstein-Barr virus (EBV) causes secretion of thyrotropin receptor antibodies (TRAbs) in EBV-infected B lymphocytes with TRAbs on their surface." dans: Autoimmunity, Vol. 48, Issue 5, pp. 328-35, (2015) (PubMed).

Pessina, Castillo, Sartore, Borrego, Meikle: "Semiquantitative immunohistochemical marker staining and localization in canine thyroid carcinoma and normal thyroid gland." dans: Veterinary and comparative oncology, (2014) (PubMed).

Nishihara, Chen, Higashiyama, Mizutori-Sasai, Ito, Kubota, Amino, Miyauchi, Rapoport: "Subclinical nonautoimmune hyperthyroidism in a family segregates with a thyrotropin receptor mutation with weakly increased constitutive activity." dans: Thyroid : official journal of the American Thyroid Association, Vol. 20, Issue 11, pp. 1307-14, (2010) (PubMed).

Iizuka, Endo, Tsubochi, Nokubi, Matsuura, Sohara: "[Massive hemoptysis due to traction bronchiectasis caused by thoracic radiotherapy 23 years earlier]" dans: Kyobu geka. The Japanese journal of thoracic surgery, Vol. 61, Issue 3, pp. 226-9, (2008) (PubMed).

Neumann, Krause, Claus, Paschke: "Structural determinants for g protein activation and selectivity in the second intracellular loop of the thyrotropin receptor." dans: Endocrinology, Vol. 146, Issue 1, pp. 477-85, (2004) (PubMed).

Suh, Song, Kim, Kim, Chung, Hwang, Kim, Hwang, Chung, Han, Cho, Ro, Shong et al.: "Regulation of the phosphatidylinositol 3-kinase, Akt/protein kinase B, FRAP/mammalian target of rapamycin, and ribosomal S6 kinase 1 signaling pathways by thyroid-stimulating hormone (TSH) and ..." dans: The Journal of biological chemistry, Vol. 278, Issue 24, pp. 21960-71, (2003) (PubMed).

Chazenbalk, Pichurin, Chen, Latrofa, Johnstone, McLachlan, Rapoport: "Thyroid-stimulating autoantibodies in Graves disease preferentially recognize the free A subunit, not the thyrotropin holoreceptor." dans: The Journal of clinical investigation, Vol. 110, Issue 2, pp. 209-17, (2002) (PubMed).

Akamizu, Ikuyama, Saji, Kosugi, Kozak, McBride, Kohn: "Cloning, chromosomal assignment, and regulation of the rat thyrotropin receptor: expression of the gene is regulated by thyrotropin, agents that increase cAMP levels, and thyroid autoantibodies." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 87, Issue 15, pp. 5677-81, (1990) (PubMed).

Synonymes et noms alternatifs relatifs à TSH receptor

thyroid stimulating hormone receptor (tshr), thyroid stimulating hormone receptor (TSHR), thyroid stimulating hormone receptor (Tshr), AI481368, CHNG1, hTSHR-I, hypothroid, hyt, LGR3, pet, TSH-R, TSHRA

Protein level used designations for TSH receptor

  • TSH receptor
  • thyroid-stimulating hormone receptor
  • thyrotropin receptor
  • seven transmembrane helix receptor
  • thyrotropin receptor-I, hTSHR-I
  • TSH-R
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