TUBA1A Produits
(Tubulin, alpha 1a (Tuba1a))
Catégories
Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulins. The genes encoding these microtubule constituents belong to the tubulin superfamily, which is composed of six distinct families. Genes from the alpha, beta and gamma tubulin families are found in all eukaryotes. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes, which are highly conserved among species. This gene encodes alpha tubulin and is highly similar to the mouse and rat Tuba1 genes. Northern blotting studies have shown that the gene expression is predominantly found in morphologically differentiated neurologic cells. This gene is one of three alpha-tubulin genes in a cluster on chromosome 12q. Mutations in this gene cause lissencephaly type 3 (LIS3) - a neurological condition characterized by microcephaly, mental retardation, and early-onset epilepsy and caused by defective neuronal migration. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2012].
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Catégories TUBA1A en vedette
TUBA1A Anticorps
High quality antibodies with extensive validation data.
TUBA1A Kits ELISA
Reliable ELISA kits for a wide range of species.
TUBA1A Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
TUBA1A recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IF, IHC (p), ICC
Validations
- (1)
- (7)
N° du produit
ABIN2856707
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
ELISA, WB, IHC, IF, IP, FACS
Validations
- (6)
N° du produit
ABIN7127861
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
ELISA, WB, IF
Validations
- (1)
- (4)
N° du produit
ABIN521658
Quantité
100 μg
Fiche technique
Fiche technique
TUBA1A recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6960236
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Monkey
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN6200875
Quantité
96 tests
Fiche technique
Fiche technique
TUBA1A recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN7125523
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1324098
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1324100
Quantité
10 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits TUBA1A
: "Role of estrogen receptors and Src signaling in mechanisms of bone metastasis by estrogen receptor positive breast cancers." dans: Journal of translational medicine, Vol. 15, Issue 1, pp. 97, (2018) (PubMed).: "Sequences in Linker-1 domain of the multidrug resistance associated protein (MRP1 or ABCC1) bind to tubulin and their binding is modulated by phosphorylation." dans: Biochemical and biophysical research communications, Vol. 482, Issue 4, pp. 1001-1006, (2017) (PubMed).
: "Modulation of Wnt signaling is essential for the differentiation of ciliated epithelial cells in human airways." dans: FEBS letters, Vol. 591, Issue 21, pp. 3493-3506, (2017) (PubMed).
: "Germline CBL mutations cause developmental abnormalities and predispose to juvenile myelomonocytic leukemia. ..." dans: Nature genetics, Vol. 42, Issue 9, pp. 794-800, (2010) (PubMed).
: "Microtubule regulation in mitosis: tubulin phosphorylation by the cyclin-dependent kinase Cdk1." dans: Molecular biology of the cell, Vol. 17, Issue 3, pp. 1041-50, (2006) (PubMed).
: "Post-translational modifications regulate microtubule function." dans: Nature reviews. Molecular cell biology, Vol. 4, Issue 12, pp. 938-47, (2003) (PubMed).
Synonymes et noms alternatifs relatifs à TUBA1A
tubulin, alpha 1A (Tuba1a), tubulin alpha 1a (TUBA1A), tubulin, alpha 1a (TUBA1A), tubulin alpha-1B chain (LOC608147), tubulin alpha-1A chain (LOC100392817), tubulin alpha-3 chain-like (LOC425049), tubulin, alpha 1a (tuba1a), alpha-Tubulin at 84B (alphaTub84B), tubulin alpha-1A chain (LOC100051840), tubulin alpha-1A chain (LOC100340483), tubulin alpha-1A chain (LOC100726777), tubulin alpha 1a L homeolog (tuba1a.L), 1t, a-tub84B, a1t, alpha-Tub, alpha-tub, alpha-Tub84B, alpha-tub84B, alpha-tubulin, Alpha-Tubulin84B, alpha-tubulin 84B, alpha1, alpha1t, alpha1tub, alpha1tub84B, alpha84B, ALPHA 84C, alphaT, alphat-1, alphaTUB, alphaTub, alphatub, alphaTub1, alphaTub84, alphatub84, alphaTUB84B, alphatub84B, anon-EST:Liang-1.59, anon-EST:Liang-2.30, aTub84B, B-ALPHA-1, b-alpha-1, BEST:LD32507, CG1913, chr3R:2914276..2914416, clone 1.59, clone 2.30, DM1alpha, Dmel\CG1913, DTA1, l(3)84Bd, l(3)g3, LIS3, lis3, ms(3)nc33, nc33, T, Talpha1, TBA1_DROME, Tub, tub, Tub1C, Tub 84B, Tuba-1, Tuba1, TUBA1A, Tuba1a, tuba1a, tuba1a-a, tuba1a-b, Tuba2, TUBA3, tuba3, TUBA3D, TUBA3E, Tuba84B, tubA84B, Tubalpha1, tubalpha1, tubulin, wu:fb37a10Protein level used designations for TUBA1A
- alpha-tubulin 1
- tubulin alpha-1 chain
- tubulin alpha-1A chain
- tubulin, alpha 1
- hum-a-tub1
- hum-a-tub2
- tubulin B-alpha-1
- tubulin alpha-3 chain
- tubulin, alpha, brain-specific
- alpha-tubulin 3
- tubulin, alpha 3
- Talpha1 alpha-tubulin
- alpha-tubulin isotype M-alpha-1
- alpha-tubulin ubiquitous
- tubulin K-alpha-1
- tubulin alpha-1B chain
- tubulin alpha-ubiquitous chain
- tubulin, alpha 1a
- tubulin alpha-1A chain-like
- tubulin, alpha 3d
- tubulin, alpha 3e
- CG1913 gene product from transcript CG1913-RA
- CG1913-PA
- Tubulin-alpha1
- alpha tubulin
- alpha tubulin 84B
- alpha-Tubulin
- alpha-Tubulin 84B
- alpha-tubulin84B
- alpha1 tubulin
- alpha1-tubulin
- alphaT
- alphaTub84B-PA
- alphaTubulin 84B
- alphaTubulin84B
- alpha[[1]] tubulin
- alpha[[1]]-tubulin
- alphatubulin
- tubulin
- tubulin 1 alpha-chain
- tubulin 1alpha
- tubulin alpha1
- tubulin alpha1 promoter
- tubulin(alpha1)
- tubulin1alpha
- tubulin84B
- Alpha-tubulin 1
- Tubulin alpha-1 chain
- tubulin alpha 3
- Alpha-tubulin 2
- Alpha-tubulin II
- Tubulin alpha-2 chain
- alpha-tubulin II
- tubulin alpha 1a L homeolog
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