Tuberin Produits
(Tuberous Sclerosis 2 (TSC2))
Catégories
Mutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].
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Catégories Tuberin en vedette
Tuberin Anticorps
High quality antibodies with extensive validation data.
Tuberin Kits ELISA
Reliable ELISA kits for a wide range of species.
Tuberin recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IF, IHC (p)
Validations
- (5)
N° du produit
ABIN390324
Quantité
400 μL
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Application
WB, IHC (p)
Validations
- (7)
N° du produit
ABIN3043498
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Application
ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
- (1)
- (3)
N° du produit
ABIN701200
Quantité
100 μL
Fiche technique
Fiche technique
Tuberin recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6970922
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6970921
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Analytical Method
Qualitative Cell ELISA
Validations
N° du produit
ABIN1380275
Quantité
2 x 96 tests
Fiche technique
Fiche technique
Tuberin recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1323848
Quantité
10 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits Tuberin
: "Repression of TSC1/TSC2 mediated by MeCP2 regulates human embryo lung fibroblast cell differentiation and proliferation." dans: International journal of biological macromolecules, Vol. 96, pp. 578-588, (2017) (PubMed).: "PP2AC Level Determines Differential Programming of p38-TSC-mTOR Signaling and Therapeutic Response to p38-Targeted Therapy in Colorectal Cancer." dans: EBioMedicine, Vol. 2, Issue 12, pp. 1944-56, (2016) (PubMed).
: "Regulation of the mTOR signaling network in hibernating thirteen-lined ground squirrels." dans: The Journal of experimental biology, Vol. 215, Issue Pt 10, pp. 1720-7, (2012) (PubMed).
: "Phospho-?Np63?/Rpn13-dependent regulation of LKB1 degradation modulates autophagy in cancer cells." dans: Aging, Vol. 2, Issue 12, pp. 959-68, (2011) (PubMed).
: "Zebrafish Thsd7a is a neural protein required for angiogenic patterning during development." dans: Developmental dynamics : an official publication of the American Association of Anatomists, Vol. 240, Issue 6, pp. 1412-21, (2011) (PubMed).
: "Amplification of the angiogenic signal through the activation of the TSC/mTOR/HIF axis by the KSHV vGPCR in Kaposi's sarcoma." dans: PLoS ONE, Vol. 6, Issue 4, pp. e19103, (2011) (PubMed).
: "Mechanism of photooxidation of folic acid sensitized by unconjugated pterins." dans: Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology, Vol. 9, Issue 12, pp. 1604-12, (2010) (PubMed).
: "Tuberous sclerosis complex 2 (TSC2) regulates cell migration and polarity through activation of CDC42 and RAC1." dans: The Journal of biological chemistry, Vol. 285, Issue 32, pp. 24987-98, (2010) (PubMed).
: "A Large-scale genetic association study of esophageal adenocarcinoma risk." dans: Carcinogenesis, Vol. 31, Issue 7, pp. 1259-63, (2010) (PubMed).
: "Tuberous sclerosis complex activity is required to control neuronal stress responses in an mTOR-dependent manner." dans: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 29, Issue 18, pp. 5926-37, (2009) (PubMed).
Synonymes et noms alternatifs relatifs à Tuberin
TSC complex subunit 2 (TSC2), tuberin (LOC5569538), TSC complex subunit 2 (tsc2), hypothetical protein (PGTG_00159), tuberous sclerosis 2 (Tsc2), TSC complex subunit 2 (Tsc2), tuberous sclerosis 2 (TSC2), fc16b02, LAM, Nafld, Rc, Tcs2, TSC2, TSC4, tuberin, wu:fc16b02Protein level used designations for Tuberin
- tuberous sclerosis complex 2 (TSC2)
- tuberous sclerosis 2
- tuberin-like
- tuberin
- tuberous sclerosis 2 protein
- tuberous sclerosis 2 protein homolog
- renal carcinoma
- tuberous sclerosis 2 homolog protein
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