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Tumor Protein p73 Produits

(Tumor Protein P73 (TP73))
This gene encodes a member of the p53 family of transcription factors involved in cellular responses to stress and development. It maps to a region on chromosome 1p36 that is frequently deleted in neuroblastoma and other tumors, and thought to contain multiple tumor suppressor genes. The demonstration that this gene is monoallelically expressed (likely from the maternal allele), supports the notion that it is a candidate gene for neuroblastoma. Many transcript variants resulting from alternative splicing and/or use of alternate promoters have been found for this gene, but the biological validity and the full-length nature of some variants have not been determined. [provided by RefSeq, Feb 2011].

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Catégories Tumor Protein p73 en vedette

Tumor Protein p73 Anticorps

High quality antibodies with extensive validation data.

Tumor Protein p73 Kits ELISA

Reliable ELISA kits for a wide range of species.

Tumor Protein p73 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

Tumor Protein p73 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, ELISA, IHC (p)
Validations
  • (6)
N° du produit ABIN3181893
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IHC (p)
Validations
  • (6)
N° du produit ABIN3187855
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC
Validations
  • (11)
N° du produit ABIN6256817
Quantité 100 μL
Fiche technique Fiche technique

Tumor Protein p73 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Mouse, Rat
Analytical Method Qualitative DNA-Binding ELISA
Validations
N° du produit ABIN5648649
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human, Mouse
Analytical Method Qualitative Cell ELISA
Validations
N° du produit ABIN1380678
Quantité 2 x 96 tests
Fiche technique Fiche technique

Tumor Protein p73 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1323404
Quantité 25 μg
Fiche technique Fiche technique
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
N° du produit ABIN3085444
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
N° du produit ABIN3130163
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits Tumor Protein p73

Cam, Charan, Welker, Dravid, Studebaker, Leonard, Pierson, Nakano, Beattie, Hwang, Kambhampati, Nazarian, Finlay, Cam: "ΔNp73/ETS2 complex drives glioblastoma pathogenesis- targeting downstream mediators by rebastinib prolongs survival in preclinical models of glioblastoma." dans: Neuro-oncology, (2019) (PubMed).

Liu, Yang, Jing, Ren, Wei, Zhang, Zhang, Duan, Zhou, Sun: "Silica nanoparticle exposure inducing granulosa cell apoptosis and follicular atresia in female Balb/c mice." dans: Environmental science and pollution research international, Vol. 25, Issue 4, pp. 3423-3434, (2018) (PubMed).

Makino, Gutmann, Kosnopfel, Niessner, Forschner, Garbe, Sinnberg, Schittek: "Melanoma cells resistant towards MAPK inhibitors exhibit reduced TAp73 expression mediating enhanced sensitivity to platinum-based drugs." dans: Cell death & disease, Vol. 9, Issue 9, pp. 930, (2018) (PubMed).

Kumar, Talluri, Pal, Yuan, Lu, Nanjappa, Samur, Munshi, Shammas: "Role of apurinic/apyrimidinic nucleases in the regulation of homologous recombination in myeloma: mechanisms and translational significance." dans: Blood cancer journal, Vol. 8, Issue 10, pp. 92, (2018) (PubMed).

Yang, Yang, Tang, Zhang, Zhu, Wang, Wang, Ma: "Inhibition of DNA‑PK activity sensitizes A549 cells to X‑ray irradiation by inducing the ATM‑dependent DNA damage response." dans: Molecular medicine reports, Vol. 17, Issue 6, pp. 7545-7552, (2018) (PubMed).

Papaspyropoulos, Bradley, Thapa, Leung, Toskas, Koennig, Pefani, Raso, Grou, Hamilton, Vlahov, Grawenda, Haider, Chauhan, Buti, Kanapin, Lu, Buffa, Dianov, von Kriegsheim, Matallanas, Samsonova et al.: "RASSF1A uncouples Wnt from Hippo signalling and promotes YAP mediated differentiation via p73. ..." dans: Nature communications, Vol. 9, Issue 1, pp. 424, (2018) (PubMed).

González, De la Rosa, Rufini, Rodríguez-Hernández, Navarro-Villarán, Marchal, Pereira, De la Mata, Müller-Schilling, Pascasio-Acevedo, Ferrer-Ríos, Gómez-Bravo, Padillo, Muntané: "Role of p63 and p73 isoforms on the cell death in patients with hepatocellular carcinoma submitted to orthotopic liver transplantation." dans: PLoS ONE, Vol. 12, Issue 3, pp. e0174326, (2017) (PubMed).

Lee, Pelletier: "Dependence of p53-deficient cells on the DHX9 DExH-box helicase." dans: Oncotarget, Vol. 8, Issue 19, pp. 30908-30921, (2017) (PubMed).

Ng, Chan, Chai, Tong, Guan, Lee, Yuan, Xie, Lee, Dusetti, Carrier, Ma: "TP53INP1 Downregulation Activates a p73-Dependent DUSP10/ERK Signaling Pathway to Promote Metastasis of Hepatocellular Carcinoma." dans: Cancer research, Vol. 77, Issue 17, pp. 4602-4612, (2017) (PubMed).

Prabhu, Hong, Allen, Zhang, Lulla, Dicker, El-Deiry: "Small-Molecule Prodigiosin Restores p53 Tumor Suppressor Activity in Chemoresistant Colorectal Cancer Stem Cells via c-Jun-Mediated ΔNp73 Inhibition and p73 Activation." dans: Cancer research, Vol. 76, Issue 7, pp. 1989-99, (2016) (PubMed).

Synonymes et noms alternatifs relatifs à Tumor Protein p73

tumor protein p73 (TP73), tumor protein p73 (Tp73), tumor protein p73 (tp73), transformation related protein 73 (Trp73), P73, p73, TAp73, TP73, tp73, Tp73, Trp73, zp73theta

Protein level used designations for Tumor Protein p73

  • transformation related protein 73
  • tumor protein p73
  • tumor protein p73-like
  • p53-like transcription factor
  • p53-related protein
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