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UBA2 Produits

(SUMO1 Activating Enzyme Subunit 2 (UBA2))

Catégories

Posttranslational modification of proteins by the addition of the small protein SUMO (see SUMO1\; MIM 601912), or sumoylation, regulates protein structure and intracellular localization. SAE1 (MIM 613294) and UBA2 form a heterodimer that functions as a SUMO-activating enzyme for the sumoylation of proteins (Okuma et al., 1999 [PubMed 9920803]).[supplied by OMIM, Mar 2010].

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Catégories UBA2 en vedette

UBA2 Anticorps

High quality antibodies with extensive validation data.

UBA2 Kits ELISA

Reliable ELISA kits for a wide range of species.

UBA2 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

UBA2 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC
Validations
  • (6)
N° du produit ABIN5692937
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC (p)
Validations
  • (5)
N° du produit ABIN5708279
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC
Validations
  • (3)
  • (2)
N° du produit ABIN1944808
Quantité 100 μg
Fiche technique Fiche technique

UBA2 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Qualitative Cell ELISA
Validations
N° du produit ABIN1381576
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method
Validations
N° du produit ABIN421748
Quantité 96 tests
Fiche technique Fiche technique

UBA2 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1324292
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Baculovirus infected Insect Cells
Validations
  • (1)
N° du produit ABIN6387816
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7422214
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits UBA2

Sidik, Salsman, Dellaire, Rohde: "Shigella infection interferes with SUMOylation and increases PML-NB number." dans: PLoS ONE, Vol. 10, Issue 4, pp. e0122585, (2015) (PubMed).

Kho, Lee, Jeong, Oh, Gorski, Fish, Sanchez, DeVita, Christensen, Dahl, Hajjar: "Small-molecule activation of SERCA2a SUMOylation for the treatment of heart failure." dans: Nature communications, Vol. 6, pp. 7229, (2015) (PubMed).

Kanemaru, Saitoh: "High-yield expression of mouse Aos1-Uba2-fusion SUMO-activating enzyme, mAU, in a baculovirus-insect cell system." dans: Bioscience, biotechnology, and biochemistry, Vol. 77, Issue 7, pp. 1575-8, (2013) (PubMed).

Pal, Santos, Rosas, Ortiz-Guzman, Rosas-Acosta: "Influenza A virus interacts extensively with the cellular SUMOylation system during infection." dans: Virus research, Vol. 158, Issue 1-2, pp. 12-27, (2011) (PubMed).

La Salle, Sun, Zhang, Matunis, Handel: "Developmental control of sumoylation pathway proteins in mouse male germ cells." dans: Developmental biology, Vol. 321, Issue 1, pp. 227-37, (2008) (PubMed).

Rosendorff, Sakakibara, Lu, Kieff, Xuan, DiBacco, Shi, Shi, Gill: "NXP-2 association with SUMO-2 depends on lysines required for transcriptional repression." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, Issue 14, pp. 5308-13, (2006) (PubMed).

Wiemann, Weil, Wellenreuther, Gassenhuber, Glassl, Ansorge, Böcher, Blöcker, Bauersachs, Blum, Lauber, Düsterhöft, Beyer, Köhrer, Strack, Mewes, Ottenwälder, Obermaier, Tampe, Heubner, Wambutt, Korn et al.: "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. ..." dans: Genome research, Vol. 11, Issue 3, pp. 422-35, (2001) (PubMed).

Okuma, Honda, Ichikawa, Tsumagari, Yasuda: "In vitro SUMO-1 modification requires two enzymatic steps, E1 and E2." dans: Biochemical and biophysical research communications, Vol. 254, Issue 3, pp. 693-8, (1999) (PubMed).

Gong, Li, Millas, Yeh: "Molecular cloning and characterization of human AOS1 and UBA2, components of the sentrin-activating enzyme complex." dans: FEBS letters, Vol. 448, Issue 1, pp. 185-9, (1999) (PubMed).

Desterro, Rodriguez, Kemp, Hay: "Identification of the enzyme required for activation of the small ubiquitin-like protein SUMO-1." dans: The Journal of biological chemistry, Vol. 274, Issue 15, pp. 10618-24, (1999) (PubMed).

Synonymes et noms alternatifs relatifs à UBA2

SUMO1 activating enzyme subunit 2 (MICPUN_63834), SUMO1 activating enzyme subunit 2 (MICPUCDRAFT_36729), SUMO-activating enzyme 2 (SAE2), ubiquitin like modifier activating enzyme 2 (UBA2), ubiquitin-like modifier activating enzyme 2 (Uba2), ubiquitin like modifier activating enzyme 2 L homeolog (uba2.L), ubiquitin-like modifier activating enzyme 2 (uba2), AA986091, ARX, Arx, ATSAE2, EMB2764, EMBRYO DEFECTIVE 2764, F3K23.23, F3K23_23, SAE2, Sae2, sae2, sae2-B, sae2b, SUMO-ACTIVATING ENZYME 2, SUMO-activating enzyme 2, UBA1, uba2-a, uba2-b, Ubl1a2, Uble1b, uble1b, uble1b-B, wu:fi17g06, zgc:66354

Protein level used designations for UBA2

  • SUMO1 activating enzyme subunit 2
  • SUMO-1 activating enzyme subunit 2
  • SUMO-activating enzyme subunit 2
  • UBA2, ubiquitin-activating enzyme E1 homolog
  • anthracycline-associated resistance ARX
  • ubiquitin-like 1-activating enzyme E1B
  • Sumo-1 activating enzyme subunit 2
  • ubiquitin-like 1 (sentrin) activating enzyme E1B
  • ubiquitin-like 1 (sentrin) activating enzyme subunit 2
  • SUMO-activating enzyme subunit 2-A
  • SUMO-activating enzyme subunit 2-B
  • ubiquitin-like 1-activating enzyme E1B-A
  • ubiquitin-like 1-activating enzyme E1B-B
  • SUMO1 activating enzyme subunit 2b
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