Tel:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@anticorps-enligne.fr

ube3a Produits

(Ubiquitin Protein Ligase E3A (ube3a))

Catégories

This gene encodes an E3 ubiquitin-protein ligase, part of the ubiquitin protein degradation system. This imprinted gene is maternally expressed in brain and biallelically expressed in other tissues. Maternally inherited deletion of this gene causes Angelman Syndrome, characterized by severe motor and intellectual retardation, ataxia, hypotonia, epilepsy, absence of speech, and characteristic facies. The protein also interacts with the E6 protein of human papillomavirus types 16 and 18, resulting in ubiquitination and proteolysis of tumor protein p53. Alternative splicing of this gene results in three transcript variants encoding three isoforms with different N-termini. Additional transcript variants have been described, but their full length nature has not been determined. [provided by RefSeq, Jul 2008].

antibodies-online.com est synonyme de produits de recherche de haute qualité. Cherchez, trouvez et commandez des outils avec des données de validation étendues, des images, des références. Notre service clientèle scientifique est toujours à votre disposition si vous avez des questions sur la sélection ou l'application de nos produits.

Catégories ube3a en vedette

ube3a Anticorps

High quality antibodies with extensive validation data.

ube3a Kits ELISA

Reliable ELISA kits for a wide range of species.

ube3a Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

ube3a recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, ELISA, IF, IHC (p)
Validations
  • (1)
  • (6)
N° du produit ABIN563326
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Application IHC, IF
Validations
  • (11)
N° du produit ABIN7076105
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IF, IHC (p), FACS
Validations
  • (1)
  • (4)
N° du produit ABIN388925
Quantité 400 μL
Fiche technique Fiche technique

ube3a recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6971042
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6960350
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN1572964
Quantité 96 tests
Fiche technique Fiche technique

ube3a recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1324426
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1324424
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7393133
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits ube3a

Wang, Mitchell: "Cognition and Synaptic-Plasticity Related Changes in Aged Rats Supplemented with 8- and 10-Carbon Medium Chain Triglycerides." dans: PLoS ONE, Vol. 11, Issue 8, pp. e0160159, (2017) (PubMed).

Valluy, Bicker, Aksoy-Aksel, Lackinger, Sumer, Fiore, Wüst, Seffer, Metge, Dieterich, Wöhr, Schwarting, Schratt: "A coding-independent function of an alternative Ube3a transcript during neuronal development." dans: Nature neuroscience, Vol. 18, Issue 5, pp. 666-73, (2015) (PubMed).

Fletcher, Hill, Long, Gallagher, Shapiro, Rapp: "A fine balance: Regulation of hippocampal Arc/Arg3.1 transcription, translation and degradation in a rat model of normal cognitive aging." dans: Neurobiology of learning and memory, Vol. 115, pp. 58-67, (2014) (PubMed).

Tomaić, Ganti, Pim, Bauer, Blattner, Banks: "Interaction of HPV E6 oncoproteins with specific proteasomal subunits." dans: Virology, Vol. 446, Issue 1-2, pp. 389-96, (2013) (PubMed).

Wolyniec, Shortt, de Stanchina, Levav-Cohen, Alsheich-Bartok, Louria-Hayon, Corneille, Kumar, Woods, Opat, Johnstone, Scott, Segal, Pandolfi, Fox, Strasser, Jiang, Lowe, Haupt, Haupt: "E6AP ubiquitin ligase regulates PML-induced senescence in Myc-driven lymphomagenesis." dans: Blood, Vol. 120, Issue 4, pp. 822-32, (2012) (PubMed).

Meng, Person, Beaudet: "Ube3a-ATS is an atypical RNA polymerase II transcript that represses the paternal expression of Ube3a." dans: Human molecular genetics, Vol. 21, Issue 13, pp. 3001-12, (2012) (PubMed).

Daily, Smith, Weeber: "Spatial and temporal silencing of the human maternal UBE3A gene." dans: European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society, Vol. 16, Issue 6, pp. 587-91, (2012) (PubMed).

Daily, Nash, Jinwal, Golde, Rogers, Peters, Burdine, Dickey, Banko, Weeber: "Adeno-associated virus-mediated rescue of the cognitive defects in a mouse model for Angelman syndrome." dans: PLoS ONE, Vol. 6, Issue 12, pp. e27221, (2011) (PubMed).

Sato, Stryker: "Genomic imprinting of experience-dependent cortical plasticity by the ubiquitin ligase gene Ube3a." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 12, pp. 5611-6, (2010) (PubMed).

Ramamoorthy, Dhananjayan, Demayo, Nawaz: "Isoform-specific degradation of PR-B by E6-AP is critical for normal mammary gland development." dans: Molecular endocrinology (Baltimore, Md.), Vol. 24, Issue 11, pp. 2099-113, (2010) (PubMed).

Synonymes et noms alternatifs relatifs à ube3a

ubiquitin protein ligase E3A (UBE3A), ubiquitin-protein ligase E3A (ube3a), ubiquitin-protein ligase E3A (LOC100194730), ubiquitin protein ligase E3A (Ube3a), ubiquitin protein ligase E3A (ube3a), Ubiquitin protein ligase E3A (Ube3a), ubiquitin protein ligase E3A (human papilloma virus E6-associated protein, Angelman syndrome) S homeolog (ube3a.S), ubiquitin protein ligase E3A (human papilloma virus E6-associated protein, Angelman syndrome) (ube3a), ubiquitin protein ligase E3A (Eint_040430), 4732496B02, 5830462N02Rik, A130086L21Rik, ANCR, AS, As, CG6190, das, DDBDRAFT_0188760, DDBDRAFT_0302447, DDB_0188760, DDB_0302447, Dmel\\CG6190, Dube3a, dUBE3A, dube3A, dube3a, E6-AP, EPVE6AP, HPVE6A, Hpve6a, im:7140733, MGC69536, mKIAA4216, ube3a, UBE3A, UME3A, zgc:92173

Protein level used designations for ube3a

  • CTCL tumor antigen se37-2
  • E6AP ubiquitin-protein ligase
  • human papilloma virus E6-associated protein
  • human papillomavirus E6-associated protein
  • oncogenic protein-associated protein E6-AP
  • renal carcinoma antigen NY-REN-54
  • ubiquitin-protein ligase E3A
  • ubiquitin protein ligase E3A (human papilloma virus E6-associated protein, Angelman syndrome)
  • ubiquitin protein ligase E3A
  • E6-AP ubiquitin protein ligase
  • ubiquitin conjugating enzyme E3A
  • CG6190-PA
  • Ube3a-PA
  • drosophila angelman syndrome
  • angelman syndrome
  • ubiquitin-protein ligase E3A-like
Vous êtes ici:
Support technique