Ubiquilin 1 Produits
(Ubiquilin 1 (UBQLN1))
Catégories
This gene encodes an ubiquitin-like protein (ubiquilin) that shares a high degree of similarity with related products in yeast, rat and frog. Ubiquilins contain an N-terminal ubiquitin-like domain and a C-terminal ubiquitin-associated domain. They physically associate with both proteasomes and ubiquitin ligases, and thus are thought to functionally link the ubiquitination machinery to the proteasome to affect in vivo protein degradation. This ubiquilin has also been shown to modulate accumulation of presenilin proteins, and it is found in lesions associated with Alzheimer's and Parkinson's disease. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
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Catégories Ubiquilin 1 en vedette
Ubiquilin 1 Anticorps
High quality antibodies with extensive validation data.
Ubiquilin 1 Kits ELISA
Reliable ELISA kits for a wide range of species.
Ubiquilin 1 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
Ubiquilin 1 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human, Mouse
Application
WB, IHC (p), IF
Validations
- (3)
- (3)
N° du produit
ABIN388966
Quantité
400 μL
Fiche technique
Fiche technique
Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Monkey, Rabbit, Sheep
Application
WB, IHC, IHC (p)
Validations
- (4)
N° du produit
ABIN6741620
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human, Mouse
Application
WB, ELISA, IHC, IF
Validations
- (5)
N° du produit
ABIN3029415
Quantité
0.4 mL
Fiche technique
Fiche technique
Ubiquilin 1 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6971031
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN6208313
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Validations
N° du produit
ABIN1164827
Quantité
96 tests
Fiche technique
Fiche technique
Ubiquilin 1 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1324458
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
N° du produit
ABIN2734885
Quantité
20 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
N° du produit
ABIN2734886
Quantité
20 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits Ubiquilin 1
: "APP modulates KCC2 expression and function in hippocampal GABAergic inhibition." dans: eLife, Vol. 6, (2018) (PubMed).: "MiR-200c inhibits autophagy and enhances radiosensitivity in breast cancer cells by targeting UBQLN1." dans: International journal of cancer. Journal international du cancer, Vol. 136, Issue 5, pp. 1003-12, (2014) (PubMed).
: "Tau pathology in frontotemporal lobar degeneration with C9ORF72 hexanucleotide repeat expansion." dans: Acta neuropathologica, Vol. 125, Issue 2, pp. 289-302, (2013) (PubMed).
: "UBQLN1 interacts with SPEM1 and participates in spermiogenesis." dans: Molecular and cellular endocrinology, Vol. 327, Issue 1-2, pp. 89-97, (2010) (PubMed).
: "Activation of CD47 receptors causes proliferation of human astrocytoma but not normal astrocytes via an Akt-dependent pathway." dans: Glia, Vol. 59, Issue 2, pp. 308-19, (2010) (PubMed).
: "Overexpression of ubiquilin decreases ubiquitination and degradation of presenilin proteins." dans: Journal of Alzheimer's disease : JAD, Vol. 6, Issue 1, pp. 79-92, (2004) (PubMed).
: "Interaction with a ubiquitin-like protein enhances the ubiquitination and degradation of hepatitis C virus RNA-dependent RNA polymerase." dans: Journal of virology, Vol. 77, Issue 7, pp. 4149-59, (2003) (PubMed).
: "The hPLIC proteins may provide a link between the ubiquitination machinery and the proteasome." dans: Molecular cell, Vol. 6, Issue 2, pp. 409-19, (2000) (PubMed).
: "Identification of ubiquilin, a novel presenilin interactor that increases presenilin protein accumulation." dans: The Journal of cell biology, Vol. 151, Issue 4, pp. 847-62, (2000) (PubMed).
Synonymes et noms alternatifs relatifs à Ubiquilin 1
ubiquilin 1 (UBQLN1), ubiquilin 1 (Ubqln1), 1110046H03Rik, 1810030E05Rik, AU019746, C77538, D13Ertd372e, DA41, Da41, DSK2, Dsk2, PLIC-1, Plic-1, Plic1, UBQLN1, UBQN, XDRP1, Xdrp1Protein level used designations for Ubiquilin 1
- ubiquilin-1
- ubiquilin 1
- ubiquilin-1-like
- hPLIC-1
- protein linking IAP with cytoskeleton 1
- PLIC-1
Avez-vous cherché autre chose?
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- UBE3B
- ube3a
- UBE2Z
- UBE2W
- UBE2V2
- UBE2V1
- UBE2U
- Ube2t
- UBE2S.2
- UBE2R2
- UBE2QL1
- UBE2Q2
- Ubiquilin 2
- Ubiquilin 3
- Ubiquinol-Cytochrome C Reductase Complex Assembly Factor 3
- Ubiquinol-Cytochrome C Reductase Complex Chaperone
- Ubiquinol-Cytochrome C Reductase Core Protein II
- Ubiquitin
- Ubiquitin +1
- Ubiquitin 11
- Ubiquitin Associated Protein 1
- Ubiquitin B
- Ubiquitin Specific Peptidase 12
- Ubiquitin-Conjugating Enzyme E2D 3
- Ubiquitin-Conjugating Enzyme E2E 3
- Ubiquitin-Conjugating Enzyme E2G 2
- Ubiquitin-Conjugating Enzyme E2I
- Ubiquitin-Conjugating Enzyme E2K
- Ubiquitin-Conjugating Enzyme E2N
- Ubiquitin-Conjugating Enzyme E2S
- UBL3
- UBL4A
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