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Ubiquitin Produits

(Ubiquitin)
Ubiquitin exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys in protein degradation via the proteasome. Linear polymer chains formed via attachment by the initiator Met lead to cell signaling. Ubiquitin is usually conjugated to Lys residues of target proteins, however, in rare cases, conjugation to Cys or Ser residues has been observed. When polyubiquitin is free (unanchored-polyubiquitin), it also has distinct roles, such as in activation of protein kinases, and in signaling (By similarity).

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Catégories Ubiquitin en vedette

Ubiquitin Anticorps

High quality antibodies with extensive validation data.

Ubiquitin Kits ELISA

Reliable ELISA kits for a wide range of species.

Ubiquitin Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

Ubiquitin recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Cow
Application WB, IHC, IF, ICC, IP
Validations
  • (2)
  • (6)
N° du produit ABIN361831
Quantité 200 μL
Fiche technique Fiche technique
Reactivity Cow, Dog, Horse, Human, Mouse, Pig, Rabbit, Rat
Application WB, IHC, ICC, IP
Validations
  • (7)
N° du produit ABIN7443803
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human, Rat
Application WB, IHC, ICC, IP
Validations
  • (9)
N° du produit ABIN7428593
Quantité 100 μL
Fiche technique Fiche technique

Ubiquitin recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
N° du produit ABIN6962238
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Cow, Dog, Horse, Human, Mouse, Pig, Rabbit, Rat
Analytical Method Quantitative Competition ELISA
Validations
  • (1)
N° du produit ABIN6960339
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN5526834
Quantité 96 tests
Fiche technique Fiche technique

Ubiquitin recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN7125573
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN934908
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7505806
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits Ubiquitin

Aubi, Prestegård, Jung-Kc, Shi, Ying, Grindheim, Scherer, Ulvik, McCann, Spriet, Thöny, Martinez: "The Pah-R261Q mouse reveals oxidative stress associated with amyloid-like hepatic aggregation of mutant phenylalanine hydroxylase." dans: Nature communications, Vol. 12, Issue 1, pp. 2073, (2021) (PubMed).

Ji, Yao, Zhao, Zhai, Weng, He: "Extracellular ubiquitin levels are increased in coronary heart disease and associated with the severity of the disease." dans: Scandinavian journal of clinical and laboratory investigation, Vol. 80, Issue 3, pp. 256-264, (2020) (PubMed).

Aalto, Mohan, Schwintzer, Kupka, Kietz, Walczak, Broemer, Meinander: "M1-linked ubiquitination by LUBEL is required for inflammatory responses to oral infection in Drosophila." dans: Cell death and differentiation, Vol. 26, Issue 5, pp. 860-876, (2019) (PubMed).

Gladkova, Maslen, Skehel, Komander: "Mechanism of parkin activation by PINK1." dans: Nature, Vol. 559, Issue 7714, pp. 410-414, (2019) (PubMed).

Sn, Pandurangi, Murumalla, Dj, Garimella, Acharya, Rai, Paul, Yarreiphang, Pillai, Giridharan, Clement, Alladi, Saiyed, Manjithaya: "Small molecule modulator of aggrephagy regulates neuroinflammation to curb pathogenesis of neurodegeneration." dans: EBioMedicine, Vol. 50, pp. 260-273, (2019) (PubMed).

Nombela, Requena-Platek, Morales-Lange, Chico, Puente-Marin, Ciordia, Mena, Coll, Perez, Mercado, Ortega-Villaizan: "Rainbow Trout Red Blood Cells Exposed to Viral Hemorrhagic Septicemia Virus Up-Regulate Antigen-Processing Mechanisms and MHC I&II, CD86, and CD83 Antigen-presenting Cell Markers." dans: Cells, Vol. 8, Issue 5, (2019) (PubMed).

Gogoi, Ravikumar, Dixit, Chakravortty: "Salmonella escapes K63 ubiquitination mediated MHC II endosomal proteolysis via modulation of endosomal acidification in dendritic cells." dans: Pathogens and disease, (2018) (PubMed).

Yang, Liu, Yao, Jiang, Wang, Yang, Sun, Miao, Wang, Huang, Wang, Tang, Rayner, Britt, McVoy, Luo, Zhao: "WDR5 Facilitates Human Cytomegalovirus Replication by Promoting Capsid Nuclear Egress." dans: Journal of virology, Vol. 92, Issue 9, (2018) (PubMed).

Michel, Swatek, Hospenthal, Komander: "Ubiquitin Linkage-Specific Affimers Reveal Insights into K6-Linked Ubiquitin Signaling." dans: Molecular cell, Vol. 68, Issue 1, pp. 233-246.e5, (2017) (PubMed).

Gersch, Gladkova, Schubert, Michel, Maslen, Komander: "Mechanism and regulation of the Lys6-selective deubiquitinase USP30." dans: Nature structural & molecular biology, Vol. 24, Issue 11, pp. 920-930, (2017) (PubMed).

Synonymes et noms alternatifs relatifs à Ubiquitin

Ubiquitin-63E (Ubi-p63E), Ubiquitin-5E (Ubi-p5E), transmembrane and ubiquitin-like domain containing 2 (tmub2), polyubiquitin (LOC100194618), Putative ubiquitin family protein (pco110026), ubiquitin (LOC100135798), ubiquitin B (UBB), UBiQuitin (ubq-1), Ubiquitin (LOC100190766), CG11624, CG18282, CG32744, CR32744, Dmel\\CG11624, Dmel\\CG32744, DmUb, DmUbi-p5E, DmUbi-p63E, LOC100194618, LOC100282068, si:busm1-180g5.5, si:dz180g5.5, Ub, ubi, Ubi-p, Ubi-P63e, ubi-p63E, Ubi63E, ubi63E, Ubi63p, Ubip, Ubiq, UBIQ, ubiquitin, Ubiquitin, Ubp

Protein level used designations for Ubiquitin

  • CG11624-PA
  • CG11624-PB
  • CG11624-PC
  • CG11624-PD
  • Ubi-p63E-PA
  • Ubi-p63E-PB
  • Ubi-p63E-PC
  • Ubi-p63E-PD
  • Ubiquitin-polymeric
  • polyubiquitin
  • ubiquitin
  • CG32744-PA
  • Ubi-p5E-PA
  • transmembrane and ubiquitin-like domain-containing protein 2
  • polyubiquitin containing 7 ubiquitin monomers
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