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Ubiquitin B Produits

(Ubiquitin B (UBB))
This gene encodes ubiquitin, one of the most conserved proteins known. Ubiquitin is required for ATP-dependent, nonlysosomal intracellular protein degradation of abnormal proteins and normal proteins with a rapid turnover. Ubiquitin is covalently bound to proteins to be degraded, and presumably labels these proteins for degradation. Ubiquitin also binds to histone H2A in actively transcribed regions but does not cause histone H2A degradation, suggesting that ubiquitin is also involved in regulation of gene expression. This gene consists of three direct repeats of the ubiquitin coding sequence with no spacer sequence. Consequently, the protein is expressed as a polyubiquitin precursor with a final amino acid after the last repeat. Aberrant form of this protein has been noticed in patients with Alzheimer's and Down syndrome. [provided by RefSeq, Jul 2008].

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Catégories Ubiquitin B en vedette

Ubiquitin B Anticorps

High quality antibodies with extensive validation data.

Ubiquitin B Kits ELISA

Reliable ELISA kits for a wide range of species.

Ubiquitin B Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

Ubiquitin B recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC, FACS, IF, StM
Validations
  • (6)
N° du produit ABIN6940844
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, FACS
Validations
  • (2)
  • (4)
N° du produit ABIN969573
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC, ELISA, StM, Coat
Validations
  • (5)
N° du produit ABIN6940845
Quantité 100 μg
Fiche technique Fiche technique

Ubiquitin B recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6971035
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rat
Analytical Method
Validations
  • (1)
N° du produit ABIN579427
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method
Validations
N° du produit ABIN456733
Quantité 96 tests
Fiche technique Fiche technique

Ubiquitin B recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1324322
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN2115459
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7318921
Quantité 50 μg
Fiche technique Fiche technique

Dernières publications sur nos produits Ubiquitin B

Yang, Liu, Yao, Jiang, Wang, Yang, Sun, Miao, Wang, Huang, Wang, Tang, Rayner, Britt, McVoy, Luo, Zhao: "WDR5 Facilitates Human Cytomegalovirus Replication by Promoting Capsid Nuclear Egress." dans: Journal of virology, Vol. 92, Issue 9, (2018) (PubMed).

Zhang, Wang, Zhong, Luo, Shang, Liu, Chen, Fang, Xiao: "Ubiquitin-specific Protease 15 Negatively Regulates Virus-induced Type I Interferon Signaling via Catalytically-dependent and -independent Mechanisms." dans: Scientific reports, Vol. 5, pp. 11220, (2016) (PubMed).

Cheng, Wang, Jiang, Wang, Xin, Liu, Jia, Song, Zhu: "A novel ubiquitin-protein ligase E3 functions as a modulator of immune response against lipopolysaccharide in Pacific oyster, Crassostrea gigas." dans: Developmental and comparative immunology, Vol. 60, pp. 180-90, (2016) (PubMed).

Li, Liu, Yang, Fu, Zhao, Shen, Miao, Rayner, Chavanas, Zhu, Britt, Tang, McVoy, Luo: "Human Cytomegalovirus Infection Dysregulates the Localization and Stability of NICD1 and Jag1 in Neural Progenitor Cells." dans: Journal of virology, Vol. 89, Issue 13, pp. 6792-804, (2015) (PubMed).

Zhong, Wang, Fang, Zhang, Luo, Shang, Ouyang, Ouyang, Chen, Xiao: "Ubiquitin-specific proteases 25 negatively regulates virus-induced type I interferon signaling." dans: PLoS ONE, Vol. 8, Issue 11, pp. e80976, (2013) (PubMed).

Di Filippo, Capuano, Rinaldi, Luongo, Lettieri, Rossi, DAmico: "Intraperitoneal oxygen/ozone treatment decreases the formation of experimental postsurgical peritoneal adhesions and the levels/activity of the local ubiquitin-proteasome system." dans: Mediators of inflammation, Vol. 2011, pp. 606718, (2012) (PubMed).

Choudhary, Kumar, Gnad, Nielsen, Rehman, Walther, Olsen, Mann: "Lysine acetylation targets protein complexes and co-regulates major cellular functions." dans: Science (New York, N.Y.), Vol. 325, Issue 5942, pp. 834-40, (2009) (PubMed).

Komander: "The emerging complexity of protein ubiquitination." dans: Biochemical Society transactions, Vol. 37, Issue Pt 5, pp. 937-53, (2009) (PubMed).

Vernes, Nicod, Elahi, Coventry, Kenny, Coupe, Bird, Davies, Fisher: "Functional genetic analysis of mutations implicated in a human speech and language disorder." dans: Human molecular genetics, Vol. 15, Issue 21, pp. 3154-67, (2006) (PubMed).

Synonymes et noms alternatifs relatifs à Ubiquitin B

ubiquitin B (UBB), ubiquitin B (Ubb), ubiquitin C (UBC), ubiquitin B (ubb), AL033289, im:6892314, Rps27a, si:ch211-202a12.3, Uba52, UBB, Ubb2, Ubc, UBC, ubc, Ubi-p63E, Ubiquitin, zgc:172187, zUBC

Protein level used designations for Ubiquitin B

  • polyubiquitin B
  • polyubiquitin-B
  • polyubiquitin
  • ubiquitin C
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