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UFD1L Produits

(Ubiquitin Fusion Degradation Protein 1 Homolog (UFD1L))

Catégories

The protein encoded by this gene forms a complex with two other proteins, nuclear protein localization-4 and valosin-containing protein, and this complex is necessary for the degradation of ubiquitinated proteins. In addition, this complex controls the disassembly of the mitotic spindle and the formation of a closed nuclear envelope after mitosis. Mutations in this gene have been associated with Catch 22 syndrome as well as cardiac and craniofacial defects. Alternative splicing results in multiple transcript variants encoding different isoforms. A related pseudogene has been identified on chromosome 18. [provided by RefSeq, Jun 2009].

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Catégories UFD1L en vedette

UFD1L Anticorps

High quality antibodies with extensive validation data.

UFD1L Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

UFD1L recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application IHC, ELISA, ICC
Validations
  • (6)
N° du produit ABIN5542400
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC, ELISA, ICC, FACS
Validations
  • (9)
N° du produit ABIN5542401
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human, Mouse
Application WB, IF, IHC (p), ICC
Validations
  • (6)
N° du produit ABIN2856688
Quantité 100 μL
Fiche technique Fiche technique

UFD1L recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN7125585
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1324547
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1324549
Quantité 10 μg
Fiche technique Fiche technique

Dernières publications sur nos produits UFD1L

Guo, Qi: "VCP cooperates with UBXD1 to degrade mitochondrial outer membrane protein MCL1 in model of Huntington's disease." dans: Biochimica et biophysica acta, Vol. 1863, Issue 2, pp. 552-559, (2016) (PubMed).

Nagahama, Suzuki, Hamada, Hatsuzawa, Tani, Yamamoto, Tagaya: "SVIP is a novel VCP/p97-interacting protein whose expression causes cell vacuolation." dans: Molecular biology of the cell, Vol. 14, Issue 1, pp. 262-73, (2003) (PubMed).

Meyer, Shorter, Seemann, Pappin, Warren: "A complex of mammalian ufd1 and npl4 links the AAA-ATPase, p97, to ubiquitin and nuclear transport pathways." dans: The EMBO journal, Vol. 19, Issue 10, pp. 2181-92, (2000) (PubMed).

Yamagishi, Garg, Matsuoka, Thomas, Srivastava: "A molecular pathway revealing a genetic basis for human cardiac and craniofacial defects." dans: Science (New York, N.Y.), Vol. 283, Issue 5405, pp. 1158-61, (1999) (PubMed).

Pizzuti, Novelli, Ratti, Amati, Mari, Calabrese, Nicolis, Silani, Marino, Scarlato, Ottolenghi, Dallapiccola: "UFD1L, a developmentally expressed ubiquitination gene, is deleted in CATCH 22 syndrome." dans: Human molecular genetics, Vol. 6, Issue 2, pp. 259-65, (1997) (PubMed).

Synonymes et noms alternatifs relatifs à UFD1L

ubiquitin recognition factor in ER associated degradation 1 (UFD1), ubiquitin recognition factor in ER-associated degradation 1 (Ufd1), ubiquitin recognition factor in ER associated degradation 1 (Ufd1), ubiquitin fusion degradation 1 like (yeast) (UFD1L), ubiquitin recognition factor in ER associated degradation 1 S homeolog (ufd1.S), ubiquitin recognition factor in ER associated degradation 1 (ufd1l), ubiquitin recognition factor in ER associated degradation 1 (ufd1), ubiquitin fusion degradation protein 1 homolog (EHI_125920), ubiquitin fusion degradation protein 1 homolog (LOC100166745), ubiquitin fusion degradation protein 1 homolog (LOC100635687), ubiquitin fusion degradation protein 1 homolog (LOC100648660), Ubiquitin Fusion Degradation (yeast UFD homolog) (ufd-1), UFD1, Ufd1, ufd1, Ufd1l, wu:fc55f04, zgc:92341

Protein level used designations for UFD1L

  • UB fusion protein 1
  • ubiquitin fusion degradation protein 1 homolog
  • ubiquitin fusion degradation 1-like protein
  • fc55f04
  • ubiquitin fusion degradation 1-like
  • ubiquitin fusion degradation 1 like (yeast)
  • ubiquitin fusion degradation 1 like
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