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UGT1A9 Produits

(UDP Glucuronosyltransferase 1 Family, Polypeptide A9 (UGT1A9))

Catégories

This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. The enzyme encoded by this gene is active on phenols. [provided by RefSeq, Jul 2008].

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Catégories UGT1A9 en vedette

UGT1A9 Anticorps

High quality antibodies with extensive validation data.

UGT1A9 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

UGT1A9 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC (p)
Validations
  • (2)
  • (3)
N° du produit ABIN527130
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC
Validations
  • (4)
N° du produit ABIN3022343
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application IF, IHC, ELISA
Validations
  • (3)
N° du produit ABIN7174631
Quantité 100 μg
Fiche technique Fiche technique

UGT1A9 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1324584
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1324582
Quantité 10 μg
Fiche technique Fiche technique

Dernières publications sur nos produits UGT1A9

Wang, Bian, Jin, Chen, Lin, Chen: "Association analysis of UGT1A genotype and haplotype with SN-38 glucuronidation in human livers." dans: Pharmacogenomics, Vol. 15, Issue 6, pp. 785-98, (2014) (PubMed).

Hardwick, Ferreira, More, Lake, Lu, Manautou, Slitt, Cherrington: "Altered UDP-glucuronosyltransferase and sulfotransferase expression and function during progressive stages of human nonalcoholic fatty liver disease." dans: Drug metabolism and disposition: the biological fate of chemicals, Vol. 41, Issue 3, pp. 554-61, (2013) (PubMed).

Oda, Nakajima, Hatakeyama, Fukami, Yokoi: "Preparation of a specific monoclonal antibody against human UDP-glucuronosyltransferase (UGT) 1A9 and evaluation of UGT1A9 protein levels in human tissues." dans: Drug metabolism and disposition: the biological fate of chemicals, Vol. 40, Issue 8, pp. 1620-7, (2012) (PubMed).

Izukawa, Nakajima, Fujiwara, Yamanaka, Fukami, Takamiya, Aoki, Ikushiro, Sakaki, Yokoi: "Quantitative analysis of UDP-glucuronosyltransferase (UGT) 1A and UGT2B expression levels in human livers." dans: Drug metabolism and disposition: the biological fate of chemicals, Vol. 37, Issue 8, pp. 1759-68, (2009) (PubMed).

Synonymes et noms alternatifs relatifs à UGT1A9

UDP glycosyltransferase 1 family, polypeptide A9 (UGT1A9), UDP glucuronosyltransferase 1 family, polypeptide A9 (UGT1A9), UDP glucuronosyltransferase family 1 member A9 (UGT1A9), UDP glucuronosyltransferase 1 family, polypeptide A9 (Ugt1a9), UDP glucuronosyltransferase family 1 member A9 (Ugt1a9), DKFZP469N0814, HLUGP4, LUGP4, mUGTBr/P, SHEUGT1A07, UDPGT, UDPGT 1-9, UGT-1I, UGT1-09, UGT1-9, UGT1.9, UGT1A9, Ugt1a10, Ugt1a11, Ugt1a12, UGT1AI, UGT1I, UGTP4

Protein level used designations for UGT1A9

  • UDP glycosyltransferase 1 family, polypeptide A9
  • UDP-glucuronosyltransferase 1-9
  • UDP-glucuronosyltransferase 1A9
  • UDP glucuronosyltransferase 1 family, polypeptide A9
  • UDP glycosyl transferase 1A9
  • UDP-glucuronosyltransferase 1-I
  • UDP glycosyltransferase 1 family polypeptide A12
  • UDP-glucuronosyltransferase 1-7
  • UDP glycosyltransferase 1 family polypeptide A10
  • UDP glycosyltransferase 1 family polypeptide A11
  • UDP glycosyltransferase 1 family, polypeptide A10
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