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UMPS Produits

(Uridine Monophosphate Synthetase (UMPS))

Catégories

This gene encodes a uridine 5'-monophosphate synthase. The encoded protein is a bifunctional enzyme that catalyzes the final two steps of the de novo pyrimidine biosynthetic pathway. The first reaction is carried out by the N-terminal enzyme orotate phosphoribosyltransferase which converts orotic acid to orotidine-5'-monophosphate. The terminal reaction is carried out by the C-terminal enzyme OMP decarboxylase which converts orotidine-5'-monophosphate to uridine monophosphate. Defects in this gene are the cause of hereditary orotic aciduria. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2010].

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Catégories UMPS en vedette

UMPS Anticorps

High quality antibodies with extensive validation data.

UMPS Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

UMPS recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique

Application WB, IHC
Validations
  • (1)
  • (6)
N° du produit ABIN2783243
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IF
Validations
  • (1)
  • (4)
N° du produit ABIN521259
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application ELISA, IHC, IF
Validations
  • (3)
N° du produit ABIN7175108
Quantité 100 μg
Fiche technique Fiche technique

UMPS recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1324639
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1324637
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
  • (1)
N° du produit ABIN2735007
Quantité 20 μg
Fiche technique Fiche technique

Dernières publications sur nos produits UMPS

Griffith, Mwenifumbo, Cheung, Paul, Pugh, Tang, Chittaranjan, Morin, Asano, Ally, Miao, Lee, Chan, Taylor, Severson, Hou, Griffith, Cheng, Novik, Moore, Luk, Owen, Brown, Morin, Gill, Tai, Marra: "Novel mRNA isoforms and mutations of uridine monophosphate synthetase and 5-fluorouracil resistance in colorectal cancer." dans: The pharmacogenomics journal, Vol. 13, Issue 2, pp. 148-58, (2013) (PubMed).

Bardeleben, Sharma, Reeve, Bassilian, Frost, Hoang, Shi, Lichtenstein: "Metabolomics identifies pyrimidine starvation as the mechanism of 5-aminoimidazole-4-carboxamide-1-β-riboside-induced apoptosis in multiple myeloma cells." dans: Molecular cancer therapeutics, Vol. 12, Issue 7, pp. 1310-21, (2013) (PubMed).

Koopman, Venderbosch, van Tinteren, Ligtenberg, Nagtegaal, Van Krieken, Punt: "Predictive and prognostic markers for the outcome of chemotherapy in advanced colorectal cancer, a retrospective analysis of the phase III randomised CAIRO study." dans: European journal of cancer (Oxford, England : 1990), Vol. 45, Issue 11, pp. 1999-2006, (2009) (PubMed).

Ishikawa, Kondo, Yamaguchi, Sakamoto, Fujisawa: "Effect of varicocelectomy on patients with unobstructive azoospermia and severe oligospermia." dans: BJU international, Vol. 101, Issue 2, pp. 216-8, (2008) (PubMed).

Synonymes et noms alternatifs relatifs à UMPS

Orotidine 5'-phosphate decarboxylase (umps-1), uridine monophosphate synthetase (umps), uridine monophosphate synthetase L homeolog (umps.L), uridine monophosphate synthetase (UMPS), uridine 5'-monophosphate synthase (LOC100556619), uridine monophosphate synthetase (Umps), 1700095D23Rik, AA408257, AL033308, BB164745, OPRT, UMPS, zgc:55702, zgc:55723

Protein level used designations for UMPS

  • Uridine MonoPhosphate Synthetase family member (umps-1)
  • uridine 5'-monophosphate synthase
  • uridine monophosphate synthetase
  • uridine monophosphate synthase
  • uridine monophosphate synthetase (orotate phosphoribosyl transferase and orotidine-5'-decarboxylase)
  • OMPdecase
  • OPRTase
  • UMP synthase
  • orotate phosphoribosyltransferase
  • orotidine 5'-phosphate decarboxylase
  • orotate phosphoribosyl transferase and orotidine-5'-decarboxylase
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