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UNC13D Produits

(Unc-13 Homolog D (UNC13D))

Catégories

This gene encodes an RGD-containing protein that binds to type I, II and IV collagens. The RGD motif is found in many extracellular matrix proteins modulating cell adhesion and serves as a ligand recognition sequence for several integrins. This protein plays a role in cell-collagen interactions and may be involved in endochondrial bone formation in cartilage. The protein is induced by transforming growth factor-beta and acts to inhibit cell adhesion. Mutations in this gene are associated with multiple types of corneal dystrophy. [provided by RefSeq, Jul 2008].

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Catégories UNC13D en vedette

UNC13D Anticorps

High quality antibodies with extensive validation data.

UNC13D Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

UNC13D recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, ELISA
Validations
  • (4)
N° du produit ABIN531286
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, IF, IHC (p), ICC
Validations
  • (3)
N° du produit ABIN2856569
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human, Mouse
Application WB, ELISA, IHC
Validations
  • (3)
N° du produit ABIN185677
Quantité 100 μg
Fiche technique Fiche technique

UNC13D recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN6219996
Quantité 96 tests
Fiche technique Fiche technique

UNC13D recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1324647
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
N° du produit ABIN3096260
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
N° du produit ABIN2735014
Quantité 20 μg
Fiche technique Fiche technique

Dernières publications sur nos produits UNC13D

Messenger, Woo, Sun, Martin: "A Ca2+-stimulated exosome release pathway in cancer cells is regulated by Munc13-4." dans: The Journal of cell biology, Vol. 217, Issue 8, pp. 2877-2890, (2018) (PubMed).

Woo, James, Martin: "Munc13-4 functions as a Ca(2+) sensor for homotypic secretory granule fusion to generate endosomal exocytic vacuoles." dans: Molecular biology of the cell, Vol. 28, Issue 6, pp. 792-808, (2017) (PubMed).

Man, Imig, Walter, Pinheiro, Stevens, Rettig, Sørensen, Cooper, Brose, Wojcik: "Identification of a Munc13-sensitive step in chromaffin cell large dense-core vesicle exocytosis." dans: eLife, Vol. 4, (2016) (PubMed).

Zur Stadt, Beutel, Kolberg, Schneppenheim, Kabisch, Janka, Hennies: "Mutation spectrum in children with primary hemophagocytic lymphohistiocytosis: molecular and functional analyses of PRF1, UNC13D, STX11, and RAB27A." dans: Human mutation, Vol. 27, Issue 1, pp. 62-8, (2005) (PubMed).

Feldmann, Callebaut, Raposo, Certain, Bacq, Dumont, Lambert, Ouachée-Chardin, Chedeville, Tamary, Minard-Colin, Vilmer, Blanche, Le Deist, Fischer, de Saint Basile: "Munc13-4 is essential for cytolytic granules fusion and is mutated in a form of familial hemophagocytic lymphohistiocytosis (FHL3)." dans: Cell, Vol. 115, Issue 4, pp. 461-73, (2003) (PubMed).

Synonymes et noms alternatifs relatifs à UNC13D

unc-13 homolog D (UNC13D), unc-13 homolog D (C. elegans) (Unc13d), unc-13 homolog D (Unc13d), transforming growth factor beta induced (TGFBI), unc-13 homolog D (unc13d), unc-13 homolog D (un13d), 2610108D09Rik, BIGH3, CDB1, CDG2, CDGG1, CSD, CSD1, CSD2, CSD3, EBMD, FHL3, HLH3, HPLH3, Jinx, LCD1, mFLJ00067, Munc13-4, UNC13D, Unc13h4

Protein level used designations for UNC13D

  • protein unc-13 homolog D
  • unc-13 homolog D (C. elegans)
  • likely ortholog of H. sapiens unc-13 homolog D (UNC13D)
  • RGD-CAP
  • RGD-containing collagen-associated protein
  • beta ig-h3
  • kerato-epithelin
  • transforming growth factor-beta-induced protein ig-h3
  • protein unc-13 homolog D-like
  • unc-13 homolog D
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