UNC13D Produits
(Unc-13 Homolog D (UNC13D))
Catégories
This gene encodes an RGD-containing protein that binds to type I, II and IV collagens. The RGD motif is found in many extracellular matrix proteins modulating cell adhesion and serves as a ligand recognition sequence for several integrins. This protein plays a role in cell-collagen interactions and may be involved in endochondrial bone formation in cartilage. The protein is induced by transforming growth factor-beta and acts to inhibit cell adhesion. Mutations in this gene are associated with multiple types of corneal dystrophy. [provided by RefSeq, Jul 2008].
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Catégories UNC13D en vedette
UNC13D Anticorps
High quality antibodies with extensive validation data.
UNC13D Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
UNC13D recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, ELISA
Validations
- (4)
N° du produit
ABIN531286
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IF, IHC (p), ICC
Validations
- (3)
N° du produit
ABIN2856569
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human, Mouse
Application
WB, ELISA, IHC
Validations
- (3)
N° du produit
ABIN185677
Quantité
100 μg
Fiche technique
Fiche technique
UNC13D recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN6219996
Quantité
96 tests
Fiche technique
Fiche technique
UNC13D recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1324647
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
N° du produit
ABIN3096260
Quantité
1 mg
Fiche technique
Fiche technique
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
N° du produit
ABIN2735014
Quantité
20 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits UNC13D
: "A Ca2+-stimulated exosome release pathway in cancer cells is regulated by Munc13-4." dans: The Journal of cell biology, Vol. 217, Issue 8, pp. 2877-2890, (2018) (PubMed).: "Munc13-4 functions as a Ca(2+) sensor for homotypic secretory granule fusion to generate endosomal exocytic vacuoles." dans: Molecular biology of the cell, Vol. 28, Issue 6, pp. 792-808, (2017) (PubMed).
: "Identification of a Munc13-sensitive step in chromaffin cell large dense-core vesicle exocytosis." dans: eLife, Vol. 4, (2016) (PubMed).
: "Mutation spectrum in children with primary hemophagocytic lymphohistiocytosis: molecular and functional analyses of PRF1, UNC13D, STX11, and RAB27A." dans: Human mutation, Vol. 27, Issue 1, pp. 62-8, (2005) (PubMed).
: "Munc13-4 is essential for cytolytic granules fusion and is mutated in a form of familial hemophagocytic lymphohistiocytosis (FHL3)." dans: Cell, Vol. 115, Issue 4, pp. 461-73, (2003) (PubMed).
Synonymes et noms alternatifs relatifs à UNC13D
unc-13 homolog D (UNC13D), unc-13 homolog D (C. elegans) (Unc13d), unc-13 homolog D (Unc13d), transforming growth factor beta induced (TGFBI), unc-13 homolog D (unc13d), unc-13 homolog D (un13d), 2610108D09Rik, BIGH3, CDB1, CDG2, CDGG1, CSD, CSD1, CSD2, CSD3, EBMD, FHL3, HLH3, HPLH3, Jinx, LCD1, mFLJ00067, Munc13-4, UNC13D, Unc13h4Protein level used designations for UNC13D
- protein unc-13 homolog D
- unc-13 homolog D (C. elegans)
- likely ortholog of H. sapiens unc-13 homolog D (UNC13D)
- RGD-CAP
- RGD-containing collagen-associated protein
- beta ig-h3
- kerato-epithelin
- transforming growth factor-beta-induced protein ig-h3
- protein unc-13 homolog D-like
- unc-13 homolog D
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