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UNG Produits

(Uracil-DNA Glycosylase (UNG))

Catégories

This gene encodes one of several uracil-DNA glycosylases. One important function of uracil-DNA glycosylases is to prevent mutagenesis by eliminating uracil from DNA molecules by cleaving the N-glycosylic bond and initiating the base-excision repair (BER) pathway. Uracil bases occur from cytosine deamination or misincorporation of dUMP residues. Alternative promoter usage and splicing of this gene leads to two different isoforms: the mitochondrial UNG1 and the nuclear UNG2. The UNG2 term was used as a previous symbol for the CCNO gene (GeneID 10309), which has been confused with this gene, in the literature and some databases. [provided by RefSeq, Nov 2010].

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Catégories UNG en vedette

UNG Anticorps

High quality antibodies with extensive validation data.

UNG Kits ELISA

Reliable ELISA kits for a wide range of species.

UNG Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

UNG recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (8)
N° du produit ABIN7436378
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human, Monkey
Application WB, IHC, IHC (p)
Validations
  • (5)
N° du produit ABIN1501681
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IF
Validations
  • (1)
  • (3)
N° du produit ABIN521262
Quantité 50 μg
Fiche technique Fiche technique

UNG recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6960380
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Competition ELISA
Validations
N° du produit ABIN5661967
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN5659762
Quantité 96 tests
Fiche technique Fiche technique

UNG recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1324669
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1324667
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7399127
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits UNG

Bj Rås, Sousa, Sharma, Fonseca, S Gaard, Bj Rås, Otterlei: "Monitoring of the spatial and temporal dynamics of BER/SSBR pathway proteins, including MYH, UNG2, MPG, NTH1 and NEIL1-3, during DNA replication." dans: Nucleic acids research, Vol. 45, Issue 14, pp. 8291-8301, (2017) (PubMed).

Esadze, Rodriguez, Weiser, Cole, Stivers: "Measurement of nanoscale DNA translocation by uracil DNA glycosylase in human cells." dans: Nucleic acids research, Vol. 45, Issue 21, pp. 12413-12424, (2017) (PubMed).

Hrecka, Hao, Shun, Kaur, Swanson, Florens, Washburn, Skowronski: "HIV-1 and HIV-2 exhibit divergent interactions with HLTF and UNG2 DNA repair proteins." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 113, Issue 27, pp. E3921-30, (2016) (PubMed).

Ryer, Ronning, Erdman, Schworer, Elmore, Peeler, Nevius, Lillvis, Garvin, Franklin, Kuivaniemi, Tromp: "The potential role of DNA methylation in abdominal aortic aneurysms." dans: International journal of molecular sciences, Vol. 16, Issue 5, pp. 11259-75, (2015) (PubMed).

Nakamura, Takahashi, Yamamoto-Fukuda, Horai, Nakashima, Arima, Nakamura, Koji, Kawakami: "Direct infection of primary salivary gland epithelial cells by human T lymphotropic virus type I in patients with Sjögren's syndrome." dans: Arthritis & rheumatology (Hoboken, N.J.), Vol. 67, Issue 4, pp. 1096-106, (2015) (PubMed).

Zhong, Chen, Zhang, Ren, Wu, Zhao, Liu, Zhao: "Epithelial-mesenchymal transition in keratocystic odontogenic tumor: possible role in locally aggressive behavior." dans: BioMed research international, Vol. 2015, pp. 168089, (2015) (PubMed).

Zhang, Chen, Wadham, McCaughan, Keane, Gorrell: "Dipeptidyl peptidase 9 subcellular localization and a role in cell adhesion involving focal adhesion kinase and paxillin." dans: Biochimica et biophysica acta, Vol. 1853, Issue 2, pp. 470-80, (2015) (PubMed).

Huan, Jiang, Liu, Shen: "Establishment of a dipeptidyl peptidases (DPP) 8/9 expressing cell model for evaluating the selectivity of DPP4 inhibitors." dans: Journal of pharmacological and toxicological methods, Vol. 71, pp. 8-12, (2015) (PubMed).

Sim, Nam, Lee, Lee, O, Joo, Liu, Han, Ki, Jeong, Lee, Lee: "Selective induction of hepatic cytochrome P450 2B activity by leelamine in vivo, as a potent novel inducer." dans: Archives of pharmacal research, Vol. 38, Issue 5, pp. 725-33, (2015) (PubMed).

Lühnsdorf, Epe, Khobta: "Excision of uracil from transcribed DNA negatively affects gene expression." dans: The Journal of biological chemistry, Vol. 289, Issue 32, pp. 22008-18, (2014) (PubMed).

Synonymes et noms alternatifs relatifs à UNG

uracil-DNA glycosylase (ung), uracil-DNA glycosylase (ung2), uracil-DNA glycosylase (Ung), uracil DNA glycosylase (UNG), uracil DNA glycosylase a (unga), uracil-DNA glycosylase Ung (ung), uracil-DNA glycosylase (STY2840), uracil-DNA-glycosylase (ung), uracil DNA glycosylase (Ung), uracil DNA glycosylase L homeolog (ung.L), uracil-DNA glycosylase (ANI_1_3358024), uracil-DNA glycosylase (AOR_1_1318164), uracil glycosylase (uglA), uracil-DNA glycosylase (Arnit_2731), temporal expression: early (D4R), An02g14790, AO090001000732, BA5648, DDBDRAFT_0204444, DDBDRAFT_0214910, DDB_0204444, DDB_0214910, DGU, ECK2578, HIGM4, HIGM5, JW2564, PSPTO4236, UDG, ung, UNG1, UNG2, UNG15, zgc:56102

Protein level used designations for UNG

  • uracil-DNA glycosylase
  • uracil-DNA glycosylase 1, uracil-DNA glycosylase 2
  • UDG
  • uracil-DNA glycosylase nuclear isoform
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