USP14 Produits
(Ubiquitin Specific Peptidase 14 (USP14))
Catégories
This gene encodes a member of the ubiquitin-specific processing (UBP) family of proteases that is a deubiquitinating enzyme (DUB) with His and Cys domains. This protein is located in the cytoplasm and cleaves the ubiquitin moiety from ubiquitin-fused precursors and ubiquitinylated proteins. Mice with a mutation that results in reduced expression of the ortholog of this protein are retarded for growth, develop severe tremors by 2 to 3 weeks of age followed by hindlimb paralysis and death by 6 to 10 weeks of age. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008].
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Catégories USP14 en vedette
USP14 Anticorps
High quality antibodies with extensive validation data.
USP14 Kits ELISA
Reliable ELISA kits for a wide range of species.
USP14 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
USP14 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, ELISA, IF
Validations
- (1)
- (8)
N° du produit
ABIN563939
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC (p)
Validations
- (1)
- (4)
N° du produit
ABIN388902
Quantité
400 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA
Validations
- (5)
N° du produit
ABIN563938
Quantité
50 μL
Fiche technique
Fiche technique
USP14 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6960351
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN5659744
Quantité
96 tests
Fiche technique
Fiche technique
USP14 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1324754
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1324752
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN2132479
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits USP14
: "Ubiquitin-specific protease-14 reduces cellular aggregates and protects against mutant huntingtin-induced cell degeneration: involvement of the proteasome and ER stress-activated kinase IRE1?." dans: Human molecular genetics, Vol. 23, Issue 22, pp. 5928-39, (2014) (PubMed).: "New genetic associations detected in a host response study to hepatitis B vaccine." dans: Genes and immunity, Vol. 11, Issue 3, pp. 232-8, (2010) (PubMed).
: "Phosphorylation analysis of primary human T lymphocytes using sequential IMAC and titanium oxide enrichment." dans: Journal of proteome research, Vol. 7, Issue 12, pp. 5167-76, (2009) (PubMed).
: "The proteasome-associated deubiquitinating enzyme Usp14 is essential for the maintenance of synaptic ubiquitin levels and the development of neuromuscular junctions." dans: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 29, Issue 35, pp. 10909-19, (2009) (PubMed).
: "USP14 inhibits ER-associated degradation via interaction with IRE1alpha." dans: Biochemical and biophysical research communications, Vol. 379, Issue 4, pp. 995-1000, (2009) (PubMed).
: "Deubiquitination of CXCR4 by USP14 is critical for both CXCL12-induced CXCR4 degradation and chemotaxis but not ERK ativation." dans: The Journal of biological chemistry, Vol. 284, Issue 9, pp. 5742-52, (2009) (PubMed).
: "Relative structural and functional roles of multiple deubiquitylating proteins associated with mammalian 26S proteasome." dans: Molecular biology of the cell, Vol. 19, Issue 3, pp. 1072-82, (2008) (PubMed).
: "Yeast two-hybrid screens imply involvement of Fanconi anemia proteins in transcription regulation, cell signaling, oxidative metabolism, and cellular transport." dans: Experimental cell research, Vol. 289, Issue 2, pp. 211-21, (2003) (PubMed).
: "Human and mouse proteases: a comparative genomic approach." dans: Nature reviews. Genetics, Vol. 4, Issue 7, pp. 544-58, (2003) (PubMed).
Synonymes et noms alternatifs relatifs à USP14
ubiquitin specific peptidase 14 (USP14), peptidase C19 family protein (usp14), ubiquitin specific peptidase 14 (Usp14), ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) (usp14), ubiquitin specific protease 14 (Bm1_28765), ubiquitin specific peptidase 14 S homeolog (usp14.S), ubiquitin specific peptidase 14 (usp14), universal stress protein (RR_RS06480), Ubiquitin carboxyl-terminal hydrolase 14 (usp-14), 2610005K12Rik, 2610037B11Rik, AW107924, ax, C78769, DDBDRAFT_0202821, DDBDRAFT_0237695, DDB_0202821, DDB_0237695, MGC69343, MGC81945, TGT, tgt, USP14, wu:fk63d09, zgc:55949Protein level used designations for USP14
- deubiquitinating enzyme 14
- tRNA-guanine transglycosylase, 60-kD subunit
- ubiquitin carboxyl-terminal hydrolase 14
- ubiquitin specific protease 14 (tRNA-guanine transglycosylase)
- ubiquitin thioesterase 14
- ubiquitin thiolesterase 14
- ubiquitin-specific processing protease 14
- ubiquitin-specific-processing protease 14
- ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)
- ubiquitin domain-containing protein
- ataxia
- dUB-type TGT for deubiquitinating enzyme
- ubiquitin specific protease 14
- universal stress protein
- queuine tRNA-ribosyltransferase
- ubiquitin carboxyl-terminal hydrolase 14-like
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