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USP22 Produits

(Ubiquitin Specific Peptidase 22 (USP22))

Catégories

Histone deubiquitinating component of the transcription regulatory histone acetylation (HAT) complex SAGA. Catalyzes the deubiquitination of both histones H2A and H2B, thereby acting as a coactivator. Recruited to specific gene promoters by activators, where it is required for transcription (By similarity).

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Catégories USP22 en vedette

USP22 Anticorps

High quality antibodies with extensive validation data.

USP22 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

USP22 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC (p)
Validations
  • (2)
  • (2)
N° du produit ABIN388914
Quantité 400 μL
Fiche technique Fiche technique
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish (Danio rerio)
Application WB
Validations
  • (4)
N° du produit ABIN2787647
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application ELISA, IHC, IF
Validations
  • (2)
N° du produit ABIN7174288
Quantité 100 μg
Fiche technique Fiche technique

USP22 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN6223780
Quantité 96 tests
Fiche technique Fiche technique

USP22 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN7125591
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
N° du produit ABIN3075103
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
N° du produit ABIN3122439
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits USP22

McCann, Vasilevskaya, Poudel Neupane, Shafi, McNair, Dylgjeri, Mandigo, Schiewer, Schrecengost, Gallagher, Stanek, McMahon, Berman-Booty, Ostrander, Knudsen: "USP22 functions as an oncogenic driver in prostate cancer by regulating cell proliferation and DNA repair." dans: Cancer research, (2019) (PubMed).

Kim, Hong, Park, Shin, Yoo, Jeon, Chung: "Deubiquitinating enzyme USP22 positively regulates c-Myc stability and tumorigenic activity in mammalian and breast cancer cells." dans: Journal of cellular physiology, Vol. 232, Issue 12, pp. 3664-3676, (2017) (PubMed).

Xiong, Li, He, Zeng, Zhang, He: "lncRNA HULC promotes the growth of hepatocellular carcinoma cells via stabilizing COX-2 protein." dans: Biochemical and biophysical research communications, Vol. 490, Issue 3, pp. 693-699, (2017) (PubMed).

Hong, Lee, Chung: "Ubiquitin-specific protease 22 (USP22) positively regulates RCAN1 protein levels through RCAN1 de-ubiquitination." dans: Journal of cellular physiology, Vol. 230, Issue 7, pp. 1651-60, (2015) (PubMed).

Wang, Zhu, Guo, Wang, Yang: "Decreased H2B monoubiquitination and overexpression of ubiquitin-specific protease enzyme 22 in malignant colon carcinoma." dans: Human pathology, Vol. 46, Issue 7, pp. 1006-14, (2015) (PubMed).

Vijayalingam, Subramanian, Zhao, Chinnadurai: "The Cellular Protein Complex Associated with a Transforming Region of E1A Contains c-MYC." dans: Journal of virology, Vol. 90, Issue 2, pp. 1070-9, (2015) (PubMed).

Xiao, Tian, Yang, Hu, Xie, Mei, Ding: "USP22 acts as an oncogene by regulating the stability of cyclooxygenase-2 in non-small cell lung cancer." dans: Biochemical and biophysical research communications, Vol. 460, Issue 3, pp. 703-8, (2015) (PubMed).

Schrecengost, Dean, Goodwin, Schiewer, Urban, Stanek, Sussman, Hicks, Birbe, Draganova-Tacheva, Visakorpi, DeMarzo, McMahon, Knudsen: "USP22 regulates oncogenic signaling pathways to drive lethal cancer progression." dans: Cancer research, Vol. 74, Issue 1, pp. 272-86, (2014) (PubMed).

Zhao, Lang, Ito, Bonnet, Metzger, Sawatsubashi, Suzuki, Le Guezennec, Stunnenberg, Krasnov, Georgieva, Schüle, Takeyama, Kato, Tora, Devys: "A TFTC/STAGA module mediates histone H2A and H2B deubiquitination, coactivates nuclear receptors, and counteracts heterochromatin silencing." dans: Molecular cell, Vol. 29, Issue 1, pp. 92-101, (2008) (PubMed).

Zhang, Varthi, Sykes, Phillips, Warzecha, Zhu, Wyce, Thorne, Berger, McMahon: "The putative cancer stem cell marker USP22 is a subunit of the human SAGA complex required for activated transcription and cell-cycle progression." dans: Molecular cell, Vol. 29, Issue 1, pp. 102-11, (2008) (PubMed).

Synonymes et noms alternatifs relatifs à USP22

ubiquitin specific peptidase 22 (USP22), ubiquitin specific peptidase 22 (Usp22), ubiquitin specific peptidase 22 (usp22), ubiquitin specific peptidase 22 S homeolog (usp22.S), AI427806, USP3L, usp3l, usp22, usp22 b, usp22-a, usp22-B, zgc:136342

Protein level used designations for USP22

  • deubiquitinating enzyme 22
  • ubiquitin carboxyl-terminal hydrolase 22
  • ubiquitin specific protease 22
  • ubiquitin thioesterase 22
  • ubiquitin thiolesterase 22
  • ubiquitin-specific processing protease 22
  • ubiquitin-specific-processing protease 22
  • ubiquitin specific peptidase 22
  • ubiquitin carboxyl-terminal hydrolase 22-like
  • Deubiquitinating enzyme 22-B
  • Ubiquitin thioesterase 22-B
  • Ubiquitin-specific-processing protease 22-B
  • deubiquitinating enzyme 22 B
  • ubiquitin carboxyl-terminal hydrolase 22-B
  • ubiquitin specific peptidase 22 b
  • ubiquitin thioesterase 22 B
  • ubiquitin thiolesterase 22-B
  • ubiquitin-specific-processing protease 22 B
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