WHSC2 Produits
(Wolf-Hirschhorn Syndrome Candidate 2 (WHSC2))
Catégories
This gene is expressed ubiquitously with higher levels in fetal than in adult tissues. It encodes a protein sharing 93% sequence identity with the mouse protein. Wolf-Hirschhorn syndrome (WHS) is a malformation syndrome associated with a hemizygous deletion of the distal short arm of chromosome 4. This gene is mapped to the 165 kb WHS critical region, and may play a role in the phenotype of the WHS or Pitt-Rogers-Danks syndrome. The encoded protein is found to be capable of reacting with HLA-A2-restricted and tumor-specific cytotoxic T lymphocytes, suggesting a target for use in specific immunotherapy for a large number of cancer patients. This protein has also been shown to be a member of the NELF (negative elongation factor) protein complex that participates in the regulation of RNA polymerase II transcription elongation. [provided by RefSeq, Jul 2008].
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Catégories WHSC2 en vedette
WHSC2 Anticorps
High quality antibodies with extensive validation data.
WHSC2 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
WHSC2 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC, FACS, ICC
Validations
- (2)
- (8)
N° du produit
ABIN1724802
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC, FACS, ICC
Validations
- (2)
- (8)
N° du produit
ABIN1724801
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human, Rat
Application
WB, ELISA, IHC, FACS, IF/ICC
Validations
- (7)
N° du produit
ABIN1846367
Quantité
100 μL
Fiche technique
Fiche technique
WHSC2 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN7125741
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1325325
Quantité
25 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN2132575
Quantité
50 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits WHSC2
: "Characterizing the functional consequences of haploinsufficiency of NELF-A (WHSC2) and SLBP identifies novel cellular phenotypes in Wolf-Hirschhorn syndrome." dans: Human molecular genetics, Vol. 21, Issue 10, pp. 2181-93, (2012) (PubMed).: "Cellular dynamics of the negative transcription elongation factor NELF." dans: Experimental cell research, Vol. 315, Issue 10, pp. 1693-705, (2009) (PubMed).
Synonymes et noms alternatifs relatifs à WHSC2
Negative elongation factor A (Nelf-A), negative elongation factor complex member A (Nelfa), negative elongation factor complex member A (nelfa), negative elongation factor complex member A L homeolog (nelfa.L), negative elongation factor complex member A (NELFA), negative elongation factor complex member A, Whsc2 (Nelfa), BcDNA:SD07139, CG5874, Dmel\\CG5874, fi75f03, MGC85474, NELF, NELF-A, nelf-a, nelfa, p/okcl.15, Whsc2, whsc2, WHSC2, Whsc2h, wu:fi75f03Protein level used designations for WHSC2
- CG5874-PA
- CG5874-PB
- NELF-A
- Nelf-A-PA
- Nelf-A-PB
- negative elongation factor A
- Wolf-Hirschhorn syndrome candidate 2 protein
- Wolf-Hirschhorn syndrome candidate 2
- negative elongation factor A-like
- wolf-Hirschhorn syndrome candidate 2 protein
- Wolf-Hirschhorn syndrome candidate 2 homolog
- mWHSC2
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