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WNT1 Produits

(Wingless-Type MMTV Integration Site Family, Member 1 (WNT1))
The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It is very conserved in evolution, and the protein encoded by this gene is known to be 98% identical to the mouse Wnt1 protein at the amino acid level. The studies in mouse indicate that the Wnt1 protein functions in the induction of the mesencephalon and cerebellum. This gene was originally considered as a candidate gene for Joubert syndrome, an autosomal recessive disorder with cerebellar hypoplasia as a leading feature. However, further studies suggested that the gene mutations might not have a significant role in Joubert syndrome. This gene is clustered with another family member, WNT10B, in the chromosome 12q13 region. [provided by RefSeq, Jul 2008].

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Catégories WNT1 en vedette

WNT1 Anticorps

High quality antibodies with extensive validation data.

WNT1 Kits ELISA

Reliable ELISA kits for a wide range of species.

WNT1 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

WNT1 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC, IF
Validations
  • (7)
N° du produit ABIN1683291
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro)
Validations
  • (4)
  • (4)
N° du produit ABIN733748
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human, Mouse
Application WB, ELISA, IHC, FACS, ICC
Validations
  • (1)
  • (4)
N° du produit ABIN969458
Quantité 100 μL
Fiche technique Fiche technique

WNT1 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
N° du produit ABIN6960531
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6971182
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6974918
Quantité 96 tests
Fiche technique Fiche technique

WNT1 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN7125731
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN5509532
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7386137
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits WNT1

Chen, Zhao, Han, Zhao, Mao, Cui, Chu, Feng, Yin, Wang, Wang, Xu, Zhao: "Wnt1 inhibits vascular smooth muscle cell calcification by promoting ANKH expression." dans: Journal of molecular and cellular cardiology, Vol. 135, pp. 10-21, (2020) (PubMed).

Tang, Peng, Huang, Xie, Chen, Shen, Gao, You, Xie, Chen: "Neoisoliquiritigenin Inhibits Tumor Progression by Targeting GRP78-β- catenin Signaling in Breast Cancer." dans: Current cancer drug targets, Vol. 18, Issue 4, pp. 390-399, (2018) (PubMed).

Chen, Chen, Wallace, Chen, Yang, Sung, Chiang, Chen, Chua, Yip, Cheng: "Combined therapy with melatonin and exendin-4 effectively attenuated the deterioration of renal function in rat cardiorenal syndrome." dans: American journal of translational research, Vol. 9, Issue 2, pp. 214-229, (2017) (PubMed).

Lii, Chang, Chen, Chen, Liu, Yeh, Wang, Liu, Tsai, Li: "Docosahexaenoic acid inhibits 12-O-tetradecanoylphorbol-13- acetate-induced fascin-1-dependent breast cancer cell migration by suppressing the PKCδ- and Wnt-1/β-catenin-mediated pathways." dans: Oncotarget, Vol. 7, Issue 18, pp. 25162-79, (2016) (PubMed).

Shan, Lv, Zhao, Liu, Sun, Xi, Xiao, Li: "Wnt/β-catenin pathway is required for epithelial to mesenchymal transition in CXCL12 over expressed breast cancer cells." dans: International journal of clinical and experimental pathology, Vol. 8, Issue 10, pp. 12357-67, (2016) (PubMed).

Toffart, Moro-Sibilot, Couraud, Merle, Perol, Girard, Souquet, Mastroianni, Ferretti, Romand, Chatellain, Vesin, Brambilla, Brambilla, Timsit: "Evaluation of RECIST in chemotherapy-treated lung cancer: the Pharmacogenoscan Study." dans: BMC cancer, Vol. 14, pp. 989, (2015) (PubMed).

Gao, Yang, Gao, Xu, Niu, Li, Wen: "Salvianolic acid B improves bone marrow-derived mesenchymal stem cell differentiation into alveolar epithelial cells type I via Wnt signaling." dans: Molecular medicine reports, Vol. 12, Issue 2, pp. 1971-6, (2015) (PubMed).

Mi, Li, Zhang, Zhao, Peng, Yang, Zheng: "MicroRNA-139-5p regulates C2C12 cell myogenesis through blocking Wnt/β-catenin signaling pathway." dans: Biochemistry and cell biology = Biochimie et biologie cellulaire, Vol. 93, Issue 1, pp. 8-15, (2015) (PubMed).

Banon-Maneus, Rovira, Ramirez-Bajo, Moya-Rull, Hierro-Garcia, Takenaka, Diekmann, Eickelberg, Königshoff, Campistol: "Wnt pathway activation in long term remnant rat model." dans: BioMed research international, Vol. 2014, pp. 324713, (2015) (PubMed).

Gao, Liu, Chen, Lv, Wu, Mi, Wang: "Comparative study of Hsp27, GSK3?, Wnt1 and PRDX3 in Hirschsprung's disease." dans: International journal of experimental pathology, Vol. 95, Issue 3, pp. 229-37, (2014) (PubMed).

Synonymes et noms alternatifs relatifs à WNT1

Wnt family member 1 (WNT1), Wnt family member 1 L homeolog (wnt1.L), wingless-type MMTV integration site family, member 1 (Wnt1), Wnt family member 1 (Wnt1), wingless-type MMTV integration site family, member 1 (wnt1), BMND16, int-1, Int-1, int1, INT1, Int1, OI15, sb:eu647, sw, swaying, wnt-1, Wnt-1, WNT-1, WNT1, wnt1-a, Xint-1, Xwnt1, zgc:194464, zgc:194478

Protein level used designations for WNT1

  • XWnt-1
  • protein Wnt-1
  • proto-oncogene Int-1
  • proto-oncogene Wnt-1
  • proto-oncogene protein Wnt-1
  • proto-oncogene Int-1 homolog
  • wingless-type MMTV integration site family, member 1 (oncogene INT1)
  • Wingless-type MMTV integration site 1 homolog
  • Wingless-type MMTV integration site 1, homolog
  • wingless-related MMTV integration site 1
  • murine mammary tumor virus integration site
  • etID22400.23
  • wingless-type MMTV integration site family member 1
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