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WRNIP1 Produits

(Werner Helicase Interacting Protein 1 (WRNIP1))
Werner's syndrome is a rare autosomal recessive disorder characterized by accelerated aging that is caused by defects in the Werner syndrome ATP-dependent helicase gene (WRN). The protein encoded by this gene interacts with the exonuclease-containing N-terminal portion of the Werner protein. This protein has a ubiquitin-binding zinc-finger domain in the N-terminus, an ATPase domain, and two leucine zipper motifs in the C-terminus. It has sequence similarity to replication factor C family proteins and is conserved from E. coli to human. This protein likely accumulates at sites of DNA damage by interacting with polyubiquinated proteins and also binds to DNA polymerase delta and increases the initiation frequency of DNA polymerase delta-mediated DNA synthesis. This protein also interacts with nucleoporins at nuclear pore complexes. Two transcript variants encoding different isoforms have been isolated for this gene. [provided by RefSeq, Jul 2012].

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Catégories WRNIP1 en vedette

WRNIP1 Anticorps

High quality antibodies with extensive validation data.

WRNIP1 Kits ELISA

Reliable ELISA kits for a wide range of species.

WRNIP1 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

WRNIP1 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Bat, Cow, Hamster, Human, Monkey, Mouse, Rat
Application WB, IHC, IHC (p)
Validations
  • (3)
N° du produit ABIN6736353
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA
Validations
  • (2)
N° du produit ABIN129611
Quantité 100 μg
Fiche technique Fiche technique

Application WB
Validations
  • (1)
  • (2)
N° du produit ABIN2775244
Quantité 100 μL
Fiche technique Fiche technique

WRNIP1 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method
Validations
N° du produit ABIN1123032
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method
Validations
N° du produit ABIN1123033
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rat
Analytical Method
Validations
N° du produit ABIN1123034
Quantité 96 tests
Fiche technique Fiche technique

WRNIP1 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
N° du produit ABIN3075618
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
N° du produit ABIN2715072
Quantité 20 μg
Fiche technique Fiche technique
Reactivity Rat
Source Yeast
Validations
N° du produit ABIN1624852
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits WRNIP1

Tsurimoto, Shinozaki, Yano, Seki, Enomoto: "Human Werner helicase interacting protein 1 (WRNIP1) functions as a novel modulator for DNA polymerase delta." dans: Genes to cells : devoted to molecular & cellular mechanisms, Vol. 10, Issue 1, pp. 13-22, (2005) (PubMed).

Kawabe Yi, Branzei, Hayashi, Suzuki, Masuko, Onoda, Heo, Ikeda, Shimamoto, Furuichi, Seki, Enomoto: "A novel protein interacts with the Werner's syndrome gene product physically and functionally." dans: The Journal of biological chemistry, Vol. 276, Issue 23, pp. 20364-9, (2001) (PubMed).

Synonymes et noms alternatifs relatifs à WRNIP1

Werner helicase interacting protein 1 (WRNIP1), Werner helicase interacting protein 1 L homeolog (wrnip1.L), Werner helicase interacting protein 1 (wrnip1), ATPase WRNIP1 (EDI_075920), ATPase WRNIP1 (CpipJ_CPIJ017857), ATPase WRNIP1 (PITG_07216), ATPase WRNIP1 (VDBG_02914), Werner helicase interacting protein 1 (Wrnip1), ATPase WRNIP1 (PGTG_08805), 4833444L21Rik, bA420G6.2, RP11-420G6.2, WHIP, Whip, Wrnip, WRNIP1, wrnip1, zgc:85976

Protein level used designations for WRNIP1

  • ATPase WRNIP1
  • Werner helicase interacting protein 1
  • Werner helicase-interacting protein 1
  • putative helicase RUVBL
  • Werner helicasae interacting protein 1
  • Werner syndrome homolog interacting protein
  • werner helicase-interacting protein 1
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